• search BSTP
  • cwru.edu
close button

For graduate school admissions

Visit the Office of Graduate Education for info on our many doctoral programs and the graduate education application process at the School of Medicine.

For medical school admissions

Visit the Office of Admission for info on application process, financial aid, and student life.

close button

Give online to the Biomedical Sciences PhD Fund

Use our secure online giving form to make your gift to Case Western Reserve University now.

Make a difference

Find out how you can Take Three Steps to make a difference at Case Western Reserve University.

close button

Welcome to campus

Visit Case Western Reserve University's uniquely urban campus, located in the heart of Cleveland's cultural hub, University Circle. Plan your trip:

W. David Sedwick, Ph.D.

Department of Medicine

Wolstein Research Building 3-131
(216) 844-7526



Mutational specificity at DNA sequence level, DNA damage and drug access, DNA repair, genetic susceptibility to cancer, colon cancer, mutagens and their specificity.


Radivoyevitch T, Loparo KA, Jackson RC, Sedwick WD. On systems and control approaches to therapeutic gain. BMC Cancer. 2006 Apr 25;6:104.

Meyers M, Hwang A, Wagner MW, Bruening AJ, Veigl ML, Sedwick WD, Boothman DA. A role for DNA mismatch repair in sensing and responding to fluoropyrimidine damage. Oncogene. 2003 Oct 20;22(47):7376-88. Review.

Yan T, Schupp JE, Hwang HS, Wagner MW, Berry SE, Strickfaden S, Veigl ML, Sedwick WD, Boothman DA, Kinsella TJ. Loss of DNA mismatch repair imparts defective cdc2 signaling and G(2) arrest responses without altering survival after ionizing radiation. Cancer Res. 2001 Nov 15;61(22):8290-7.

Sedwick WD, Markowitz SD, Veigl ML. Mismatch repair and drug responses in cancer. Drug Resist Updat. 1999 Oct;2(5):295-306.

Additional Publications