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Welcome to campus

Visit Case Western Reserve University's uniquely urban campus, located in the heart of Cleveland's cultural hub, University Circle. Plan your trip:

Scott Sieg, Ph.D.

Assistant Professor
Department of Medicine

AIDS Clinical Trials Unit
(216) 368-6594


Dr. Sieg graduated in Biology from LaRoche College in 1997. He completed his Ph.D. in Immunology from Case Western Reserve University in 1996. He is presently an Assistant Professor in the Department of Medicine of CWRU and Director of the Immune Function Core Lab of the Center for AIDS Research.



Jiang W, Lederman MM, Harding CV, Sieg SF. Presentation of soluble antigens to CD8+ T cells by CpG oligodeoxynucleotide-primed human naive B cells. J Immunol. 2011 Feb 15;186(4):2080-6.

Yonkers NL, Sieg S, Rodriguez B, Anthony DD. Reduced naive CD4 T cell numbers and impaired induction of CD27 in response to T cell receptor stimulation reflect a state of immune activation in chronic hepatitis C virus infection. J Infect Dis. 2011 Mar 1;203(5):635-45.

Pilch-Cooper HA, Sieg SF, Hope TJ, Koons A, Escola JM, Offord R, Veazey RS, Mosier DE, Clagett B, Medvik K, Jadlowsky JK, Chance MR, Kiselar JG, Hoxie JA, Collman RG, Riddick NE, Mercanti V, Hartley O, Lederman MM. Circulating human CD4 and CD8 T cells do not have large intracellular pools of CCR5. Blood. 2010 Nov 10. [Epub ahead of print]

Lederman MM, Alter G, Daskalakis DC, Rodriguez B, Sieg SF, Hardy G, Cho M, Anthony D, Harding C, Weinberg A, Silverman RH, Douek DC, Margolis L, Goldstein DB, Carrington M, Goedert JJ. Determinants of protection among HIV‐exposed seronegative persons: an overview. J Infect Dis. 2010 Nov 1;202 Suppl 3:S333-8. Review.

Additional Publications