To our daughters, Hannah and Abigail, and our parents, Nancy, Chan, and Ruth.

Acknowledgements

The authors wish to thank their colleagues, and present and former fellows, residents and medical students at the University Hospitals of Cleveland and Case Western Reserve University School of Medicine, many of whom helped bring cases to our attention. We also wish to give a special thanks to Dr. Dennis Landis and Dr. Robert Daroff for their inspiration. At Elsevier, Susan Pioli was instrumental in bringing this project to publication.