<% strPathPics = Session("strPathPicsL") imgBg = strPathPics + Session("strMedia") %> Midbrain Infarct

Midbrain Infarction

A 78 year-old woman developed the abrupt onset of a right third nerve palsy and a left hemiparesis. Sensation was intact.

Show the Infarction

Midbrain Infarction: ((Left) Flair axial MRI; (Right) Diffusion-weighted MRI. Note the bright signal on the diffusion-weighted image in the ventral midbrain and cerebral peduncle. Infarction in the midbrain results in a classic "crossed" neurology syndrome of an ipsilateral 3rd nerve palsy and a contralateral hemiparesis, known as Weber's syndrome.

This infarct is in the distribution of one perforating branch of the basilar artery. This lesion is usually caused by the occlusion of one paramedian basilar branch, due to lipohyalinosis, which occurs as a result of aging, diabetes and hypertension. Occasionally these lesions are associated with intrinsic disease of the basilar artery or an embolus to the basilar artery.


Revised 11/23/06
Copyrighted 2006. David C Preston