Arteriovenous Malformation - Case 4

A 35-year old woman presented with focal seizures affecting the left side of her body.


Show the Flow Voids of the AVM

Arteriovenous Malformation (AVM): T2-weighted axial MRIs. Note the abnormal collection of blood vessels in the right frontal lobe. Also note the large "flow voids" along the surface of the cortex which are the large draining veins of the AVM.

Arteriovenous malformations (AVMs) are a congenital abnormality of blood vessels. They consist of a tangle of abnormal vessels supplied by arterial feeders and often drained by large dilated veins. AVMs most often occur in isolation. Rarely, they are associated with genetic disorders, among them: Osler-Weber-Rendu syndrome (hereditary hemorrhagic telangiectasia), Sturge-Weber disease, and von Hippel-Lindau syndrome. AVMs are often asymptomatic. Symptoms, when present, may include:

• headaches (in some cases a unilateral throbbing headache, mimicking a migraine headache)

• seizures (focal, or focal to generalized)

• focal neurological deficits

• bleeding (may mimic subarachnoid hemorrhage from an aneurysm; bleeding from AVMs account for 2% of all strokes)

Larger AVMs are often seen on CT or MRI. Angiography is required to define the vascular anatomy and plan appropriate treatment. Treatment may involve surgical resection, embolization or radiotherapy.


Revised 11/29/06
Copyrighted 2006. David C Preston