Intramedullary Tumor - Ependymoma

A 35 year-old woman presented with progressive quadriparesis, numbness of all four extremities and urinary incontinence over six weeks.


Show the Tumor           Show the Syrinx           Show the Cord Edema           Show the GAD Enhancement

Ependymoma: Sagittal MRI scans of the cervical and thoracic spine; (Left) T2-weighted image; (Middle) T1-weighted image; (Right) T1-weighted with gadolinium (GAD) image. Note on the T2-weighted sagittal scan (left image), there is a large mass extending from C6-T2 that enhances with gadolinium (right image). In addition, there is a multi-loculated syrinx above and below the mass which is very bright on the T2-weighted image (consistent with water). Lastly, note the abnormal signal within the cord above the syrinx (at C1-C3), and below the syrinx (at T7); this is edema within the cord.

Neurosurgical exploration revealed a malignant intramedullary ependymoma. Ependymomas originate from ependymal cells located within the lining of the ventricles and in the central canal of the spinal cord. They are rare brain and spinal cord tumors, and more commonly affect children. This case also demonstrates that a syrinx typically occurs in one of the following situations: 1) as a congenital malformation; 2) in the setting of trauma; or 3) associated with a spinal neoplasm.


Revised 11/25/06
Copyrighted 2006. David C Preston