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Top of the Carotid Occlusion Treated with tPA

A 72 year-old woman presented with the acute onset of a left hemiplegia affecting the face, arm and leg, associated with a neglect syndrome and right eye deviation. After the initial CT showed no evidence of hemorrhage, IV tPA was administered followed by intra-arterial tPA. Two hours later, she was in a coma with bilateral Babinksi signs.

Note the Clot at the Top of the Carotid      Show the ECA Branches      Note the Flow in the ACA Post-tPA

Note the Flow in the MCA Post-tPA      Note the PComm Aneurysm

Top of the Carotid Occlusion: Cerebral angiogram, lateral view, right internal carotid artery (ICA) injection; (Left) Pre-tPA; (Right) Post-tPA. On the Pre-tPA film, note the occlusion at the top of the carotid artery with no filling of the anterior cerebral artery (ACA), and minimal filling of the middle cerebral artery (MCA). Indeed, the vessels above the internal carotid artery are actually branches off the external carotid artery (ECA) supplying the scalp. On the Post-tPA film, the ACA is well seen as are some of the M2 and M3 branches off the MCA. However, also note that there is a small posterior communicating (PComm) artery aneurysm present.

Revised 11/22/06
Copyrighted 2006. David C Preston