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Middle Cerebral Artery Occlusion Treated with tPA

A 63 year-old woman with atrial fibrillation presented with the acute onset of a left hemiplegia and neglect syndrome. After the CT showed no evidence of hemorrhage, IV tPA was administered followed by intra-arterial tPA. The next day, she still had a dense left hemiplegia with her eyes deviated to the right.

Show the MCA Occlusion

Middle Cerebral Artery Carotid Occlusion: Cerebral angiogram, AP view, right internal carotid injection; (Left) Pre-tPA; (Right) Post-tPA. On the pre-tPA film, note the occlusion at the right middle cerebral artery (MCA). On the post-tPA film, note that the clot has been dissolved and the MCA fills well. Despite recanalization, the patient did not improve clinically. ACA = anterior cerebral artery, ICA = internal carotid artery, MCA = middle cerebral artery.

Revised 11/29/06
Copyrighted 2006. David C Preston