Clinical Trials

NCRM researchers are conducting ground-breaking regenerative medicine and stem cell therapy clinical trials. Center experts help investigators develop clinical trials to investigate the efficacy and safety of cellular therapies.

Open Cellular Therapy Clinical Trials

CASE1Z16: Antigen Specific Adoptive T Cell Therapy for Opportunistic Cytomegalovirus Infection Occurring after Stem Cell Transplant
Investigator: Paolo Caimi, MD

CASE 2Z16: Phase I Trial of Universal Donor NK Cell Therapy in Combination With ALT803
Investigators: Foleshade Otegbeye, MD and David Wald, MD PhD

CASE 2417: AntiCD19 Chimeric Antigen Receptor T Cells for Relapsed or Refractory Non Hodgkin Lymphoma
Investigators: Paolo Caimi, MD and Marcos de Lima, MD

Cell-Based Therapy in Rheumatoid Arthritis: Proof of Concept Phase 1 Trial
Investigator: Nora Singer, MD

Impact of Mesenchymal Stem Cells in Knee Osteoarthritis
Investigator: James E. Voos, MD

Pending Cellular Therapy Clinical Trials

CASE 1A16: Dendritic Cell DKK1 Vaccine for Monoclonal Gammopathy and Stable or Smoldering Myeloma
Investigator: Ehsan Malek, MD

Percutaneous Image-Guided Delivery of Autologous Bone Marrow-Derived Mesenchymal Stem Cells for the Treatment of Symptomatic Degenerated Intervertebral Disc Disease
Investigator: Salim M Hayek, MD, PhD

Phase I Clinical Trial of Human AntiCD19 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Lymphoid Malignancies (Non-Hodgkin Lymphoma, Acute Lymphoblastic Leukemia, Chronic Lymphocytic Leukemia)
Investigator: Paolo Caimi, MD

A Phase II Study of Combination Treatment with Extracorporeal Photopheresis and Mesenchymal Stem Cell Infusion for High-Risk and Steroid-Refractory Acute GVHD
Investigator: Molly Gallogly, MD, PhD