CDC Grant Boosts Fight Against Tuberculosis

CDC Grant Boosts Fight Against Tuberculosis

Colored X-ray of a human chest with pulmonary tuberculosis in the patient’s left lung (fluffy red areas).

Researchers at Case Western Reserve University School of Medicine have been awarded a 10-year, $19.7-million contract from the U.S. Centers for Disease Control and Prevention (CDC) as an international clinical trial site for the Tuberculosis Trials Consortium (TBTC), a partnership of U.S. and international clinical investigators who conduct research about the diagnosis, treatment and prevention of tuberculosis (TB).

As the principal investigator, John L. Johnson, MD, professor of medicine at the School of Medicine and pulmonologist at University Hospitals Case Medical Center, will lead two research teams conducting clinical trials in Uganda and the Philippines. Researchers will test new drugs as well as shorter and simpler regimens for the treatment of TB, which sickens 9 million people around the world every year, according to the World Health Organization.

“The School of Medicine has a long tradition of excellence in basic, translational and clinical research in tuberculosis and has been at the forefront of international TB research for more than two decades,” says Johnson. “My lifetime research goal is to shorten the duration of anti-TB treatment required to treat most patients. This CDC contract funds TB researchers at Case Western Reserve to continue our work in conducting clinical trials to improve treatment.”