Brain Tumor Biobank

Researchers at Case Western Reserve University School of Medicine are leading a statewide effort to create an extensive biobank for the study of brain tumors.

Under the direction of principal investigator Jill Barnholtz-Sloan, PhD, an associate professor in the school's Department of General Medical Sciences and the Case Comprehensive Cancer Center, the Ohio Brain Tumor Study has been collecting tumor tissue, blood samples and other clinical and survival data from newly diagnosed brain tumor patients at four academic research centers across the state since 2007. The initiative is the only multi-center prospective brain tumor network in Ohio.

The variety of brain tumor types presents a particular challenge for researchers, Barnholtz-Sloan says. Now that the study has gathered a critical mass of tumor types to analyze, researchers are moving forward with a number of studies involving the genomics and proteomics of benign and malignant tumors.