NIMH Grant Renews Long-term Study of Childhood Psychiatric Disorders

A $7.8-million renewal grant from the National Institute of Mental Health will help researchers at Case Western Reserve University School of Medicine continue a long-term study of manic symptoms in children.

Elevated symptoms of mania, which include intense mood swings and irritability, are common indicators of bipolar disorder and other childhood psychiatric illnesses. Studying them over time could help researchers develop a more accurate way to diagnose bipolar disorder in children, says Robert L. Findling, MD, the Rocco L. Motto, MD, Professor of Child and Adolescent Psychiatry at the School of Medicine and director of child and adolescent psychiatry at University Hospitals Case Medical Center.

The funds will support continued evaluation of more than 700 children who participated in the initial study launched five years ago. The renewal will allow Findling and his team to add neurocognitive testing and neuroimaging to the study to search for biomarkers for bipolar disorder.