Mitchell L. Drumm, PhD

Professor, Departments of Pediatrics and Genetics

Mitchell L. Drumm, PhD is a Professor of Pediatrics and Genetics for the Case Western Reserve University School of Medicine. Dr. Drumm received his BS in genetics from The Ohio State University in 1983 and his PhD in Human Genetics from the University of Michigan in 1990. His doctoral degree was earned in the laboratory of Francis Collins, MD, PhD, with whom he was a co-discoverer of the gene that causes cystic fibrosis (CF).

Dr. Drumm's early work showed that CF cells could be corrected by introduction of a normal copy of the CF gene and laid the groundwork for studies in CF gene therapy. He also demonstrated that the most common mutation found in CF could be manipulated to exhibit activity and is credited with initiating the search for drugs that can correct the basic defect in CF. He has authored 60 peer-reviewed manuscripts and several book chapters on cystic fibrosis and holds three patents relevant to the disease as well.

In 2007, Dr. Drumm was appointed as Director of Basic Research of the Willard A. Bernbaum Cystic Fibrosis Research Center. His research program continues to focus on the genetics of CF, but he also invokes mouse genetics to better understand the disease. He directs an animal core facility that has the most comprehensive repertoire of CF mouse models in the world. Dr. Drumm also serves as an advisor to several cystic fibrosis research centers, reviews grants applications for the National Institutes of Health and co-chairs the Research and Research Training Committee of the Cystic Fibrosis Foundation.

In addition to his research program, Dr. Drumm also focuses on education. He directs a summer internship program through the Department of Pediatrics that provides laboratory experience to undergraduates from around the country, mentors undergraduate and graduate students in his lab as well as carry out didactic teaching in the Medical School. Dr. Drumm was awarded the Bruce M. Jackson award for undergraduate mentoring in 2009 for his work with CWRU undergraduates.