Bioinformatician / Senior Research Associate

Date: April 01, 2019

Title: Bioinformatician / Senior Research Associate

Department: Sekaly’s Lab - Pathology

School: Medicine

Location: Wolstein Research Building

Supervisor Name and Title: Rafick-Pierre Sekaly, the Richard J. Fasenmyer Professor of Immunopathogenesis.



The Bioinformatician works with internal and external collaborators to analyze and interpret high-throughput experiments including microarrays, mRNA-seq, microRNA-seq, DNA-seq and functional validation experiments.

The Bioinformaticians responsibilities will include statistical design of experiments, analysis and reporting, and assembly of figures for manuscript preparation.

You will be part of a highly motivated, multi-disciplinary team all driven by a passion to improve our understanding of the molecular mechanisms that drive complex, chronic diseases and response to treatment.



  1. Work with moderate independence, perform all phases of high-throughput data analysis from data processing and quality control through final analytical results
  2. Work with computational tools for the exploration of high-dimensionality datasets and test statistical models
  3. Work with researchers to translate these models and analyze data from experiments
  4. Perform analysis of biomedical research data using descriptive statistics and inference tests
  5. Supporting scientists by assessing their bioinformatics needs and defining proper informatics solution(s)
  6. Write, submit, and help with grant applications
  7. Produce high quality scientific reports, presentations and papers.
  8. Help develop toolsets and bioinformatics applications that embed analysis methodologies



Perform other duties such as coordinate and facilitate collaborative experiments with other investigators



Department: Daily contact with supervisor and Department Staff

University: Frequent contact with other departments

External: Occasional contact with vendors to exchange information

Students: Continuous contact with students to provide information and analytical assistance




Department: Sekaly’s Lab - Pathology

University: Case Western Reserve University



The position does not include any direct supervisory responsibility



Experience: 3 to 5 years of related experience post-graduation required

Education/Licensing: Ph.D. in Bioinformatics/Statistics/Math or related field



  1. Work experience in at least one scripting language such as R or Python.
  2. Work experience with Linux, shell scripting and HPC environment.
  3. Previous experience in the field of immunology is a plus.
  4. Ability to work effectively independently and collaboratively within a team. Must be highly motivated, responsible, dependable and a self-starter.  Must demonstrate a strong desire to learn and to advance research.
  5. Professional and effective oral and written communication skills; and good interpersonal skills with the ability to work and communicate with various individuals within and external to the University.  Must be able to clearly relay information to the PI and other researchers and prepare written documents for grant submissions, manuscripts, publications, etc. as needed.
  6. Strong organization skills; ability to multi-task, prioritize and meet deadlines. Must demonstrate attention to detail and accuracy, time management skills, and follow-through.
  7. Must demonstrate flexibility and ability to work under pressure; must be able and willing to conform to shifting priorities, demands and timeline.



Position will include occasional travel.



In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.



Qualified applicants should send their CV to