Postdoctoral Fellow Positions - Computational Biology, Macromolecular Structure Determination, and Drug Design (Pharmacology)

Postdoctoral Fellow Positions in Computational Biology, Macromolecular Structure Determination, and Drug Design

Postdoctoral fellow positions are available in the Taylor Lab in the Department of Pharmacology at Case Western Reserve University in Cleveland, OH.

We are looking for motivated and passionate individuals to integrate computational/molecular modeling, structure determination, and functional biochemical assays with cellular phenotype as a part of our research team. Our lab seeks to understand fundamental, biological processes and how these pathways are abrogated in disease states. We are particularly interested in understanding telomere maintenance, cell signaling through post-translational modification, and the role of prostaglandin signaling in stem cell differentiation and tissue regeneration. The detailed information garnered from the basic science is used to develop pharmacological agents.  Experience in computational, biophysical, biochemical, or structural application and/or advanced protein expression and purification strategies will be considered important advantages. The candidate will be part of a multidisciplinary team working to develop small molecule agonists and antagonists.

Applicant qualifications include a strong background in any of the following areas: 1) Electron microscopy, x-ray crystallography, or NMR spectroscopy of biological specimens;  

2) Computational Biology, including molecular dynamic simulations or modeling;

3) Quantitative Biophysics, Biochemistry, or Structural Biology;

4) Candidates from protein expression and purification or large-scale mammalian tissue culture backgrounds with an interest in biophysics and structure determination are also encouraged to apply.

Interested candidates should e-mail a cover letter, CV, publications list, and names and contact information for three references to Dr. Derek Taylor. (