Research Associate - Department of Biochemistry

Research Associate - Department of Biochemistry



January 20, 2022

Research Associate Position 


Case Western Reserve University, Cleveland, Ohio, USA



Human diseases are caused by the interplay between gene and environment.  Deep sequencing reveals millions of mutations between the genomes of unrelated individuals; however, the consequences of these mutations remain mostly unclear. Besides genetic impact, the actual development of individuals' disease phenotypes is largely subjected to their lifestyle, behavior, and environmental exposures. Characterizing these highly diverse and dynamic factors goes beyond what can be achieved with regular medical records.

To enable precision medicine and health, my lab seeks to address these gaps by investigating the areas which have not been extensively studied before. On the genetic side, we will focus on investigating the impact of genetic variation on post-transcriptional regulation to study the mechanistic role of RNA binding proteins in human diseases. On the non-genetic side, we will exploit the emerging wearable technology for deep phenotypical and environmental profiling. With the big data strategy integrating multi-omics, phenotypical, and environmental datasets, we are delineating the gene-environment interaction at a personal resolution to achieve precise understandings of human diseases.

The Department of Biochemistry and Center for RNA Science and Therapeutics has a highly interactive environment with state-of-the are facilities and outstanding core laboratories. Excellent stipends and benefits packages are available.

Interested candidates should send a Cover Letter, current CV, and names and contact information for 3 references to: Xiao Li, (