Title: Research Associate
Department: Dermatology School: Medicine Location: 5028
Supervisor Name and Title: Nicole L. Ward, Ph.D. Associate Professor and/or Thomas McCormick Ph.D., Associate Professor
Work independently to design and carry out research in a dermatology laboratory using molecular, genetic and cellular biology techniques. This position will advance translational discovery and application in psoriasis using a novel approach that tightly integrates and coordinates basic and preclinical research with cutting-edge systems biology, patient-centered data and data mining within a rich and synergistic interactive/collaborative and institutional environment.
The ideal candidate will have a strong background in molecular biology, animal models, informatics and an interest in immunology. Candidates should be able to perform and analyze experiments independently. Strong verbal, written and presentation skills are expected to enable efficient communications of experimental finding both orally and in writing. Salary in commensurate with experience. Position is available immediately for five years and is fully funded benefits. This position will work with animals.
1) Develop the experimental design for the project, carry out the experiments at the bench and perform day-to-day data analysis.
2) Conduct bench-top assays directed towards measuring different parameters of immune response in blood and tissues, both murine and human.
3) Participate in on-going clinical studies including processing tissue samples (blood, biopsy), perform the cellular analysis using flow cytometry, immunohistochemistry and molecular analyses (e.g., quantitative-RT-PCR,ELISA, NanoString) and participate in completing the statistical analyses.
4) Interact closely with the Preclinical Animal Core and the Applied Multi’Omics Core to plan experiments, generate and integrate data, and work effectively as part of a larger team to ensure a focused and efficient hand off of experimental information.
5) Work with and supervise laboratory staff (Research Assistants, Research Technicians and students).
6) Work collaboratively with other senior research staff as directed by the Pis (Nicole L. Ward, Thomas S. McCormick) or CORT corresponding PI (Kevin D. Cooper).
7) Maintain all required certifications and training required to participate in both human-based and animals-based biomedical research.
8) Prepare scientific manuscripts including writing the manuscript and generating the figures, and contribute preliminary data, background, significance and experimental design for grant proposals.
9) The ability to work independently for key sub-projects is necessary, while working in a team setup for larger collaborative projects is also desirable.
1) General laboratory maintenance.
2) Perform other duties as assigned.
Department: Daily contact with supervisors to discuss research and updates on the experiments. Contact with the Skin Study Center, Dermatopatholgy and the Preclinical Animal Core.
UniversityL Contact with the Animal Resource Center and the applied Multi’omics Core.
External: Contact with collaborating laboratories outside CWRU.
Students: May teach techniques to laboratory staff, undergraduates or other new personnel in the lab.
The position has direct supervision of staff employees. Train new staff; directs the work of students.
PhD in immunology, molecular and/or cellular biology preferred.
A background in dermatology, rheumatology or inflammatory/autoimmune disease is preferred, proficiency in bioinformatics is desirable.
0-3 years of experience in biomedical research post
Ph.D. Record of multiple peer-reviewed publications
Required Knowledge, Skills and Abilities:
The successful candidate will have a strong background in cellular or molecular biology, immunology or other closely related fields; experience in laboratory rodents and human clinical samples is desirable; experience in common cell and molecular biology techniques is necessary, experience in bioinformatics or systems biology would be a plus. The following qualities are also greatly valued; highly motivated, responsible, dependable and a self-starter; excellent oral and written communications skills and interpersonal skills; excellent organization skills; ability to multi-task, prioritize and meet deadlines; attention to detail and accuracy; ability to work effectively independently and collaboratively with others on and off campus.
General laboratory environment. May have exposure to hazards. Will be working with human and rodent-derived primary and cell lines. May be required to lift up to 40 pounds at a time infrequently. May have repetitive motion with hands and substantial time analyzing culture dishes with cells.
Case’s animal facilities are accredited by the Association for the Assessment and Accreditation of Laboratory Animal Care (AAALAC) and is managed according to the “Guide for the Care and Use of laboratory Animals” appropriate Federal Animal Welfare Regulations, and the Public Health Service “Policy on the Human Care and are subject to internal compliance to SOM Animal Resource center Standard Operating Procedures and to compliance regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines, the State of Ohio Veterinary Practice Act, Federal Drug Enforcement Administration regulatory guidelines, Us Food and Drug Administration Center for Veterinary Medicine regulations and other applicable regulatory guidelines.
***Two positions available. Please send cover letter and resume to firstname.lastname@example.org.
In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.
Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Inclusion, Diversity and Equal Opportunity at 216-368-8877 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.