Work independently to design and execute unbiased discovery research in neurodegeneration using proteomic, biochemical, molecular, genetic and cellular biology techniques. This position will advance the translational applications of basic science discovery in animal and cellular models of neuropsychiatric disease, with particular emphasis on neurodegeneration.
The ideal candidate will have a strong background in proteomics, biochemistry, neuroscience, molecular biology, genetic preclinical models of disease, and cell biology. Candidate must be able to perform and analyze experiments independently. Strong verbal, written and presentation skills are expected to enable efficient communication of experimental findings in both oral form and written publication. Salary is commensurate with experience. Position is available immediately and is fully funded with benefits. This position will require extensive work with mice and rats.
Develop the experimental design for the project, carry out the experiments at the bench and perform day-to-day data analysis.
Work with and supervise laboratory staff (Research Assistants, Research Technicians and students).
Work collaboratively with other senior research staff as directed by the PI, both within our institution and with laboratories and companies outside of our institution.
Maintain all required certifications and training required to participate in animal-based biomedical research.
Prepare scientific manuscripts including writing the manuscript and generating the figures, and contribute preliminary data, background, significance and experimental design for grant proposals.
The ability to work independently for key sub-projects is necessary, as well as the ability for working in a team setup for larger collaborative projects.
General Lab Maintenance
Perform other duties as assigned
Daily contact with supervisor to discuss experiments and general research.
University contact with Animal Resource Center.
Contact with collaborating laboratories outside of CWRU.
May teach techniques to laboratory staff, undergraduates or other new personnel in the lab.
Direct the work of students and support staff.
PhD in Biochemistry, Biotechnology, or Proteomics
Background in neurodegeneration research is preferred.
0-3 years of research in biomedical research post
Record of peer-reviewed publications.
The successful candidate will have technical expertise in (1) DNA, RNA and protein extraction; (2) SDS-PAGE and western blotting; (3) real time PCR; (4) 2D gel electrophoresis; (5) immunohistochemistry; (6) histopathology; (7) primary animal cell culture; (8) animal breeding, injection and oral gavage; (9) brain dissection; (10) general computer knowledge and figure preparation for presentation, publication and grant application.
This successful candidate must be highly motivated, responsible, dependable and a self-starter; excellent oral and written communications skills and interpersonal skills; excellent organization skills; ability to multi-task, prioritize and meet deadlines; attention to detail and accuracy; ability to work effectively independently and collaboratively with others on and off campus, and dedication to honesty, rigorous experimentation, and respect for others.
General laboratory environment. May have exposure to hazards. Will be working with rats and mice, as well as rodent and human-derived cells and sometimes human pathological tissue. May have repetitive motion with hands through experimental techniques
Interested candidates should send CV to Dr. Andrew Pieper, c/o Laura Dillon (firstname.lastname@example.org)
In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.
Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Inclusion, Diversity and Equal Opportunity at 216-368-8877 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.