Research Associate, Radiology

Department:

Radiology / Case Center for Imaging Research                      

Supervisor Name and Title:

Agata Exner, Professor          

I. STATEMENT OF RESEARCH AND SCIENTIFIC RESPONSIBILITIES

The Research Associate will be responsible for overseeing the day-to-day operations of the lab. The appointed candidate will be responsible for practical aspects of the lab, including but not limited to: operation and maintenance of laboratory instruments/equipment, management and safety of the internal and external users of the lab and equipment, maintenance of general supplies, inventory and ordering needed to ensure the lab runs smoothly. The candidate will also be partially responsible for tasks such as coordinating lab activities and meetings, designing, evaluating, and optimizing experimental techniques. Some limited supervisory duties of graduate and undergraduate students will also be expected

In addition, the RA will be responsible for planning and executing duties necessary to maintain active inter and intra-institutional collaborations, including preparation and shipping of materials and samples, filing appropriate paperwork such as material transfer agreements, communications and follow-up with collaborator laboratories and navigation of overall project management for between 3-5 projects with some limited supervision from the PI.

The RA / Laboratory Manager will be, in limited capacity, expected to conceptualize, design, and implement experiments for the generation of new knowledge, applications, or understanding at the forefront of the discipline, and to adjust the research design or methodology in the light of unforeseen problems.

He/she will, with limited oversight, perform experiments and data analysis utilizing tools available in the laboratory and will participate in the development of new tools if necessary. As a postdoc he/she will also work with others to prepare manuscripts and contribute preliminary data, background and significance and experimental design for grant proposals.

Ideal candidate will have strong organizational skills, and be able to pay close attention to detail and accuracy. He/she will also have effective communication skills. The candidate will be expected to exercise initiative, personal responsibility and accountability in both personal and group contexts; work effectively with others, make decisions independently in complex contexts, and have the ability to manage their own learning in changing circumstances.

Currently the laboratory conducts research in the development of multifunctional contrast agents for ultrasound imaging and therapy of cancer.  We are also developing new noninvasive biopsy approaches to tumor diagnosis as well as a number of other interventional radiology approaches. Research will primarily be focused on the formulation, characterization and assessment of various ultrasound-active systems for detection and treatment of cancer.

TECHNICAL SKILLS

The candidate will be familiar with chemical synthesis and analytical methodology, nanomedicine, aspects of nanoparticle formulation and characterization, as well as general wet laboratory techniques. The candidate will also need to become familiar with medical image acquisition and processing, handling, care and use of laboratory animals and surgical procedures related to tumor inoculation and therapy.

Other related skills: Development and optimization of new methodologies and validation of the existing approaches, specifically in formulation, characterization and assessment of ultrasound contrast agents, or nanobubbles, and microbubbles along with related cell and in vivo assays. Also helpful would be some knowledge of cell culture and cell-based assays.

II. SUPERVISORY RESPONSIBILIES

Supervise trainees such as graduate students and undergraduate students in conducting using various equipment in the laboratory, sample preparation, experimental design and data analysis of a variety of projects.

III. EDUCATION REQUIREMENTS

PhD in Biomedical Engineering [or Radiological Sciences or related field]

IV.   YEARS OF RELEVANT EXPERIENCE REQUIRED

0-1 years of postdoctoral experience

Multiple publications in peer reviewed journals

Specific Duties:

  • Be familiar with the regulatory requirements specific to the lab and ensures all users are incompliance with those standards

  • Communicate and enforces laboratory safety rules to internal and external researchers working in the lab, and make sure that lab members are wearing the appropriate PPE

  • Update and maintain the Lab Safety Manual and other required safety documents required by EHS

  • Be familiar with IACUC operations, protocols and general animal research

  • Oversee laboratory cleanliness and ensures that the laboratory is complaint with all regulations.

  • Ensure lab equipment is functioning properly and take appropriate action when issues/malfunctions are identified

  • Maintain research laboratory supplies inventory by anticipating needed supplies, placing and expediting orders for supplies, and verifying receipt of supplies.

  • Manage and update chemical inventories

  • Ensure lab staff have been trained on the correct use of the lab equipment

  • Mentor and when needed discipline lab members for not following policies/procedures that have been established for the lab.

  • Help schedule safety training for new lab users and retraining for lab users who are in need of refresher training to include: equipment training, safety training and/or lab safety plan reviews and ensure the training has been documented.

  • Ensure that the laboratory is kept clean and orderly

Please submit all cover letter and resume to agata.exner@case.edu

In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity.  Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.

Case Western Reserve University provides reasonable accommodations to applicants with disabilities.  Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Inclusion, Diversity and Equal Opportunity at 216-368-8877 to request a reasonable accommodation.  Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.