Title: Research Associate
School: School of Medicine
Location: BRB 3rd Floor
Supervisor Name and Title: Raymond Muzic PhD, Professor of Radiology
A research associate position is available to work in a multi-disciplinary and multi-investigator team consisting of physicians, engineers, and chemists within the Department of Radiation Oncology at Case Western Reserve University School of Medicine. The research associate will be working directly with the team characterizing glucose transport and metabolism in gynecological and genitourinary malignancies using animal and cell culture models. The candidate must have hands-on experience in the generation of genetically modified cell and murine models as well as interrogating tumor xenograft growth in immunocompromised mice. Strong fundamental knowledge in cancer biology is required as well as standard molecular techniques such as cell culture, sequencing, flow cytometry, qRT-PCR, Western blot, gamma H2AX, and clonogenic assays. Prior experience and expertise with DNA repair is highly desired. The candidate is expected to have excellent oral and written communication skills and be highly involved in writing manuscripts for peer reviewed journals, preparing for oral presentations at various meetings, and providing assistance with writing grant proposals. Qualified applicants must hold a doctoral degree in biomedical sciences with sub-specialties in any of Genetics, Cell Biology, Cancer Biology, Biochemistry, Molecular Biology, Pharmacology, Biotechnology or in other relevant fields. Students about to graduate and recent graduates with less than 2 years of prior postdoctoral experience are encouraged to apply.
Highly motivated individuals should submit via email a brief description of their research interests (1 page cover letter), full CV, and contact information:
Prof. Raymond F. Muzic, Jr.
Department of Radiology
Case Western Reserve University School of Medicine
1. Conduct research.
2. Design, plan, and execute experiments.
3. Present data, progress reports, and current literature to laboratory and national meetings.
4. Survey current literature to keep abreast of historical and trends in various research topics.
5. Write manuscripts and aid in grant proposal submissions.
1. Perform other duties as assigned.
2. Maintain safe, working laboratory environment.
Department: Collaborators and members of other laboratories (50% of time); PI (50%)
Students: Laboratory personnel, including students (100%)
Undergraduates and high school students doing summer research
Experience: Candidate must have a minimum experience of conducting biomedical research using techniques in molecular and cellular biology with publications in high impact journals.
Education/Licensing: Minimum of PhD in chemistry is required with minimum of 5 years of postdoctoral research experience.
REQUIRED KNOWLEDGE, SKILLS and ABILITIES
1. Knowledge and understanding of commonly-used concepts, practices, and procedures within the field of biomedical sciences.
2. Ability to perform standard techniques in biochemistry, and molecular and cellular biology.
3. Must demonstrate compliance with CWRU animal research and care (ARC) policies and procedures and compliance to regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines and other applicable regulatory guidelines.
4. Must demonstrate compassion for animals within CWRU facilities and dedication to the Animal Resource Center’s mission. Must handle animals with care and respect at all times.
5. Previous experience working with animals preferred.
6. Knowledge and understanding of/Working knowledge of/Demonstrated ability to cancer imaging and biology preferred.
7. Excellent oral and written communication skills and interpersonal skills; must demonstrate the ability to effectively and professionally communicate and work with various individuals from a broad spectrum of disciplines, technical and educational backgrounds within the department, School and University, and with individuals outside the University.
8. Good/Strong organization skills; ability to multitask, prioritize and meet deadlines. Must demonstrate attention to detail and accuracy, time management skills, and follow-through.
9. Effective management skills; ability to lead, train, work with, and elicit cooperation from team members and staff.
10. Ability to work effectively independently and collaboratively within a team. (Must be highly motivated, responsible, dependable and a self-starter.)
11. Ability to work with sensitive information and maintain confidentiality.
12. Effective problem-solving skills; must demonstrate excellent analytical skills, sound judgment and good decision-making.
13. Must demonstrate flexibility and ability to work under pressure; must be able and willing to work in a fast-paced, changing environment, and conform to shifting priorities, demands and timeline.
14. Willingness and ability to rely on and follow instructions and pre-established guidelines to perform the functions of the job.
15. Ability to operate laboratory equipment.
16. Proficiency in Microsoft Office (ex: Word, Excel, PowerPoint, Access, Publisher) and database management.
17. Must demonstrate a willingness to learn new techniques, procedures, processes, and computer programs as needed.
18. Must be able and willing to maintain a high standard of personal cleanliness and utilize protective gear to protect the health of the animals.
Position will be in a laboratory environment with potential exposures to hazardous materials, including but not limited to, chemicals and radiation. Successful candidates will adhere to protocols prescribed by CWRU Environmental Health Services to uphold strict safety standards. Case's animal facilities are accredited by the Association for the Assessment and Accreditation of Laboratory Animal Care (AAALAC) and is managed according to the "Guide for the Care and Use of Laboratory Animals” appropriate Federal Animal Welfare Regulations, and the Public Health Service “Policy on the Humane Care and Use of Laboratory Animals." This position, and all animal research personnel, are subject to internal compliance to SOM Animal Resource Center Standard Operating Procedures and to compliance regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines, the State of Ohio Veterinary Practice Act, Federal Drug Enforcement Administration regulatory guidelines, US Food and Drug Administration Center for Veterinary Medicine regulations and other applicable regulatory guidelines.
In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.