Research Scientist - Department of Psychiatry

Date: 6/21/2021

Title: Research Scientist

Department: Department of Psychiatry

School: School of Medicine

Location:  Wolstein Research Building 

Supervisor Name and Title: Andrew A. Pieper, MD, PhD.; Professor, Case Western Reserve University


The Department of Psychiatry at Case Western Reserve University School of Medicine is seeking to fill the full time position of Research Scientist. Candidates must have a strong background in biochemistry or molecular biology, with particular interest in neuropsychiatry and brain health. Special consideration will be given to candidates with previous expertise in traumatic brain injury and Alzheimer’s disease. Additional experience in the neurovascular unit applied to brain health is greatly appreciated. With minimum mentorship, the selected candidate will be expected to develop new research directions, generate novel hypotheses related to neuroprotection and brain health, design in vitro and in vivo experiments with existing and new models of neurodegeneration, interpret data, prepare manuscripts for publication, and present discoveries at departmental seminars and national and international scientific meetings. The research scientist is expected to participate in the research design phase and in the preparation of research proposals that will be initiated by the candidate or other investigators. The research scientist is expected to be an independent researcher in this area of interest, notwithstanding group or collaborative science. It is also expected that the Research Scientist will apply for grant funding as Principal Investigator. The selected candidate will also participate collaboratively with other Principal Investigators within and outside of CWRU. The position will require the Research Scientist to perform tasks in an organized manner, work accurately, meet deadlines, and employ excellent problem-solving skills. The Research Scientist will also be expected to provide supportive mentorship and teaching to junior members of the laboratory.



  1. Work with preclinical models of disease and injury, most keenly with rodent-based models for biomedical applications. 
  2. Plan and execute projects in collaboration with faculty members from CWRU and other institutions.
  3. Work with advanced biochemical and molecular biology techniques, including analysis and interpretation of large data sets. 
  4. Independently write and apply for research grants as principal investigator.
  5. Prepare manuscripts and contribute preliminary data, background and significance, and experimental design for grant proposals as a collaborator or co-PI. 



  1. Perform other duties as assigned. 



Department: Weekly to Bi-weekly meetings with Principal Investigator/Supervisor

University: Occasional contact with other departments

External: Limited or no contact with vendors to exchange information. 

Students: Contact with postdoctoral scholars, graduates and undergraduate student employees, as well as rotating graduate students and summer students in collaboration with other institutions.


SUPERVISORY RESPONSIBILITY: Supervise postdoctoral scholars, graduate students and undergraduate students in experimental design and data analysis for a variety of projects. 



Experience: High level of experience in a research-intensive environment, and a track record that includes high-tier (impact factor > 7) peer-reviewed publications. Extensive knowledge and experience with a multitude of advanced biochemistry techniques such as qPCR, CRISPR, virus design, immunohistochemistry staining, animal behavior, enzymatic activity assays. 

Education/Licensing: Candidates should have a Ph.D. in related discipline such as biochemistry or molecular biology. Prior post-doctoral research experience is strongly preferred. The candidate should maintain all required certifications and training to participate in animal-based biomedical research.



  1. Demonstrated expertise in biochemistry and molecular biology.
  2. Ability to effectively perform and train others in research techniques, animal procedures, Immunohistochemistry and biochemical analysis.  
  3. Ability to operate laboratory equipment.
  4. Excellent oral and written communication skills and interpersonal skills; must demonstrate the ability to effectively and professionally communicate and work with various individuals from a broad spectrum of disciplines, technical and educational backgrounds within the department, School and University, and with individuals outside the University.
  5. Strong organization skills; ability to multi-task, prioritize and meet deadlines.  Must demonstrate attention to detail and accuracy, time management skills, and follow-through.   
  6. Effective management skills; ability to lead, train, work with, and elicit cooperation from team members and staff.  
  7. Ability to work effectively independently and collaboratively within a team.  Must be highly motivated, responsible, dependable and a self-starter. 
  8. Ability to work with sensitive information and maintain confidentiality.  
  9. Effective problem-solving skills; must demonstrate excellent analytical skills, sound judgment and good decision-making.  
  10. Must demonstrate flexibility and ability to work under pressure; must be able and willing to work in a fast-paced, changing environment, and conform to shifting priorities, demands and timeline.  
  11. Willingness and ability to rely on and follow instructions and pre-established guidelines to perform the functions of the job.
  12. Good computer skills, including database management.  
  13. Must display the highest ethical standard and respect for others at all times, including attention to the merits of diversity.  Must display rigorous honesty at all times and be a role model for others in the lab.


WORKING CONDITIONS: General laboratory environment. May have exposure to chemical hazards. Will be working with animal in a research setting. 



In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity.  Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.


Please submit by e-mail a cover letter and curriculum vitae to Dr. Andrew A. Pieper at