Research Scientist - Genetic and Genome Sciences


The objective of this position is to conceive, design and implement high impact colon cancer research projects with translational goals. The research scientist is expected to independently apply for grant funding as PI and to work with the supervisor to mentor postdoctoral fellows and graduate student.



1.       Conceive, design and implement colon cancer research projects with high likelihood to be funded (10%).

2.       Grant Writing- Working Independently with Dr. Wang and/or with other investigators, the research scientist will work to formulate and prepare grant proposals as PI on grants. (10%).

3.       Conduct experiments involving colon cancer cell lines, colon cancer tissues and colon cancer mouse models including surgeries to established orthotopic and metastatic colon cancer models.  (50%).

4.       Perform metabolite tracing experiments in animal models (20%).

5.       Mentor postdoctoral fellows and graduate students (10%).



Perform other duties as assigned.



Supervise postdoctoral fellows and graduate students. Provide technical assistance and help to trouble shoot research problems.



Experience: Position requires a minimal of 10 years of experience in colon cancer research. Education/Licensing: A PhD in biological science.



The candidate must have the following technical skills: various molecular biology techniques including gene targeting, molecular cloning, western blot analysis, real-time PCR, ect; various cellular assays involving colon cancer cell lines; immunohistochemistry analysis of tumor tissues; establishment colon cancer subcutaneous and orthotopic xenograft models; developing and analyzing transgenic mice with intestinal tumors and stable isotope metabolite tracing.



The applicant will work with tissue cultured cells, mice and radioactive isotopes. 


Interested individuals should send a cover letter, CV, and the names/phone numbers of three people who could provide letters of reference by email to Michelle Yanick at


Case Western Reserve University provides reasonable accommodations to applicants with disabilities.  Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Inclusion, Diversity and Equal Opportunity at 216-368-8877 to request a reasonable accommodation.  Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.

In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity.  Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.