Senior Research Associate - Department of Nutrition

 

Title: Senior Research Associate

Department:  Department of Nutrition

Supervisor Name and Title:  Mark Chance, Ph.D. Professor

 

  1. Statement of research and scientific responsibilities

The responsibilities of this position include: planning and executing between 4-5 projects for the laboratory of Dr. Chance and his collaborators. In his/her collaborative relationships the SRA will be involved in experiment design for research projects related to quantitative and qualitative proteomics, sample preparation (digestion, phospho-peptides enrichment, and clean-up), data analysis  as well as helping preparing grant proposals and manuscripts. Specifically, this position requires experience and expertise with peptide LC-MS/MS data collection that will support high throughput discovery-proteomics. The suitable candidate will design and implement such projects independently. For collaborative research projects, the successful candidate will require broad research experience in experimental design, sample-preparation, biological mass spectrometry, proteomic data analysis and data interpretation as it pertains to the needs of discovery proteomics. The position requires good reporting ability, strong inter-personal skills and excellent communication skills. The candidate will be expected to multi-task strongly such that wet-lab work in relation to 4-5 projects and instrumentation tasks can be managed concurrently.  The SRA will also be responsible for developing new methodologies. Other duties include: setting up and running experiments on and maintaining a high-resolution LC-MS/MS instrument, trouble shooting instruments and training users.

  1. Technical skills

Development and discovery of new methodologies and validation of the existing approaches in proteomics using mass spectrometry.

Strong expertise in identification of post translational modifications of biological samples such as phosphorylation, glycosylation, deamidation, acetylation and methylation, etc.

Investigation of the structure and dynamics of proteins and their complex utilizing structural mass spectrometry such as the hydroxyl radical-mediated footprinting and hydrogen/deuterium exchange techniques, and light scattering techniques including static, dynamic, and electrophoresis light scatterings. 

 

  1. Supervisory Responsibilies

 

None

 

  1. education Requirements

PhD in Applied Biochemistry or related field

  1. Years of relevant experience Required

      At least 8 years of experience

      Multiple publications

  1. PROPOSED SALARYRANGE

$75,000

 

Interested applicants can send a copy of their CV to Joan Schenkel at jms114@case.edu.

 

 

Case Western Reserve University provides reasonable accommodations to applicants with disabilities.  Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Inclusion, Diversity and Equal Opportunity at 216-368-8877 to request a reasonable accommodation.  Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.

 

In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity.  Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.