Program Overview
Membership of the Immune-Oncology (IO) Program is composed of a diverse and multidisciplinary group of investigators with robust strength in immunogenetics, cellular and molecular immunology, oncoimmunology, and translational immunotherapeutics. IO investigators work collaboratively to investigate, discover and improve current and new immune-based therapeutics in an effort to overcome mechanisms of immune resistance and evasion by cancer cells, and creating paradigm-shifting discoveries in both preclinical and clinical realms - with each effort informing and complementing the other.
Specific Aims
- Elucidate the genetic and molecular mechanisms that control anti-tumor immunity and recognition of cancer cells by immune cells.
- Discover novel strategies to overcome acquired and/or adaptive immune resistance to immuno-oncology therapeutics.
- Develop clinical trials based on molecular, cellular and immune cancer therapeutic strategies.
Program Members
Ata Abbas, PhD
Research ScientistDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: axa335@case.edu
Phone: 216.368.1627
Derek Abbott, MD, PhD
ProfessorDepartment of PathologySchool of MedicineArline H. and Curtis F. Garvin Professor of MedicineDepartment of PathologySchool of MedicineProgram DirectorMedical Scientist Training ProgramSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: derek.abbott@case.edu
Phone: 216.368.8564
Stanley Adoro, PhD
Assistant ProfessorDepartment of PathologySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterMemberCleveland Center for Membrane & Structural BiologySchool of MedicineEmail: stanley.adoro@case.edu
Phone: 216.368.4712
Donald D. Anthony, Jr. , MD, PhD
ProfessorSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: DDA3@case.edu
Phone: 216.368.3540
Faiz Anwer, MD
Associate ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: anwerf@ccf.org
Stefanie Avril, MD
Associate ProfessorSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: stefanie.avril@case.edu
Phone: 216.844.3890
Tonjeh Bah, MD
Associate ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: tbah@metrohealth.org
Rose Chu Beck, MD, PhD
Associate ProfessorDepartment of PathologySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: rose.beck@uhhospitals.org
Phone: 216.844.8253
Brian Bolwell, MD
ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: bolwelb@ccf.org
G. Thomas Budd, MD
ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: buddg@ccf.org
Phone: 216.444.6480
Tatiana V. Byzova, PhD
Assistant ProfessorDepartment of Molecular MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: byzovat@ccf.org
Phone: 216.445.4312
Paolo F. Caimi, MD
Associate ProfessorDepartment of MedicineDivision of Hematology and OncologySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: paolo.caimi@case.edu
Mark Cameron, PhD
Associate ProfessorDepartment of Population and Quantitative Health SciencesSchool of MedicineMemberCenter for RNA Science and TherapeuticsSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterFacultyCleveland Institute for Computational BiologyEmail: mjc230@case.edu
Phone: 216.368.3196
Arnold I. Caplan, PhD
ProfessorDepartment of BiologyCollege of Arts and SciencesProfessorDepartment of PathologySchool of MedicineProfessorDepartment of Biomedical EngineeringCase School of EngineeringDirectorCenter for Modular Manufacturing of Structural TissuesMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: aic@case.edu
Phone: 216.368.3562
Hetty E. Carraway, MD, MBA
ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: carrawh@ccf.org
Phone: 216.445.5899
Timothy Chan, MD, PhD
Co-DirectorNational Center for Regenerative MedicineSchool of MedicineCo-LeaderImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: CHANT2@ccf.org
Gregory Cooper, MD
ProfessorDepartment of MedicineSchool of MedicineProfessorDepartment of Population and Quantitative Health SciencesSchool of MedicineCo-LeaderPopulation and Cancer Prevention ProgramCase Comprehensive Cancer CenterEmail: Gregory.Cooper@uhhospitals.org
Phone: 216.844.5385
Kevin D. Cooper, MD
ProfessorDepartment of DermatologySchool of MedicineProfessorDepartment of PathologySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: kevin.cooper@UHhospitals.org
Phone: 216.844.3111
Mari H. Dallas, MD
Associate ProfessorDepartment of PediatricsSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: mhd27@case.edu
Phone: 216.844.3345
Robert M. Dean, MD
Assistant ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: deanr@ccf.org
Phone: 216.445.5365
Amar Desai, PhD
Assistant ProfessorCase Comprehensive Cancer CenterMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: amar.desai@case.edu
C. Marcela Diaz, PhD
Adjunct Assistant ProfessorDepartment of Molecular MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: diazc2@ccf.org
James Driscoll, MD, PhD
Clinical Associate ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: james.driscoll@UHospitals.org
Phone: 216.368.0933
George R. Dubyak, PhD
ProfessorDepartment of Physiology and BiophysicsSchool of MedicineProfessorDepartment of PathologySchool of MedicineProfessorDepartment of PharmacologySchool of MedicineDirectorBiomedical Sciences Training ProgramSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: george.dubyak@case.edu
Phone: 216.368.5523
Robert L. Fairchild, PhD
ProfessorDepartment of Molecular MedicineSchool of MedicineProfessorDepartment of PathologySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: fairchr@ccf.org
Phone: 216.444.3146
Claudio Fiocchi, MD
ProfessorDepartment of Molecular MedicineSchool of MedicineProfessorDepartment of Inflammation and ImmunitySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: fiocchc@ccf.org
Phone: 216.445.0895
Molly Gallogly, MD, PhD
Assistant ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterBrian R. Gastman, MD
ProfessorDepartment of SurgerySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: gastmab@ccf.org
Phone: 216.444.2501
Stanton L. Gerson, MD
DeanSchool of MedicineSenior Vice President for Medical AffairsActing DirectorCase Comprehensive Cancer CenterDirectorNational Center for Regenerative MedicineProfessorDepartment of MedicineProfessorDepartment of Environmental Health SciencesMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: slg5@case.edu
Phone: 216.368.1994
Mahmoud Ghannoum, PhD
ProfessorDepartment of DermatologySchool of MedicineProfessorDepartment of PathologySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: mag3@case.edu
Phone: 216.844.8580
Brian T. Grimberg, PhD
Associate ProfessorDepartment of PathologySchool of MedicineDirector of Cytometry and Imaging ResearchCase Comprehensive Cancer CenterSchool of MedicineMemberImmune Oncology ProgramCenter for Global Health and DiseasesSchool of MedicineMemberDevelopmental Therapeutics ProgramCase Comprehensive Cancer CenterMemberHIV Co-Infections and Co-morbidities Working GroupCenter for AIDS ResearchEmail: endmalaria@case.edu
Phone: 216.368.6328
Neetu Gupta, PhD
Associate ProfessorDepartment of Molecular MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: guptan@ccf.org
Phone: 216.444.7455
Betty K. Hamilton, MD
Associate ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: hamiltb2@ccf.org
Phone: 216.445.7580
Clifford V. Harding, MD, PhD
Joseph R. Kahn Professor and Chair of PathologyDepartment of PathologySchool of MedicineInterim Department ChairDepartment of AnatomySchool of MedicineProfessorDepartment of AnatomySchool of MedicineProfessorDepartment of MedicineSchool of MedicineCo-DirectorMedical Scientist Training ProgramSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: cvh3@case.edu
Phone: 216.368.3611
Brian T. Hill, MD, PhD
Assistant ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: hillb2@ccf.org
Phone: 216.445.9451
Alex Y.C. Huang, MD, PhD
ProfessorDepartment of PediatricsSchool of MedicineProfessorDepartment of PathologySchool of MedicineCo-LeaderImmune Oncology ProgramCase Comprehensive Cancer CenterAssociate DirectorMedical Scientist Training ProgramSchool of MedicineEmail: ayh3@case.edu
Phone: 216.368.1271
Stanley Huang, PhD
Assistant ProfessorDepartment of PathologySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: stan.huang@case.edu
Phone: 216.368.3909
Deepa Jagadeesh, MD
Clinical Assistant ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: jagaded@ccf.org
David R. Kaplan, MD, PhD
Professor EmeritusDepartment of PathologySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: drk5@case.edu
Phone: 216.368.6590
Jack Khouri, MD
Assistant ProfessorDepartment of MedicineCleveland Clinic Lerner College of Medicine of Case Western Reserve UniversityMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: khourij@ccf.org
Xiaoxia Li , PhD
ProfessorDepartment of Molecular MedicineSchool of MedicineProfessorDepartment of PathologySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: lix@ccf.org
Phone: 216.445.8706
Navneet S. Majhail, MD, MS
ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: majhain@ccf.org
Phone: 216.444.2199
Ehsan Malek, MD
Assistant ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: ehsan.malek@UHhospitals.org
Suparna Mazumder, PhD
Assistant ProfessorDepartment of Molecular MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: mazumds@ccf.org
Phone: 216.444.0613
M. Edward Medof, MD, PhD
ProfessorDepartment of PathologySchool of MedicineProfessorDepartment of MedicineSchool of MedicineProfessorDepartment of Ophthalmology and Visual SciencesSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: m.medof@case.edu
Phone: 216.368.5434
Leland Metheny, MD
Assistant ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterHoward J. Meyerson, MD
ProfessorDepartment of PathologySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: howard.meyerson@case.edu
Phone: 216.844.1848
Sudipto Mukherjee, MD, MPH
Clinical Assistant ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: mukhers2@ccf.org
Phone: 216.444.0506
Folashade Otegbeye, MD, MPH
Assistant ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterPushpa Pandiyan, PhD
Associate ProfessorBiological SciencesSchool of Dental MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: pushpa.pandiyan@cwru.edu
Phone: 216.368.2939
Reshmi Parameswaran, MS, PhD
Assistant ProfessorDepartment of PathologySchool of MedicineAssistant ProfessorDepartment of PediatricsSchool of MedicineAssistant ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: rxp278@case.edu
Phone: 216.368.5697
Bhumika Patel, MD
MemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: patelb3@ccf.org
Phone: 216.444.8665
Nathan A. Pennell, MD, PhD
ProfessorDepartment of MedicineSchool of MedicineDeputy Associate Director for Clinical ResearchCase Comprehensive Cancer CenterMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: penneln@ccf.org
Phone: 216.445.9282
Brad L. Pohlman, MD
Clinical Assistant ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: pohlmab@ccf.org
Phone: 216.445.6070
Parameswaran Ramakrishnan, PhD, MS
Associate ProfessorDepartment of PathologySchool of MedicineAssistant ProfessorDepartment of BiochemistrySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterSchool of MedicineEmail: pxr150@case.edu
Phone: 216.368.2387
Ronald M. Sobecks, MD
Associate ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: sobeckr@ccf.org
Phone: 216.445.4626
Raghvendra Srivastava, PhD
Assistant ProfessorDepartment of MedicineCleveland Clinic Lerner College of Medicine of Case Western Reserve UniversityEmail: srivasr@ccf.org
William Tse, MD, MBA
Clinical ProfessorDepartment of MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: wtse@metrohealth.org
Phone: 216.778.3845
Vincent K. Tuohy, PhD
ProfessorDepartment of Molecular MedicineSchool of MedicineProfessorDepartment of PathologySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: tuohyv@ccf.org
Phone: 216.445.9684
Kristen VanHeyst, DO
Assistant ProfessorDepartment of PediatricsSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterDavid Wald, MD, PhD
Associate ProfessorDepartment of PathologySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterAssociate DirectorMedical Scientist Training ProgramSchool of MedicineEmail: david.wald@case.edu
Phone: 216.368.5668
Li Lily Wang, PhD
Clinical Associate ProfessorDepartment of Molecular MedicineSchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: wangl9@ccf.org
Phone: 216.973.5628
Stephanie G. Worrell, MD
Assistant ProfessorDepartment of SurgerySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterMei Zhang, PhD
Assistant ProfessorDepartment of Biomedical EngineeringCase School of EngineeringMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: mxz128@case.edu
Phone: 216.844.3098
Lan Zhou, MD, PhD
ProfessorDepartment of PathologySchool of MedicineVice Chair for ResearchDepartment of PathologySchool of MedicineMemberImmune Oncology ProgramCase Comprehensive Cancer CenterEmail: lan.zhou@case.edu
Phone: 216.368.1671