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Immune Oncology

Program Overview

Membership of the Immune-Oncology (IO) Program is composed of a diverse and multidisciplinary group of investigators with robust strength in immunogenetics, cellular and molecular immunology, oncoimmunology, and translational immunotherapeutics. IO investigators work collaboratively to investigate, discover and improve current and new immune-based therapeutics in an effort to overcome mechanisms of immune resistance and evasion by cancer cells, and creating paradigm-shifting discoveries in both preclinical and clinical realms - with each effort informing and complementing the other.

Specific Aims

  • Elucidate the genetic and molecular mechanisms that control anti-tumor immunity and recognition of cancer cells by immune cells.
  • Discover novel strategies to overcome acquired and/or adaptive immune resistance to immuno-oncology therapeutics.
  • Develop clinical trials based on molecular, cellular and immune cancer therapeutic strategies.

Program Members

  • Portrait of Ata Abbas

    Ata Abbas, PhD

    Research Scientist
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: axa335@case.edu

    Phone: 216.368.1627

  • Portrait of Derek Abbott

    Derek Abbott, MD, PhD

    Professor
    Department of Pathology
    School of Medicine
    Arline H. and Curtis F. Garvin Professor of Medicine
    Department of Pathology
    School of Medicine
    Program Director
    Medical Scientist Training Program
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: derek.abbott@case.edu

    Phone: 216.368.8564

  • Dr. Stanley Adoro

    Stanley Adoro, PhD

    Assistant Professor
    Department of Pathology
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center
    Member
    Cleveland Center for Membrane & Structural Biology
    School of Medicine

    Email: stanley.adoro@case.edu

    Phone: 216.368.4712

  • Donald Anthony

    Donald D. Anthony, Jr. , MD, PhD

    Professor
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: DDA3@case.edu

    Phone: 216.368.3540

  • Portrait of Faiz Anwer

    Faiz Anwer, MD

    Associate Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: anwerf@ccf.org

  • Dr. Stefanie Avril

    Stefanie Avril, MD

    Associate Professor
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: stefanie.avril@case.edu

    Phone: 216.844.3890

  • Portrait of Tonjeh M Bah outside in whitecoat

    Tonjeh Bah, MD

    Associate Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: tbah@metrohealth.org

  • Portrait of Rose Chu Beck

    Rose Chu Beck, MD, PhD

    Associate Professor
    Department of Pathology
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: rose.beck@uhhospitals.org

    Phone: 216.844.8253

  • Portrait of Brian Bolwell

    Brian Bolwell, MD

    Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: bolwelb@ccf.org

  • Portrait of G. Thomas Budd

    G. Thomas Budd, MD

    Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: buddg@ccf.org

    Phone: 216.444.6480

  • Portrait of Tatiana Byzova

    Tatiana V. Byzova, PhD

    Assistant Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: byzovat@ccf.org

    Phone: 216.445.4312

  • Portrait of Paolo Caimi

    Paolo F. Caimi, MD

    Associate Professor
    Department of Medicine
    Division of Hematology and Oncology
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: paolo.caimi@case.edu

  • Mark Cameron, PhD

    Mark Cameron, PhD

    Associate Professor
    Department of Population and Quantitative Health Sciences
    School of Medicine
    Member
    Center for RNA Science and Therapeutics
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center
    Faculty
    Cleveland Institute for Computational Biology

    Email: mjc230@case.edu

    Phone: 216.368.3196

  • Image of headshot of Arnold Caplan

    Arnold I. Caplan, PhD

    Professor
    Department of Biology
    College of Arts and Sciences
    Professor
    Department of Pathology
    School of Medicine
    Professor
    Department of Biomedical Engineering
    Case School of Engineering
    Director
    Center for Modular Manufacturing of Structural Tissues
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: aic@case.edu

    Phone: 216.368.3562

  • Portrait of Hetty Carraway blonde woman wearing dark jacket

    Hetty E. Carraway, MD, MBA

    Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: carrawh@ccf.org

    Phone: 216.445.5899

  • Portrait of Tim Chan

    Timothy Chan, MD, PhD

    Co-Director
    National Center for Regenerative Medicine
    School of Medicine
    Co-Leader
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: CHANT2@ccf.org

  • Portrait of Gregory Cooper

    Gregory Cooper, MD

    Professor
    Department of Medicine
    School of Medicine
    Professor
    Department of Population and Quantitative Health Sciences
    School of Medicine
    Co-Leader
    Population and Cancer Prevention Program
    Case Comprehensive Cancer Center

    Email: Gregory.Cooper@uhhospitals.org

    Phone: 216.844.5385

  • Portrait of Kevin Cooper in blue dress shirt, blue tie and white coat

    Kevin D. Cooper, MD

    Professor
    Department of Dermatology
    School of Medicine
    Professor
    Department of Pathology
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: kevin.cooper@UHhospitals.org

    Phone: 216.844.3111

  • Portrait of Mari Dallas

    Mari H. Dallas, MD

    Associate Professor
    Department of Pediatrics
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: mhd27@case.edu

    Phone: 216.844.3345

  • Robert Dean headshot

    Robert M. Dean, MD

    Assistant Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: deanr@ccf.org

    Phone: 216.445.5365

  • Portrait of Amar Desai

    Amar Desai, PhD

    Assistant Professor
    Case Comprehensive Cancer Center
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: amar.desai@case.edu

  • Portrait of C Marcela Diaz

    C. Marcela Diaz, PhD

    Adjunct Assistant Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: diazc2@ccf.org

  • Portrait of James Driscoll

    James Driscoll, MD, PhD

    Clinical Associate Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: james.driscoll@UHospitals.org

    Phone: 216.368.0933

  • George Dubyak

    George R. Dubyak, PhD

    Professor
    Department of Physiology and Biophysics
    School of Medicine
    Professor
    Department of Pathology
    School of Medicine
    Professor
    Department of Pharmacology
    School of Medicine
    Director
    Biomedical Sciences Training Program
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: george.dubyak@case.edu

    Phone: 216.368.5523

  • Robert Fairchild headshot

    Robert L. Fairchild, PhD

    Professor
    Department of Molecular Medicine
    School of Medicine
    Professor
    Department of Pathology
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: fairchr@ccf.org

    Phone: 216.444.3146

  • Claudio Fiocchi Cleveland Clinic headshot

    Claudio Fiocchi, MD

    Professor
    Department of Molecular Medicine
    School of Medicine
    Professor
    Department of Inflammation and Immunity
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: fiocchc@ccf.org

    Phone: 216.445.0895

  • Portrait of Molly Gallogly, MD, PhD

    Molly Gallogly, MD, PhD

    Assistant Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: molly.gallogly@UHhospitals.org

  • Portrait of Brian Gastman

    Brian R. Gastman, MD

    Professor
    Department of Surgery
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: gastmab@ccf.org

    Phone: 216.444.2501

  • Portrait of Stan Gerson in dark suit with light colored tie

    Stanton L. Gerson, MD

    Dean
    School of Medicine
    Senior Vice President for Medical Affairs
    Acting Director
    Case Comprehensive Cancer Center
    Director
    National Center for Regenerative Medicine
    Professor
    Department of Medicine
    Professor
    Department of Environmental Health Sciences
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: slg5@case.edu

    Phone: 216.368.1994

  • Portrait of Mahmoud Ghannoum

    Mahmoud Ghannoum, PhD

    Professor
    Department of Dermatology
    School of Medicine
    Professor
    Department of Pathology
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: mag3@case.edu

    Phone: 216.844.8580

  • Brian Grimberg headshot

    Brian T. Grimberg, PhD

    Associate Professor
    Department of Pathology
    School of Medicine
    Director of Cytometry and Imaging Research
    Case Comprehensive Cancer Center
    School of Medicine
    Member
    Immune Oncology Program
    Center for Global Health and Diseases
    School of Medicine
    Member
    Developmental Therapeutics Program
    Case Comprehensive Cancer Center
    Member
    HIV Co-Infections and Co-morbidities Working Group
    Center for AIDS Research

    Email: endmalaria@case.edu

    Phone: 216.368.6328

  • Portrait of Neetu Gupta

    Neetu Gupta, PhD

    Associate Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: guptan@ccf.org

    Phone: 216.444.7455

  • Portrait of Betty Hamilton

    Betty K. Hamilton, MD

    Associate Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: hamiltb2@ccf.org

    Phone: 216.445.7580

  • Dr. Clifford Harding

    Clifford V. Harding, MD, PhD

    Joseph R. Kahn Professor and Chair of Pathology
    Department of Pathology
    School of Medicine
    Interim Department Chair
    Department of Anatomy
    School of Medicine
    Professor
    Department of Anatomy
    School of Medicine
    Professor
    Department of Medicine
    School of Medicine
    Co-Director
    Medical Scientist Training Program
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: cvh3@case.edu

    Phone: 216.368.3611

  • Brian T. Hill, MD, PhD

    Assistant Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: hillb2@ccf.org

    Phone: 216.445.9451

  • Alex Huang, MD, PhD

    Alex Y.C. Huang, MD, PhD

    Professor
    Department of Pediatrics
    School of Medicine
    Professor
    Department of Pathology
    School of Medicine
    Co-Leader
    Immune Oncology Program
    Case Comprehensive Cancer Center
    Associate Director
    Medical Scientist Training Program
    School of Medicine

    Email: ayh3@case.edu

    Phone: 216.368.1271

  • Portrait of Stanley Huang sitting at a table

    Stanley Huang, PhD

    Assistant Professor
    Department of Pathology
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: stan.huang@case.edu

    Phone: 216.368.3909

  • Portrait of Deepa Jagadeesh

    Deepa Jagadeesh, MD

    Clinical Assistant Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: jagaded@ccf.org

  • Dr. David Kaplan

    David R. Kaplan, MD, PhD

    Professor Emeritus
    Department of Pathology
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: drk5@case.edu

    Phone: 216.368.6590

  • Portrait of Jack Khouri

    Jack Khouri, MD

    Assistant Professor
    Department of Medicine
    Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: khourij@ccf.org

  • Xiaoxia Li , PhD

    Professor
    Department of Molecular Medicine
    School of Medicine
    Professor
    Department of Pathology
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: lix@ccf.org

    Phone: 216.445.8706

  • Navneet S. Majhail, MD, MS

    Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: majhain@ccf.org

    Phone: 216.444.2199

  • Ehsan Malek, MD

    Assistant Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: ehsan.malek@UHhospitals.org

  • Suparna Mazumder, PhD

    Assistant Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: mazumds@ccf.org

    Phone: 216.444.0613

  • Dr. Edward Medof

    M. Edward Medof, MD, PhD

    Professor
    Department of Pathology
    School of Medicine
    Professor
    Department of Medicine
    School of Medicine
    Professor
    Department of Ophthalmology and Visual Sciences
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: m.medof@case.edu

    Phone: 216.368.5434

  • Portrait of Leland Metheny

    Leland Metheny, MD

    Assistant Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: leland.metheny@UHhospitals.org

  • Dr. Howard Meyerson

    Howard J. Meyerson, MD

    Professor
    Department of Pathology
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: howard.meyerson@case.edu

    Phone: 216.844.1848

  • Sudipto Mukherjee, MD, MPH

    Clinical Assistant Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: mukhers2@ccf.org

    Phone: 216.444.0506

  • Folashade Otegbeye, MD, MPH

    Assistant Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: folashade.otegbeye@UHhospitals.org

  • Pushpa Pandiyan

    Pushpa Pandiyan, PhD

    Associate Professor
    Biological Sciences
    School of Dental Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: pushpa.pandiyan@cwru.edu

    Phone: 216.368.2939

  • Portrait of Reshmi Parameswaran

    Reshmi Parameswaran, MS, PhD

    Assistant Professor
    Department of Pathology
    School of Medicine
    Assistant Professor
    Department of Pediatrics
    School of Medicine
    Assistant Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: rxp278@case.edu

    Phone: 216.368.5697

  • Portrait of Bhumika Patel

    Bhumika Patel, MD

    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: patelb3@ccf.org

    Phone: 216.444.8665

  • Portrait of Nathan Pennell

    Nathan A. Pennell, MD, PhD

    Professor
    Department of Medicine
    School of Medicine
    Deputy Associate Director for Clinical Research
    Case Comprehensive Cancer Center
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: penneln@ccf.org

    Phone: 216.445.9282

  • Portrait of Brad Pohlman

    Brad L. Pohlman, MD

    Clinical Assistant Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: pohlmab@ccf.org

    Phone: 216.445.6070

  • Dr. Parameswaran Ramakrishnan

    Parameswaran Ramakrishnan, PhD, MS

    Associate Professor
    Department of Pathology
    School of Medicine
    Assistant Professor
    Department of Biochemistry
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center
    School of Medicine

    Email: pxr150@case.edu

    Phone: 216.368.2387

  • Portrait of Ronald Sobecks

    Ronald M. Sobecks, MD

    Associate Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: sobeckr@ccf.org

    Phone: 216.445.4626

  • Raghvendra Srivastava, PhD

    Raghvendra Srivastava, PhD

    Assistant Professor
    Department of Medicine
    Cleveland Clinic Lerner College of Medicine of Case Western Reserve University

    Email: srivasr@ccf.org

  • William Tse in white labcoat

    William Tse, MD, MBA

    Clinical Professor
    Department of Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: wtse@metrohealth.org

    Phone: 216.778.3845

  • Portrait of Vincent Tuohy

    Vincent K. Tuohy, PhD

    Professor
    Department of Molecular Medicine
    School of Medicine
    Professor
    Department of Pathology
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: tuohyv@ccf.org

    Phone: 216.445.9684

  • Portrait of Kristen VanHeyst

    Kristen VanHeyst, DO

    Assistant Professor
    Department of Pediatrics
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: kristen.vanheyst@UHhospitals.org

  • Portrait of David Wald

    David Wald, MD, PhD

    Associate Professor
    Department of Pathology
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center
    Associate Director
    Medical Scientist Training Program
    School of Medicine

    Email: david.wald@case.edu

    Phone: 216.368.5668

  • Portrait of Li Lily Wang

    Li Lily Wang, PhD

    Clinical Associate Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: wangl9@ccf.org

    Phone: 216.973.5628

  • Portrait of Stephanie Worrell

    Stephanie G. Worrell, MD

    Assistant Professor
    Department of Surgery
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: stephanie.worrell@UHhospitals.org

  • Mei Zhang, PhD

    Assistant Professor
    Department of Biomedical Engineering
    Case School of Engineering
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: mxz128@case.edu

    Phone: 216.844.3098

  • Dr. Lan Zhou

    Lan Zhou, MD, PhD

    Professor
    Department of Pathology
    School of Medicine
    Vice Chair for Research
    Department of Pathology
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: lan.zhou@case.edu

    Phone: 216.368.1671