Annual Scientific Retreat Agenda

Thursday, JULY 22

All are welcome to attend. Please register to receive virtual retreat access.

12:00 – 12:15 PM

"Year of Accomplishments/Strategic Plan"
Stan Gerson, MD
Director, Case Comprehensive Cancer Center 

12:15 – 1:15

TED-style Talks

Diana Bilimoria, PhD
KeyBank Professor and Chair, Organizational Behavior, Weatherhead School of Management, Case Western Reserve University

Daniel E. Spratt, MD
Vincent K. Smith Chair in Radiation Oncology, Seidman Cancer Center, University Hospitals

Serpil Erzurum, MD
Chief Research & Academic Officer, Cleveland Clinic

1:15 – 1:25 Break
1:25 – 2:30

Session I: Metabolomics

Moderators: Abhishek Chakraborty, PhD
Planning Committee Member, Cancer Genomics Program, Case Comprehensive Cancer Center, Cleveland Clinic
Kristina Austin
Director of Community Engagement, Case Comprehensive Cancer Center

Alan Diehl, PhD
Deputy Director and Chief Operating Officer, Case Comprehensive Cancer Center

Trainee Invited Presentation: "Glioblastoma acquires mitochondria from the tumor microenvironment that augment tumorigenicity"
Dionysios Watson, MD, PhD
Mentor: Justin Lathia, PhD, Cleveland Clinic

"Malignant ER proteostasis in breast cancer"
Maria Hatzoglou, PhD 
Member, Molecular Oncology Program, Case Comprehensive Cancer Center

Panel/Q&A

2:30 – 4:00 Poster Session

Friday, JULY 23

Members and trainees only. Please register to receive virtual retreat access.

8:00 – 8:30 AM

"Strategic directions"
Stan Gerson, MD
Director, Case Comprehensive Cancer Center 

8:30 – 9:35

Session II: Therapeutic Translation

Moderators: Omar Mian, MD, PhD
Member, Developmental Therapeutics Program, Case Comprehensive Cancer Center, Cleveland Clinic
Francis Mills
Member, Community Advisory Board, Case Comprehensive Cancer Center
            
Jennifer Yu, MD, PhD
Co-Leader, Developmental Therapeutics Program, Case Comprehensive Cancer Center, Cleveland Clinic

Trainee Invited Presentation: ''Therapeutic targeting of protein disulfide isomerase PDIA1 in multiple myeloma"
Metis Hasipek, PhD
Mentor: Babal Jha, PhD, Cleveland Clinic

Derek Taylor, PhD
Member, Developmental Therapeutics Program, Case Comprehensive Cancer Center, Case Western Reserve University

Panel/Q & A

9:35 – 9:45 Break
9:45 – 10:50

Session III: Immuno-oncology

Moderators: Stanley Adoro, PhD
Planning Committee Member, Case Comprehensive Cancer Center, Case Western Reserve University
Michele Seyranian
Member, Community Advisory Board, Case Comprehensive Cancer Center

Mei Zhang, PhD
Member, Developmental Therapeutics Program, Case Comprehensive Cancer Center, Case Western Reserve University

Trainee Invited Presentation: "Sequential single-cell transcriptional and protein marker profiling reveals TIGIT as a marker of CD19 CAR-T cell dysfunction in patients with non-Hodgkin’s lymphoma"
Zachary Jackson, PhD
Mentor: David Wald, MD, PhD, University Hospitals

Brian Gastman, MD
Member, Immune Oncology Program, Case Comprehensive Cancer Center, Cleveland Clinic

Panel/Q & A

10:50 – 11:40

Keynote Presentation: "Sex bias in CD8+ T cell programming in the tumor microenvironment"

Zihai Li, MD, PhD
Founding Director, Pelotonia Institute for Immuno-Oncology and the Klotz Chair in Cancer Research, The Ohio State University

11:40 – 12:55

Research Program Breakouts

Registered attendees will be assigned to breakout rooms in Zoom for their programs.

12:55 – 2:00

Session IV: Local/Global Risks 

Moderators: Jennifer Cullen, PhD, MPH
Planning Committee Member, Associate Director for Cancer Population Sciences, Case Comprehensive Cancer Center, Case Western Reserve University 
Cheryl Davis
Member, Community Advisory Board, Case Comprehensive Cancer Center

Robert Salata, MD
Member, Population and Cancer Prevention Program, Case Comprehensive Cancer Center, University Hospitals

Trainee Invited Presentation: "Investigating geographic patterns of aggressive tumor subtypes: Integrating social and environmental mechanisms to understand biological outcomes"
Anna Miller, PhD
Mentor: Stefanie Avril, MD, University Hospitals

Kristine Zanotti, MD
Member, Population and Cancer Prevention Program, Case Comprehensive Cancer Center, University Hospitals

Panel/Q & A

2:00 – 2:10 Break
2:10 – 3:15

Session V: Epigenetics/Genetics

Moderators: Hanna Heemers, PhD
Member, Developmental Therapeutics Program, Case Comprehensive Cancer Center, Cleveland Clinic
Gina Chicotel
Member, Community Advisory Board, Case Comprehensive Cancer Center

Berkley Gryder, PhD
Assistant Professor, Case Comprehensive Cancer Center, Case Western Reserve University

Trainee Invited Presentation: "The extraction and validation of the Cisplatin Sensitivity Signature"
Jessica Scarborough, MS
Mentor: Jacob Scott, MD, PhD, Cleveland Clinic

Babal Jha, PhD
Member, Developmental Therapeutics Program, Case Comprehensive Cancer Center, Cleveland Clinic

Panel/Q & A

3:15 – 3:30 Wrap-up
3:30 – 4:30 Program Leaders/Executive Committee closed session