Innovators in AYA Cancer Agenda

Thursday, November 14, 2019
Tinkham Veale University Center
12:00-1:30pm Registration

Welcome and Introduction

Stan Gerson, MD
Case Comprehensive Cancer Center

John Letterio, MD
Case Western Reserve University/University Hospitals, Case Comprehensive Cancer Center    


SESSION I: Metastasis and Therapy Resistance in Sarcoma
Moderator: Alex Y. Huang, MD, PhD

"A Canine CAR Journey - Are We Almost There?"
Nicola Mason, B. Vet. Med, PhD, DACVIM (Internal Medicine)
PennVet Cancer Center

"Learning Signatures of Ewings Sarcoma Drug Sensitivity from Convergent Evolution: Experiments Motivated by Mathematical Models"
Jacob Scott, MD, DPhil
Cleveland Clinic, Case Comprehensive Cancer Center

"Targeting the Metastatic Epigenome of Osteosarcoma"
Peter Scacheri, PhD
Case Western Reserve University, Case Comprehensive Cancer Center

Panel Discussion

3:15-3:35pm Break

"Bedside to Bench: Lessons from a Cancer Survivor turned Researcher"
Elana Simon


"A Patient-Clinician-Research Partnership for the Development of Diagnostics and Therapeutics for a Childhood Cancer, Fibrolamellar Hepatocellular Carcinoma"
Sanford Simon, PhD
Rockefeller University

5:00-6:00pm Poster Session and Reception


Friday, November 15, 2019
Tinkham Veale University Center
8:00-8:30am Registration


Alex Y. Huang, MD, PhD
Case Western Reserve University/University Hospitals, Case Comprehensive Cancer Center 


SESSION II: Clinical Trials & Novel Therapies
Moderator: Matteo Trucco, MD

"Targeting Master Regulator Dependencies in Osteosarcoma"
Julia Glade Bender, MD
Memorial Sloan Kettering Cancer Center

"Count Me In: Partnering with Patients to Accelerate Discoveries"
Michael Dunphy
Broad Institute of MIT and Harvard

"Bone Seeking Radiopharmaceuticals for Metastatic Osteosarcoma"
David Loeb, MD, PhD
Albert Einstein College of Medicine

"Modeling and Targeting Metastatic Sarcomas"
Jason Yustein, MD, PhD
Dan L. Duncan Comprehensive Cancer Center/Baylor College of Medicine
Texas Children's Cancer Center

Panel Discussion

10:35-10:55am Break
10:55-11:55am SESSION III: Rising Stars
Moderators: Yamilet Huerta, MD and Kristen VanHeyst, DO


"Look for the Light"

Theresa Beech
Osteosarcoma Collaborative
Because of Daniel


SESSION IV: Policy & Advocacy/Lunch

"Harnessing Olivia: Rage, Love and AYA Cancer Advocacy"
Michael Egge, JD
Latham & Watkins

Simon Davies
Teen Cancer America

Nick & Angie Giallourakis
Elephants & Tea 

Danielle Leach
Alliance for Childhood Cancer

Panel Discussion

2:20-2:35 Break

SESSION V: Survivorship

"Key Challenges Facing Adolescents and Young Adults with Cancer: Survival, Toxicity and Clinical Trials"
David Freyer, DO, MS
University of Southern California/Children’s Hospital Los Angeles

"The Changing Regulatory Landscape and its Impact on the Pharmaceutical Industry’s Approaches to the Inclusion of Children/AYA Patients in Clinical Trials"
Mark Kieran, MD, PhD
Bristol-Myers Squibb

"Financial Challenges Faced by AYAs with Cancer"
Susan Parsons, MD, MRP
Tufts Medical Center

Panel Discussion

4:10-4:15pm Closing remarks