Member Publications

Cancer Related High Impact >10 Publications
(Jan 1, 2020-June 30, 2020)

*Cancer Center members in bold

Affronti HC, Rowsam AM, Pellerite AJ, Rosario SR, Long MD, Jacobi JJ, Bianchi-Smiraglia A, Boerlin CS, Gillard BM, Karasik E, Foster BA, Moser M, Wilton JH, Attwood K, Nikiforov MA, Azabdaftari G, Pili R, Phillips JG (DT), Casero RA, Smiraglia DJ. Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy. Nat Commun. 2020 JAN 07; 11(1):52. DOI: 10.1038/s41467-019-13950-4. 2020 Jan 7. PubMed PMID: 31911608; PMCID: PMC6946658.

Akhavanfard S, Padmanabhan R, Yehia L, Cheng F, Eng C (CPC). Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors. Nat Commun. 2020 MAY 05; 11(1):2206. DOI: 10.1038/s41467-020-16067-1. 2020 May 5. PubMed PMID: 32371905; PMCID: PMC7200683.

Ambrosone CB, Zirpoli GR, Hutson AD, McCann WE, McCann SE, Barlow WE, Kelly KM, Cannioto R, Sucheston-Campbell LE, Hershman DL, Unger JM, Moore HCF (CPC), Stewart JA, Isaacs C, Hobday TJ, Salim M, Hortobagyi GN, Gralow JR, Budd GT, Albain KS. Dietary Supplement Use During Chemotherapy and Survival Outcomes of Patients With Breast Cancer Enrolled in a Cooperative Group Clinical Trial (SWOG S0221). J. Clin. Oncol.. 2020 MAR 10; 38(8):804-814. DOI: 10.1200/JCO.19.01203. 2019 Dec 19. PubMed PMID: 31855498; PMCID: PMC7062457.

Archambault AN, Su YR, Jeon J, Thomas M, Lin Y, Conti DV, Win AK, Sakoda LC, Lansdorp-Vogelaar I, Peterse EF, Zauber AG, Duggan D, Holowatyj AN, Huyghe JR, Brenner H, Cotterchio M, Bézieau S, Schmit SL, Edlund CK, Southey MC, MacInnis RJ, Campbell PT, Chang-Claude J, Slattery ML, Chan AT, ...Markowitz SD (GICG)...Schumacher F (CPC)..., et al. Cumulative Burden of Colorectal Cancer-Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer. Gastroenterology. 2020 APR 01; 158(5):1274-1286.e12. DOI: 10.1053/j.gastro.2019.12.012. 2019 Dec 19. PubMed PMID: 31866242; PMCID: PMC7103489.

Ataca D, Aouad P, Constantin C, Laszlo C, Beleut M, Shamseddin M, Rajaram RD, Jeitziner R, Mead TJ, Caikovski M, Bucher P, Ambrosini G, Apte SS (MO), Brisken C. The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche. Nat Commun. 2020 MAR 26; 11(1):1571. DOI: 10.1038/s41467-020-15357-y. 2020 Mar 26. PubMed PMID: 32218432; PMCID: PMC7099066.

Balasubramanian SK, Sharma M, Venur VA, Schmitt P, Kotecha R, Chao ST (CI), Suh JH (DT), Angelov L (DT), Mohammadi AM, Vogelbaum MA, Barnett GH (DT), Jia X, Pennell NA (DT), Ahluwalia MS (DT). Impact of EGFR mutation and ALK rearrangement on the outcomes of non-small cell lung cancer patients with brain metastasis. Neuro-oncology. 2020 FEB 20; 22(2):267-277. DOI: 10.1093/neuonc/noz155. PubMed PMID: 31648302.

Bernhardt D, Wick W, Weiss SE, Sahgal A, Lo SS, Suh JH (DT), Chang EL, Foote M, Perry J, Meyer B, Vajkoczy P, Wen PY, Straube C, Pigorsch S, Wilkens JJ, Combs SE. Neuro-oncology Management During the COVID-19 Pandemic With a Focus on WHO Grade III and IV Gliomas. Neuro-oncology. 2020 MAY 05; . DOI: 10.1093/neuonc/noaa113. 2020 May 5. PubMed PMID: 32369601; PMCID: PMC7239150.

Billi AC, Ludwig JE, Fritz Y, Rozic R, Swindell WR, Tsoi LC, Gruszka D, Abdollahi-Roodsaz S, Xing X, Diaconu D, Uppala R, Camhi MI, Klenotic PA, Sarkar MK, Husni ME, Scher JU, McDonald C (MO), Kahlenberg JM, Midura RJ, Gudjonsson JE, Ward NL. KLK6 expression in skin induces PAR1-mediated psoriasiform dermatitis and inflammatory joint disease. J. Clin. Invest.. 2020 JUN 01; 130(6):3151-3157. DOI: 10.1172/JCI133159. PubMed PMID: 32155135; PMCID: PMC7260032.

Brudno JN, Lam N, Vanasse D, Shen YW, Rose JJ, Rossi J, Xue A, Bot A, Scholler N, Mikkilineni L, Roschewski M, Dean R (HICB), Cachau R, Youkharibache P, Patel R, Hansen B, Stroncek DF, Rosenberg SA, Gress RE, Kochenderfer JN. Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma. Nat. Med.. 2020 FEB 01; 26(2):270-280. DOI: 10.1038/s41591-019-0737-3. 2020 Jan 20. PubMed PMID: 31959992.

Cannioto RA, Hutson A, Dighe S, McCann W, McCann SE, Zirpoli GR, Barlow W, Kelly KM, DeNysschen CA, Hershman DL, Unger JM, Moore HCF (CPC), Stewart JA, Isaacs C, Hobday TJ, Salim M, Hortobagyi GN, Gralow JR, Albain KS, Budd GT, Ambrosone CB. Physical activity before, during and after chemotherapy for high-risk breast cancer: relationships with survival. J. Natl. Cancer Inst.. 2020 APR 02; . DOI: 10.1093/jnci/djaa046. 2020 Apr 2. PubMed PMID: 32239145.

Chaturvedi S, Braunstein EM, Yuan X, Yu J, Alexander A, Chen H, Gavriilaki E, Alluri RK, Streiff MB, Petri M, Crowther MA, McCrae KR (HICB), Brodsky RA. Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS. Blood. 2020 JAN 23; 135(4):239-251. DOI: 10.1182/blood.2019003863. PubMed PMID: 31812994; PMCID: PMC6978159.

Chen J, He R, Sun W, Gao R, Peng Q, Zhu L, Du Y, Ma X, Guo X, Zhang H, Tan C, Wang J, Zhang W, Weng X, Man J, Bauer H, Wang QK, Martin BN, Zhang CJ, Li X (HICB), Wang C. TAGAP instructs Th17 differentiation by bridging Dectin activation to EPHB2 signaling in innate antifungal response. Nat Commun. 2020 APR 20; 11(1):1913. DOI: 10.1038/s41467-020-15564-7. 2020 Apr 20. PubMed PMID: 32312989; PMCID: PMC7171161.

Cines DB, Zaitsev S, Rauova L, Rux AH, Stepanova V, Krishnaswamy S, Sarkar A, Kowalska MA, Zhao G, Mast AE, Blumberg LJ, McCrae KR (HICB), Poncz M, Hubbard JJ, Pyzik M, Blumberg RS. FcRn augments induction of tissue factor activity by IgG-containing immune complexes. Blood. 2020 JUN 04; 135(23):2085-2093. DOI: 10.1182/blood.2019001133. PubMed PMID: 32187355; PMCID: PMC7273830.

Davatzikos C, Barnholtz-Sloan JS (CPC), Bakas S, Colen R, Mahajan A, Quintero CB, Font JC, Puig J, Jain R, Sloan AE (CI, DT), Badve C (CI), Marcus DS, Choi YS, Lee SK, Chang JH, Poisson LM, Griffith B, Dicker AP, Flanders AE, Booth TC, Rathore S, Akbari H, Sako C, Bilello M, Shukla G, et al. AI-based prognostic imaging biomarkers for precision neuro-oncology: the ReSPOND consortium. Neuro-oncology. 2020 JUN 09; 22(6):886-888. DOI: 10.1093/neuonc/noaa045. PubMed PMID: 32152622; PMCID: PMC7283022.

Davis FG, Smith TR, Gittleman HR, Ostrom QT, Kruchko C, Barnholtz-Sloan JS (CPC). Glioblastoma incidence rate trends in Canada and the United States compared with England, 1995-2015. Neuro-oncology. 2020 FEB 20; 22(2):301-302. DOI: 10.1093/neuonc/noz203. PubMed PMID: 31786602; PMCID: PMC7032629.

de Las Rivas M, Paul Daniel EJ, Narimatsu Y, Compañón I, Kato K, Hermosilla P, Thureau A, Ceballos-Laita L, Coelho H, Bernadó P, Marcelo F, Hansen L, Maeda R, Lostao A, Corzana F, Clausen H, Gerken TA (HICB), Hurtado-Guerrero R. Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3. Nat. Chem. Biol.. 2020 MAR 01; 16(3):351-360. DOI: 10.1038/s41589-019-0444-x. 2020 Jan 13. PubMed PMID: 31932717.

Dudiki T, Meller J, Mahajan G, Liu H, Zhevlakova I, Stefl S, Witherow C, Podrez E, Kothapalli CR, Byzova TV (GU). Microglia control vascular architecture via a TGFβ1 dependent paracrine mechanism linked to tissue mechanics. Nat Commun. 2020 FEB 20; 11(1):986. DOI: 10.1038/s41467-020-14787-y. 2020 Feb 20. PubMed PMID: 32080187; PMCID: PMC7033106.

Eggener SE, Rumble RB, Armstrong AJ, Morgan TM, Crispino T, Cornford P, van der Kwast T, Grignon DJ, Rai AJ, Agarwal N, Klein EA (GU), Den RB, Beltran H. Molecular Biomarkers in Localized Prostate Cancer: ASCO Guideline. J. Clin. Oncol.. 2020 MAY 01; 38(13):1474-1494. DOI: 10.1200/JCO.19.02768. 2019 Dec 12. PubMed PMID: 31829902.

Evonuk KS, Doyle RE, Moseley CE, Thornell IM, Adler K, Bingaman AM, Bevensee MO, Weaver CT, Min B (HICB), DeSilva TM. Reduction of AMPA receptor activity on mature oligodendrocytes attenuates loss of myelinated axons in autoimmune neuroinflammation. Sci Adv. 2020 JAN 01; 6(2):eaax5936. DOI: 10.1126/sciadv.aax5936. 2020 Jan 8. PubMed PMID: 31934627; PMCID: PMC6949032.

Fan X, McCullough RL, Huang E, Bellar A, Kim A, Poulsen KL, McClain CJ, Mitchell M, McCullough AJ, Radaeva S, Barton B, Szabo G, Dasarathy S (MO), Rotroff DM, Nagy LE. Diagnostic and Prognostic Significance of Complement in Patients with Alcohol-associated Hepatitis. Hepatology. 2020 JUN 17; . DOI: 10.1002/hep.31419. 2020 Jun 17. PubMed PMID: 32557728.

Fenaux P, Platzbecker U, Mufti GJ, Garcia-Manero G, Buckstein R, Santini V, Díez-Campelo M, Finelli C, Cazzola M, Ilhan O, Sekeres MA (HICB), Falantes JF, Arrizabalaga B, Salvi F, Giai V, Vyas P, Bowen D, Selleslag D, DeZern AE, Jurcic JG, Germing U, Götze KS, Quesnel B, Beyne-Rauzy O, Cluzeau T, et al. Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes. N. Engl. J. Med.. 2020 JAN 09; 382(2):140-151. DOI: 10.1056/NEJMoa1908892. PubMed PMID: 31914241.

Flaherty KT, Gray R, Chen A, Li S, Patton D, Hamilton SR, Williams PM, Mitchell EP, Iafrate AJ, Sklar J, Harris LN, McShane LM, Rubinstein LV, Sims DJ, Routbort M, Coffey B, Fu T, Zwiebel JA, Little RF, Marinucci D, Catalano R, Magnan R, Kibbe W, Weil C, Tricoli JV, ...Caimi P (HICB) ... et al. The Molecular Analysis for Therapy Choice (NCI-MATCH) Trial: Lessons for Genomic Trial Design. J. Natl. Cancer Inst.. 2020 JAN 10; . DOI: 10.1093/jnci/djz245. 2020 Jan 10. PubMed PMID: 31922567.

Fong L, Hotson A, Powderly J, Sznol M, Heist RS, Choueiri TK, George S, Hughes BG, Hellmann MD, Shepard DR (DT), Rini BI, Kummar S, Weise AM, Riese MJ, Markman B, Emens LA, Mahadevan D, Luke JJ, Laport G, Brody JD, Hernandez-Aya L, Bonomi P, Goldman JW, Berim L, Renouf DJ, et al. Adenosine 2A Receptor Blockade as an Immunotherapy for Treatment-Refractory Renal Cell Cancer. Cancer Discov. 2020 JAN 01; 10(1):40-53. DOI: 10.1158/2159-8290.CD-19-0980. 2019 Nov 15. PubMed PMID: 31732494; PMCID: PMC6954326.

Galsky MD, Mortazavi A, Milowsky MI, George S, Gupta S, Fleming MT, Dang LH, Geynisman DM, Walling R, Alter RS, Kassar M, Wang J, Gupta S (GU), Davis N, Picus J, Philips G, Quinn DI, Haines GK, Hahn NM, Zhao Q, Yu M, Pal SK. Randomized Double-Blind Phase II Study of Maintenance Pembrolizumab Versus Placebo After First-Line Chemotherapy in Patients With Metastatic Urothelial Cancer. J. Clin. Oncol.. 2020 JUN 01; 38(16):1797-1806. DOI: 10.1200/JCO.19.03091. 2020 Apr 9. PubMed PMID: 32271672; PMCID: PMC7255983.

Gittleman H, Sloan AE (CI), Barnholtz-Sloan JS (CPC). An independently validated survival nomogram for lower-grade glioma. Neuro-oncology. 2020 MAY 15; 22(5):665-674. DOI: 10.1093/neuonc/noz191. PubMed PMID: 31621885; PMCID: PMC7229246.

Grossman SA, Romo CG, Rudek MA, Supko J, Fisher J, Nabors LB, Wen PY, Peereboom DM (DT), Ellingson BM, Elmquist W, Barker FG, Kamson D, Sarkaria JN, Timmer W, Bindra RS, Ye X. Baseline Requirements for Novel Agents Being Considered for Phase II/III Brain Cancer Efficacy Trials: Conclusions from the Adult Brain Tumor Consortium's First Workshop on CNS Drug Delivery. Neuro-oncology. 2020 JUN 07; . DOI: 10.1093/neuonc/noaa142. 2020 Jun 7. PubMed PMID: 32506123.

Han X, Hofmann L, de la Fuente M, Alexander N, Palczewski K, Invent Consortium I, Nieman MT (MO). PAR4 activation involves extracellular loop-3 and transmembrane residue Thr153. Blood. 2020 JUN 23; . DOI: 10.1182/blood.2019004634. 2020 Jun 23. PubMed PMID: 32575122.

Hearn JWD, Sweeney CJ, Almassi N, Reichard CA, Reddy CA, Li H, Hobbs B, Jarrard DF, Chen YH, Dreicer R, Garcia JA (GU), Carducci MA, DiPaola RS, Sharifi N (GU). HSD3B1 Genotype and Clinical Outcomes in Metastatic Castration-Sensitive Prostate Cancer. JAMA Oncol. 2020 FEB 13; :e196496. DOI: 10.1001/jamaoncol.2019.6496. 2020 Feb 13. PubMed PMID: 32053149; PMCID: PMC7042830.

Henke PK, Kahn SR, Pannucci CJ, Secemksy EA, Evans NS, Khorana AA (DT), Creager MA, Pradhan AD. Call to Action to Prevent Venous Thromboembolism in Hospitalized Patients: A Policy Statement From the American Heart Association. Circulation. 2020 JUN 16; 141(24):e914-e931. DOI: 10.1161/CIR.0000000000000769. 2020 May 7. PubMed PMID: 32375490.

Hong DS, DuBois SG, Kummar S, Farago AF, Albert CM, Rohrberg KS, van Tilburg CM, Nagasubramanian R, Berlin JD, Federman N, Mascarenhas L, Geoerger B, Dowlati A (DT), Pappo AS, Bielack S, Doz F, McDermott R, Patel JD, Schilder RJ, Tahara M, Pfister SM, Witt O, Ladanyi M, Rudzinski ER, Nanda S, et al. Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1/2 clinical trials. Lancet Oncol.. 2020 APR 01; 21(4):531-540. DOI: 10.1016/S1470-2045(19)30856-3. 2020 Feb 24. PubMed PMID: 32105622.

Jewer M, Lee L, Leibovitch M, Zhang G, Liu J, Findlay SD, Vincent KM, Tandoc K, Dieters-Castator D, Quail DF, Dutta I, Coatham M, Xu Z, Puri A, Guan BJ, Hatzoglou M (MO), Brumwell A, Uniacke J, Patsis C, Koromilas A, Schueler J, Siegers GM, Topisirovic I, Postovit LM. Translational control of breast cancer plasticity. Nat Commun. 2020 MAY 19; 11(1):2498. DOI: 10.1038/s41467-020-16352-z. 2020 May 19. PubMed PMID: 32427827; PMCID: PMC7237473.

Kaira BG, Slater A, McCrae KR (HICB), Dreveny I, Sumya UM, Mutch NJ, Searle M, Emsley J. Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery. Blood. 2020 JUN 19; . DOI: 10.1182/blood.2020004818. 2020 Jun 19. PubMed PMID: 32559765.

Kang H, Stiles WR, Baek Y, Nomura S, Bao K, Hu S, Park GK, Jo MJ, I H, Coll JL, Rubin BP (GICG), Choi HS. Renal Clearable Theranostic Nanoplatforms for Gastrointestinal Stromal Tumors. Adv. Mater. Weinheim. 2020 FEB 01; 32(6):e1905899. DOI: 10.1002/adma.201905899. 2019 Dec 18. PubMed PMID: 31854033; PMCID: PMC7015778.

Kapoor PM, Mavaddat N, Choudhury PP, Wilcox AN, Lindström S, Behrens S, Michailidou K, Dennis J, Bolla MK, Wang Q, Jung A, Abu-Ful Z, Ahearn T, Andrulis IL, Anton-Culver H, Arndt V, Aronson KJ, Auer PL, Freeman LEB, Becher H, Beckmann MW, Beeghly-Fadiel A, Benitez J, Bernstein L, Bojesen SE, ...Schumacher F (CPC)...et al. Combined associations of a polygenic risk score and classical risk factors with breast cancer risk. J. Natl. Cancer Inst.. 2020 MAY 02; . DOI: 10.1093/jnci/djaa056. 2020 May 2. PubMed PMID: 32359158.

Karmakar M, Minns M, Greenberg EN, Diaz-Aponte J, Pestonjamasp K, Johnson JL, Rathkey JK, Abbott DW (HICB), Wang K, Shao F, Catz SD, Dubyak GR (HICB), Pearlman E. N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis. Nat Commun. 2020 MAY 05; 11(1):2212. DOI: 10.1038/s41467-020-16043-9. 2020 May 5. PubMed PMID: 32371889; PMCID: PMC7200749.

Knarr M, Avelar RA, Sekhar SC, Kwiatkowski LJ, Dziubinski ML, McAnulty J, Skala S, Avril S (HICB), Drapkin R, DiFeo A. miR-181a initiates and perpetuates oncogenic transformation through the regulation of innate immune signaling. Nat Commun. 2020 JUN 26; 11(1):3231. DOI: 10.1038/s41467-020-17030-w. 2020 Jun 26. PubMed PMID: 32591511; PMCID: PMC7320168.

Kondratova AA, Cheon H, Dong B, Holvey-Bates EG, Hasipek M, Taran I, Gaughan C, Jha BK (DT), Silverman RH (GU), Stark GR (GU, MO). Suppressing PARylation by 2',5'-oligoadenylate synthetase 1 inhibits DNA damage-induced cell death. EMBO J.. 2020 JUN 02; 39(11):e101573. DOI: 10.15252/embj.2019101573. 2020 Apr 23. PubMed PMID: 32323871; PMCID: PMC7265237.

Kuderer NM, Choueiri TK, Shah DP, Shyr Y, Rubinstein SM, Rivera DR, Shete S, Hsu CY, Desai A, de Lima Lopes G, Grivas P, Painter CA, Peters S, Thompson MA, Bakouny Z, Batist G, Bekaii-Saab T, Bilen MA, Bouganim N, Larroya MB, Castellano D, Del Prete SA, Doroshow DB, Egan PC, Elkrief A, ...Gupta S (GU)...Pennel N (DT)... et al. Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study. Lancet. 2020 JUN 20; 395(10241):1907-1918. DOI: 10.1016/S0140-6736(20)31187-9. 2020 May 28. PubMed PMID: 32473681; PMCID: PMC7255743.

Lee EQ, Weller M, Sul J, Bagley SJ, Sahebjam S, van den Bent M, Ahluwalia M (DT), Campian JL, Galanis E, Gilbert MR, Holdhoff M, Lesser GJ, Lieberman FS, Mehta MP, Penas-Prado M, Schreck KC, Strowd RE, Vogelbaum MA, Walbert T, Chang SM, Nabors LB, Grossman S, Reardon DA, Wen PY. Optimizing eligibility criteria and clinical trial conduct to enhance clinical trial participation for primary brain tumor patients. Neuro-oncology. 2020 MAY 15; 22(5):601-612. DOI: 10.1093/neuonc/noaa015. PubMed PMID: 31974566; PMCID: PMC7229255.

Lee YR, Yehia L, Kishikawa T, Ni Y, Leach B, Zhang J, Panch N, Liu J, Wei W, Eng C (CPC), Pandolfi PP. WWP1 Gain-of-Function Inactivation of PTEN in Cancer Predisposition. N. Engl. J. Med.. 2020 MAY 28; 382(22):2103-2116. DOI: 10.1056/NEJMoa1914919. PubMed PMID: 32459922.

Leonard D, Huang W, Izadmehr S, O'Connor CM, Wiredja DD, Wang Z, Zaware N, Chen Y, Schlatzer DM, Kiselar J, Vasireddi N, Schüchner S, Perl AL, Galsky MD, Xu W, Brautigan DL, Ogris E, Taylor DJ (DT), Narla G. Selective PP2A Enhancement through Biased Heterotrimer Stabilization. Cell. 2020 APR 30; 181(3):688-701.e16. DOI: 10.1016/j.cell.2020.03.038. 2020 Apr 20. PubMed PMID: 32315618; PMCID: PMC7243596.

Liao Y, Zhao J, Bulek K, Tang F, Chen X, Cai G, Jia S, Fox PL (MO), Huang E (GICG), Pizarro TT, Kalady MF (GICG), Jackson MW (MO), Bao S (MO), Sen GC (MO), Stark GR (MO), Chang CJ, Li X (HICB). Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis. Nat Commun. 2020 FEB 14; 11(1):900. DOI: 10.1038/s41467-020-14698-y. 2020 Feb 14. PubMed PMID: 32060280; PMCID: PMC7021685.

Liu G, Kolodziej C, Jin R, Qi S, Lou Y, Chen J, Jiang D, Zhao Y, Burda C (DT). MoS2-Stratified CdS-Cu2-xS Core-Shell Nanorods for Highly Efficient Photocatalytic Hydrogen Production. ACS Nano. 2020 MAY 26; 14(5):5468-5479. DOI: 10.1021/acsnano.9b09470. 2020 May 1. PubMed PMID: 32323971.

Lonial S, Jacobus S, Fonseca R, Weiss M, Kumar S, Orlowski RZ, Kaufman JL, Yacoub AM, Buadi FK, O'Brien T (DT), Matous JV, Anderson DM, Emmons RV, Mahindra A, Wagner LI, Dhodapkar MV, Rajkumar SV. Randomized Trial of Lenalidomide Versus Observation in Smoldering Multiple Myeloma. J. Clin. Oncol.. 2020 APR 10; 38(11):1126-1137. DOI: 10.1200/JCO.19.01740. 2019 Oct 25. PubMed PMID: 31652094; PMCID: PMC7145586.

Loomba R, Neuschwander-Tetri BA, Sanyal A, Chalasani N, Diehl AM, Terrault N, Kowdley K, Dasarathy S (MO), Kleiner D, Behling C, Lavine J, Van Natta M, Middleton M, Tonascia J, Sirlin C. Multicenter validation of association between decline in MRI-PDFF and histologic response in nonalcoholic steatohepatitis. Hepatology. 2020 JAN 21; . DOI: 10.1002/hep.31121. 2020 Jan 21. PubMed PMID: 31965579.

Luo H, Yu Q, Liu Y, Tang M, Liang M, Zhang D, Xiao TS (HICB), Wu L, Tan M, Ruan Y, Bungert J, Lu J. LATS kinase-mediated CTCF phosphorylation and selective loss of genomic binding. Sci Adv. 2020 FEB 01; 6(8):eaaw4651. DOI: 10.1126/sciadv.aaw4651. 2020 Feb 19. PubMed PMID: 32128389; PMCID: PMC7030924.

Mahameed M, Boukeileh S, Obiedat A, Darawshi O, Dipta P, Rimon A, McLennan G (CI), Fassler R, Reichmann D, Karni R, Preisinger C, Wilhelm T, Huber M, Tirosh B. Pharmacological induction of selective endoplasmic reticulum retention as a strategy for cancer therapy. Nat Commun. 2020 MAR 11; 11(1):1304. DOI: 10.1038/s41467-020-15067-5. 2020 Mar 11. PubMed PMID: 32161259; PMCID: PMC7066181.

Markham MJ, Wachter K, Agarwal N, Bertagnolli MM, Chang SM, Dale W, Diefenbach CSM, Rodriguez-Galindo C, George DJ, Gilligan TD (DT), Harvey RD, Johnson ML, Kimple RJ, Knoll MA, LoConte N, Maki RG, Meisel JL, Meyerhardt JA, Pennell NA (DT), Rocque GB, Sabel MS, Schilsky RL, Schneider BJ, Tap WD, Uzzo RG, et al. Clinical Cancer Advances 2020: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology. J. Clin. Oncol.. 2020 APR 01; 38(10):1081. DOI: 10.1200/JCO.19.03141. 2020 Feb 4. PubMed PMID: 32013670.

Mehta RS, Holtan SG, Wang T, Hemmer MT, Spellman SR, Arora M, Couriel DR, Alousi AM, Pidala J, Abdel-Azim H, Agrawal V, Ahmed I, Al-Homsi AS, Aljurf M, Antin JH, Askar M, Auletta JJ, Bhatt VR, Chee L, Chhabra S, Daly A, DeFilipp Z, Gajewski J, Gale RP, Gergis U, Majhail NS (HICB)... et al. Composite GRFS and CRFS Outcomes After Adult Alternative Donor HCT. J. Clin. Oncol.. 2020 JUN 20; 38(18):2062-2076. DOI: 10.1200/JCO.19.00396. 2020 May 4. PubMed PMID: 32364845; PMCID: PMC7302955.

Molinaro AM, Hervey-Jumper S, Morshed RA, Young J, Han SJ, Chunduru P, Zhang Y, Phillips JJ, Shai A, Lafontaine M, Crane J, Chandra A, Flanigan P, Jahangiri A, Cioffi G, Ostrom Q, Anderson JE, Badve C (CI), Barnholtz-Sloan J (CPC), Sloan AE (CI), Erickson BJ, Decker PA, Kosel ML, LaChance D, Eckel-Passow J, et al. Association of Maximal Extent of Resection of Contrast-Enhanced and Non-Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma. JAMA Oncol. 2020 FEB 06; . DOI: 10.1001/jamaoncol.2019.6143. 2020 Feb 6. PubMed PMID: 32027343; PMCID: PMC7042822.

Nanavaty V, Abrash EW, Hong C, Park S, Fink EE, Li Z, Sweet TJ, Bhasin JM, Singuri S, Lee BH (GU), Hwang TH (GU), Ting AH (GU). DNA Methylation Regulates Alternative Polyadenylation via CTCF and the Cohesin Complex. Mol. Cell. 2020 MAY 21; 78(4):752-764.e6. DOI: 10.1016/j.molcel.2020.03.024. 2020 Apr 24. PubMed PMID: 32333838; PMCID: PMC7245569.

NandyMazumdar M, Yin S, Paranjapye A, Kerschner JL, Swahn H, Ge A, Leir SH, Harris A (GU). Looping of upstream cis-regulatory elements is required for CFTR expression in human airway epithelial cells. Nucleic Acids Res.. 2020 APR 17; 48(7):3513-3524. DOI: 10.1093/nar/gkaa089. PubMed PMID: 32095812; PMCID: PMC7144911.

Nastoupil LJ, Jain MD, Feng L, Spiegel JY, Ghobadi A, Lin Y, Dahiya S, Lunning M, Lekakis L, Reagan P, Oluwole O, McGuirk J, Deol A, Sehgal AR, Goy A, Hill BT (HICB), Vu K, Andreadis C, Munoz J, Westin J, Chavez JC, Cashen A, Bennani NN, Rapoport AP, Vose JM, et al. Standard-of-Care Axicabtagene Ciloleucel for Relapsed or Refractory Large B-Cell Lymphoma: Results From the US Lymphoma CAR T Consortium. J. Clin. Oncol.. 2020 MAY 13; :JCO1902104. DOI: 10.1200/JCO.19.02104. 2020 May 13. PubMed PMID: 32401634.

Nemet I, Saha PP, Gupta N, Zhu W, Romano KA, Skye SM, Cajka T, Mohan ML, Li L, Wu Y, Funabashi M, Ramer-Tait AE, Naga Prasad SV, Fiehn O, Rey FE, Tang WHW, Fischbach MA, DiDonato JA (GU), Hazen SL. A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors. Cell. 2020 MAR 05; 180(5):862-877.e22. DOI: 10.1016/j.cell.2020.02.016. PubMed PMID: 32142679; PMCID: PMC7402401.

Palomo L, Meggendorfer M, Hutter S, Twardziok S, Adema V, Fuhrmann I, Fuster-Tormo F, Xicoy B, Zamora L, Acha P, Kerr CM, Kern W, Maciejewski JP (HICB), Solé F, Haferlach C, Haferlach T. Molecular landscape and clonal architecture of adult myelodysplastic/myeloproliferative neoplasms. Blood. 2020 JUN 23; . DOI: 10.1182/blood.2019004229. 2020 Jun 23. PubMed PMID: 32573691.

Papadimitriou N, Dimou N, Tsilidis KK, Banbury B, Martin RM, Lewis SJ, Kazmi N, Robinson TM, Albanes D, Aleksandrova K, Berndt SI, Timothy Bishop D, Brenner H, Buchanan DD, Bueno-de-Mesquita B, Campbell PT, Castellví-Bel S, Chan AT, Chang-Claude J, Ellingjord-Dale M, Figueiredo JC, Gallinger SJ, Giles GG, Giovannucci E, Gruber SB, ...Markowitz SD (GICG)... et al. Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis. Nat Commun. 2020 JAN 30; 11(1):597. DOI: 10.1038/s41467-020-14389-8. 2020 Jan 30. PubMed PMID: 32001714; PMCID: PMC6992637.

Puduvalli VK, Wu J, Yuan Y, Armstrong TS, Vera E, Wu J, Xu J, Giglio P, Colman H, Walbert T, Raizer J, Groves MD, Tran D, Iwamoto F, Avgeropoulos N, Paleologos N, Fink K, Peereboom D (DT), Chamberlain M, Merrell R, Penas Prado M, Yung WKA, Gilbert MR. A Bayesian Adaptive Randomized Phase II Multicenter Trial of Bevacizumab with or without Vorinostat in Adults with Recurrent Glioblastoma. Neuro-oncology. 2020 MAR 13; . DOI: 10.1093/neuonc/noaa062. 2020 Mar 13. PubMed PMID: 32166308.

Ramirez DG, Abenojar E, Hernandez C, Lorberbaum DS, Papazian LA, Passman S, Pham V, Exner AA (CI), Benninger RKP. Contrast-enhanced ultrasound with sub-micron sized contrast agents detects insulitis in mouse models of type1 diabetes. Nat Commun. 2020 MAY 07; 11(1):2238. DOI: 10.1038/s41467-020-15957-8. 2020 May 7. PubMed PMID: 32382089; PMCID: PMC7206014.

Reardon DA, Brandes AA, Omuro A, Mulholland P, Lim M, Wick A, Baehring J, Ahluwalia MS (DT), Roth P, Bähr O, Phuphanich S, Sepulveda JM, De Souza P, Sahebjam S, Carleton M, Tatsuoka K, Taitt C, Zwirtes R, Sampson J, Weller M. Effect of Nivolumab vs Bevacizumab in Patients With Recurrent Glioblastoma: The CheckMate 143 Phase 3 Randomized Clinical Trial. JAMA Oncol. 2020 MAY 21; . DOI: 10.1001/jamaoncol.2020.1024. 2020 May 21. PubMed PMID: 32437507; PMCID: PMC7243167.

Rogers LR (DT), Oppelt P, Nayak L (HICB). Hemolytic anemia associated with dapsone PCP prophylaxis in GBM patients with normal G6PD activity. Neuro-oncology. 2020 JUN 09; 22(6):892-893. DOI: 10.1093/neuonc/noaa026. PubMed PMID: 32047930; PMCID: PMC7283030.

Sandler KA, Cook RR, Ciezki JP (GU), Ross AE, Pomerantz MM, Nguyen PL, Shaikh T, Tran PT, Stock RG, Merrick GS, Demanes DJ, Spratt DE, Abu-Isa EI, Wedde TB, Lilleby W, Krauss DJ, Shaw GK, Alam R, Reddy CA, Song DY, Klein EA (GU), Stephenson AJ (GU), Tosoian JJ, Hegde JV, Yoo SM, et al. Prostate-only Versus Whole-pelvis Radiation with or Without a Brachytherapy Boost for Gleason Grade Group 5 Prostate Cancer: A Retrospective Analysis. Eur. Urol.. 2020 JAN 01; 77(1):3-10. DOI: 10.1016/j.eururo.2019.03.022. 2019 Apr 13. PubMed PMID: 30992160.

Sarn N, Jaini R (DT), Thacker S, Lee H, Dutta R, Eng C (CPC). Cytoplasmic-predominant Pten increases microglial activation and synaptic pruning in a murine model with autism-like phenotype. Mol. Psychiatry. 2020 FEB 13. DOI: 10.1038/s41380-020-0681-0. 2020 Feb 13. PubMed PMID: 32055008.

Saunders CN, Cornish AJ, Kinnersley B, Law PJ, Claus EB, Il'yasova D, Schildkraut J, Barnholtz-Sloan JS (CPC), Olson SH, Bernstein JL, Lai RK, Chanock S, Rajaraman P, Johansen C, Jenkins RB, Melin BS, Wrensch MR, Sanson M, Bondy ML, Houlston RS. Lack of association between modifiable exposures and glioma risk: a Mendelian randomization analysis. Neuro-oncology. 2020 FEB 20; 22(2):207-215. DOI: 10.1093/neuonc/noz209. PubMed PMID: 31665421.

Schöder H, Polley MY, Knopp MV, Hall NC, Kostakoglu L, Zhang J, Higley HR, Kelloff G, Liu H, Zelenetz A, Cheson BD, Wagner-Johnston ND, Kahl B, Friedberg JW, Hsi ED (HICB), Leonard JP, Schwartz LH, Wilson WH, Bartlett NL. Prognostic value of interim FDG-PET in diffuse large cell lymphoma: results from the CALGB 50303 Clinical Trial. Blood. 2020 JUN 18; 135(25):2224-2234. DOI: 10.1182/blood.2019003277. PubMed PMID: 32232481; PMCID: PMC7316220.

Schumacher F (CPC). Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan Nat Commun. 2020 MAR 24. PubMed PMID: ; PMCID: 32210231.

Sharifi N (GU). Deep androgen receptor suppression in prostate cancer exploits sexually dimorphic renal expression for systemic glucocorticoid exposure. Ann. Oncol.. 2020 MAR 31; . PubMed PMID: ; PMCID: 32057540.

Sharma A, Alswillah T, Kapoor I, Debjani P, Willard B (NPA), Summers MK, Gong Z (MO), Almasan A (MO). USP14 is a deubiquitinase for Ku70 and critical determinant of non-homologous end joining repair in autophagy and PTEN-deficient cells. Nucleic Acids Res.. 2020 JAN 24; 48(2):736-747. DOI: 10.1093/nar/gkz1103. PubMed PMID: 31740976; PMCID: PMC7145659.

Siddiqui MS, Van Natta ML, Connelly MA, Vuppalanchi R, Neuschwander-Tetri BA, Tonascia J, Guy C, Loomba R, Dasarathy S (MO), Wattacheril J, Chalasani N, Sanyal AJ. Impact of obeticholic acid on the lipoprotein profile in patients with non-alcoholic steatohepatitis. J. Hepatol.. 2020 JAN 01; 72(1):25-33. DOI: 10.1016/j.jhep.2019.10.006. 2019 Oct 18. PubMed PMID: 31634532; PMCID: PMC6920569.

Smith ZL, Elmunzer BJ, Cooper GS (CPC), Chak A (GICG). Real-World Practice Patterns in the Era of Rectal Indomethacin for Prophylaxis Against Post-ERCP Pancreatitis in a High-Risk Cohort. Am. J. Gastroenterol.. 2020 JUN 01; 115(6):934-940. DOI: 10.14309/ajg.0000000000000623. PubMed PMID: 32496740.

Stein EM, Fathi AT, DiNardo CD, Pollyea DA, Roboz GJ, Collins R, Sekeres MA (HICB), Stone RM, Attar EC, Frattini MG, Tosolini A, Xu Q, See WL, MacBeth KJ, de Botton S, Tallman MS, Kantarjian HM. Enasidenib in patients with mutant IDH2 myelodysplastic syndromes: a phase 1 subgroup analysis of the multicentre, AG221-C-001 trial. Lancet Haematol. 2020 APR 01; 7(4):e309-e319. DOI: 10.1016/S2352-3026(19)30284-4. 2020 Mar 5. PubMed PMID: 32145771.

Takeda R, Asada S, Park SJ, Yokoyama A, Becker HJ, Kanai A, Visconte V, Hershberger CE, Hayashi Y, Yonezawa T, Tamura M, Fukushima T, Tanaka Y, Fukuyama T, Matsumoto A, Yamasaki S, Nakai K, Yamazaki S, Inaba T, Shibata T, Inoue D, Honda H, Goyama S, Maciejewski JP (HICB), Kitamura T. HHEX promotes myeloid transformation in cooperation with mutant ASXL1. Blood. 2020 JUN 03; . DOI: 10.1182/blood.2019004613. 2020 Jun 3. PubMed PMID: 32492700.

Tao W, Chu C, Zhou W, Huang Z, Zhai K, Fang X, Huang Q, Zhang A, Wang X, Yu X, Huang H, Wu Q, Sloan AE (DT), Yu JS (MO), Li X (HICB), Stark GR (MO), Rich JN, Bao S (MO). Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma. Nat Commun. 2020 JUN 15; 11(1):3015. DOI: 10.1038/s41467-020-16827-z. 2020 Jun 15. PubMed PMID: 32541784; PMCID: PMC7295765.

Touat M, Li YY, Boynton AN, Spurr LF, Iorgulescu JB, Bohrson CL, Cortes-Ciriano I, Birzu C, Geduldig JE, Pelton K, Lim-Fat MJ, Pal S, Ferrer-Luna R, Ramkissoon SH, Dubois F, Bellamy C, Currimjee N, Bonardi J, Qian K, Ho P, Malinowski S, Taquet L, Jones RE, Shetty A, Chow KH, ...Barnholtz-Sloan JBS (CPC)... et al. Mechanisms and therapeutic implications of hypermutation in gliomas. Nature. 2020 APR 01; 580(7804):517-523. DOI: 10.1038/s41586-020-2209-9. 2020 Apr 15. PubMed PMID: 32322066.

Turaga SM, Silver DJ, Bayik D, Paouri E, Peng S, Lauko A, Alban TJ, Borjini N, Stanko S, Naik U, Keri RA (MO), Connor JR, Barnholtz-Sloan JS (CPC), Rubin JB, Berens M, Davalos D, Lathia JD (MO). JAM-A functions as a female microglial tumor suppressor in glioblastoma. Neuro-oncology. 2020 JUN 27; . DOI: 10.1093/neuonc/noaa148. 2020 Jun 27. PubMed PMID: 32592484.

Vander Velde R, Yoon N, Marusyk V, Durmaz A, Dhawan A, Miroshnychenko D, Lozano-Peral D, Desai B, Balynska O, Poleszhuk J, Kenian L, Teng M, Abazeed M, Mian O (GU), Tan AC, Haura E, Scott J (DT), Marusyk A. Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures. Nat Commun. 2020 MAY 14; 11(1):2393. DOI: 10.1038/s41467-020-16212-w. 2020 May 14. PubMed PMID: 32409712; PMCID: PMC7224215.

Vijayaraghavalu S, Gao Y, Rahman MT, Rozic R, Sharifi N (GU), Midura RJ, Labhasetwar V (CI). Synergistic combination treatment to break cross talk between cancer cells and bone cells to inhibit progression of bone metastasis. Biomaterials. 2020 JAN 01; 227:119558. DOI: 10.1016/j.biomaterials.2019.119558. 2019 Oct 18. PubMed PMID: 31654872; PMCID: PMC6870877.

Xie Y, Zhao Y, Shi L, Li W, Chen K, Li M, Chen X, Zhang H, Li T, Yu MI, Yao X, Shao D, Ke Z, Li J, Chen Y, Zhang X, Cui J, Cui S, Leng Q, Cadwell K, Li X (HICB), Wei H, Zhang H, Li H, Xiao H. Gut epithelial TSC1/mTOR controls RIPK3-dependent necroptosis in intestinal inflammation and cancer. J. Clin. Invest.. 2020 APR 01; 130(4):2111-2128. DOI: 10.1172/JCI133264. PubMed PMID: 31961824; PMCID: PMC7108921.

Yin J, Kim SS, Choi E, Oh YT, Lin W, Kim TH, Sa JK, Hong JH, Park SH, Kwon HJ, Jin X, You Y, Kim JH, Kim H, Son J, Lee J (MO), Nam DH, Choi KS, Shi B, Gwak HS, Yoo H, Iavarone A, Kim JH, Park JB. ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages. Nat Commun. 2020 JUN 12; 11(1):2978. DOI: 10.1038/s41467-020-16789-2. 2020 Jun 12. PubMed PMID: 32532977; PMCID: PMC7293269.

Zhan X, Guo S, Li Y, Ran H, Huang H, Mi L, Wu J, Wang X, Xiao D, Chen L, Li D, Zhang S, Yan X, Yu Y, Li T, Han Q, He K, Cui J, Li T, Zhou T, Rich JN, Bao S (MO), Zhang X, Li A, Man J. Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex-mediated STAT1 downregulation. J. Exp. Med.. 2020 MAY 04; 217(5). DOI: 10.1084/jem.20191340. PubMed PMID: 32181805; PMCID: PMC7201922.

Zhang A, Tao W, Zhai K, Fang X, Huang Z, Yu JS (MO), Sloan AE (DT, CI), Rich JN, Zhou W, Bao S (MO). Protein Sumoylation with SUMO1 Promoted by Pin1 in Glioma Stem Cells Augments Glioblastoma Malignancy. Neuro-oncology. 2020 JUN 27; . DOI: 10.1093/neuonc/noaa150. 2020 Jun 27. PubMed PMID: 32592588.

Zhang C, Ostrom QT, Hansen HM, Gonzalez-Maya J, Hu D, Ziv E, Morimoto L, de Smith AJ, Muskens IS, Kline CN, Vaksman Z, Hakonarson H, Diskin SJ, Kruchko C, Barnholtz-Sloan JS (CPC), Ramaswamy V, Ali-Osman F, Bondy ML, Taylor MD, Metayer C, Wiemels JL, Walsh KM. European genetic ancestry associated with risk of childhood ependymoma. Neuro-oncology. 2020 JUN 02; . DOI: 10.1093/neuonc/noaa130. 2020 Jun 2. PubMed PMID: 32607579.

Zhong J, Jermusyk A, Wu L, Hoskins JW, Collins I, Mocci E, Zhang M, Song L, Chung CC, Zhang T, Xiao W, Albanes D, Andreotti G, Arslan AA, Babic A, Bamlet WR, Beane-Freeman L, Berndt S, Borgida A, Bracci PM, Brais L, Brennan P, Bueno-de-Mesquita B, Buring J, Canzian F, ...Klein E (GU)... et al. A Transcriptome-Wide Association Study (TWAS) Identifies Novel Candidate Susceptibility Genes for Pancreatic Cancer. J. Natl. Cancer Inst.. 2020 JAN 09; . DOI: 10.1093/jnci/djz246. 2020 Jan 9. PubMed PMID: 31917448.