Opportunities for Pilot Projects from Cancer Innovation Award

The Case Comprehensive Cancer Center is providing seed funding for highly innovative and impactful proposals that will generate key data for larger, nationally competitive grants. Projects must be transformative in nature and may focus on technology development, innovative biological or therapeutic questions, novel concepts in catchment-based research, or topics that have the potential to overturn dogma. Investigators should submit novel ideas that are high risk and exceptionally innovative.

This RFA is open to all Case CCC Members. Proposals cannot be concurrently funded by other sources or by the Cancer Center.

Award Description

  • Each research project can request a budget of up to $75,000 for one year.

  • Research projects should be completed within one year.

  • Funds must be expended within the 12 month funding period, as cost extensions will not be granted.

Funding Criteria

  • Strong investigative teams of Case Comprehensive Cancer Center members.

  • Projects must be highly innovative and potentially transformative to be deemed responsive to this RFA.

  • All materials to complete the project (IRB, bio-samples, reagents, mice imaging data) should be in-hand or readily available. Collection of new patient cohorts as the primary focus of the work is not responsive to this RFA.

  • Projects must have a high likelihood of subsequent national-level funding.

  • While investigators can be collaborators on multiple applications, only one application will be accepted per lead PI. And PIs are allowed one award per year (i.e., no concurrent awards).

  • All funds for shared resources must involve Case CCC facilities unless the use of a shared resource(s) at another NCI-funded institution is sufficiently justified.


Letter of Intent due Friday, February 18, 2022. Submit LOIs by email to Bill Schiemann wps20@case.edu and casecccpilots@case.edu. Review detailed instructions before submitting LOI.

Full invited applications due Friday, March 18, 2022. Please submit all materials online via InfoReady.

View application instructions

Contact casecccpilots@case.edu with any questions.