GU Malignancies

Program Themes

  • Discover mechanisms of response and resistance in prostate and renal cancer
  • Develop novel biomarkers across GU malignancies
  • Ascertain the immunomodulatory environment and develop novel immunotherapeutic clinical trials 

Program Information

The overarching goal of the GU Malignancies Program is to explore fundamental biologic pathways of critical importance to the development and progression of prostate and renal cancer and to foster translational, investigator-initiated clinical trials to advance therapeutic options.

To provide additional structure and promote cohesion within the larger Program, investigators have been further organized around two scientific focus areas:

  • Prostate Cancer - includes genetic susceptibility and molecular basis, chemoprevention, molecular biomarkers of prognosis and therapeutic targeting of the IGF and PI3K/Akt/mTOR axis
  • Renal Cancer - includes molecular and clinical biomarkers of prognosis, response and resistance; immunomodulatory effects of treatment, and therapeutic targeting of angiogenesis and the PI3K/Akt/mTOR axis

Program Members

  • Portrait of Tatiana Byzova

    Tatiana V. Byzova, PhD

    Assistant Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: byzovat@ccf.org

    Phone: 216.445.4312

  • Portrait of Steven Campbell in white coat

    Steven C. Campbell, MD, PhD

    Professor
    Department of Surgery
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: campbes3@ccf.org

    Phone: 216.444.5595

  • Portrait of Abhishek Chakraborty

    Abhishek A. Chakraborty, PhD

    Assistant Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: chakraa@ccf.org

    Phone: 216.445.6620

  • Jay P. Ciezki, MD

    Professor
    Department of Medicine
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: ciezkij@ccf.org

    Phone: 216.445.9465

  • Portrait of Jennifer Cullen

    Jennifer Cullen, PhD, MPH

    James T. Pardee – Carl A. Gerstacker Professorship in Cancer Research
    School of Medicine
    Associate Professor
    Department of Population and Quantitative Health Sciences
    School of Medicine
    Associate Director for Cancer Population Sciences
    Case Comprehensive Cancer Center

    Email: jxc1650@case.edu

    Phone: 216.368.1965

  • David Danielpour
    David Schwartz Photography

    David Danielpour, PhD

    Professor
    Case Comprehensive Cancer Center
    Associate Professor
    Department of Urology
    School of Medicine
    Associate Professor
    Department of Pharmacology
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: dxd49@case.edu

    Phone: 216.368.5670

  • Claudia M. Diaz-Montero, PhD

    Adjunct Assistant Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: diazc@ccf.org

  • Portrait of Joseph DiDonato

    Joseph A. DiDonato, PhD

    Assistant Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: didonaj@ccf.org

    Phone: 216.444.8178

  • James H. Finke, PhD

    Professor
    Department of Molecular Medicine
    School of Medicine
    Professor
    Department of Pathology
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: finkej@ccf.org

    Phone: 216.444.5186

  • Jorge A. Garcia, MD

    Assistant Professor
    Department of Medicine
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: Jorge.Garcia@UHhospitals.org

  • Portrait of Timothy Gilligan

    Timothy D. Gilligan, MD

    Associate Professor
    Department of Medicine
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: gilligt@ccf.org

    Phone: 216.444.0391

  • Magdalena M. Grabowska, PhD

    Assistant Professor
    Department of Urology
    School of Medicine
    Assistant Professor
    Department of Biochemistry
    School of Medicine
    Assistant Professor
    Department of Pharmacology
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: mmg126@case.edu

    Phone: 216.368.5736

  • Portrait of Shilpa Gupta

    Shilpa Gupta, MD

    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: guptas5@ccf.org

  • Image of headshot of Ann Harris

    Ann Harris, PhD

    Vice Chair of Research
    Department of Genetics and Genome Sciences
    School of Medicine
    Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: ann.harris@case.edu

    Phone: 216.368.6651

  • Hannelore Heemers, PhD

    Adjunct Assistant Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: heemerh@ccf.org

    Phone: 216.445.7357

  • Portrait of Warren DW Heston

    Warren D.W. Heston, PhD

    Adjunct Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: hestonw@ccf.org

    Phone: 216.444.8181

  • Portrait of Tae Hyun Hwang

    Tae Hyun Hwang, PhD

    Assistant Professor
    Molecular Medicine
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: hwangt@ccf.org

    Phone: 216.442.5565

  • Eric A. Klein, MD

    Professor
    Department of Surgery
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: kleine@ccf.org

    Phone: 216.444.5601

  • Byron Lee, MD, PhD

    Assistant Professor
    Department of Surgery
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: leeb4@ccf.org

  • Dr. Gregory MacLennan

    Gregory T. MacLennan, MD

    Professor
    Department of Pathology
    School of Medicine
    Professor
    Department of Urology
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: gregory.maclennan@UHhospitals.org

    Phone: 216.844.7452

  • Prateek Mendiratta, MD

    Prateek Mendiratta, MD

    Assistant Professor
    Department of Medicine
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: prateek.mendiratta@UHhospitals.org

  • Portrait of Omar Mian

    Omar Y. Mian , MD, PhD

    Assistant Professor
    Department of Medicine
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: miano@ccf.org

    Phone: 216.445.3273

  • Portrait of Carvell Nguyen

    Carvell T. Nguyen, MD, PhD

    Assistant Professor
    Department of Surgery
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: cnguyen4@metrohealth.org

    Phone: 216.778.7968

  • Portrait of Lee Ponsky

    Lee E. Ponsky, MD

    Professor
    Department of Urology
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: lee.ponsky@UHhospitals.org

    Phone: 216.844.4831

  • Larisa Schwartzman, MD

    Assistant Professor
    Department of Medicine
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: schwarl@ccf.org

  • Portrait of Nima Sharifi

    Nima Sharifi, MD

    Professor
    Department of Molecular Medicine
    School of Medicine
    Co-Leader
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: sharifn@ccf.org

    Phone: 216.445.9750

  • Portrait of Jonathan Shoag, MD

    Jonathan Shoag, MD

    Assistant Professor
    Department of Urology
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: jxs218@case.edu

  • Robert H. Silverman

    Robert H. Silverman , PhD

    Professor
    Department of Molecular Medicine
    School of Medicine
    Professor
    Department of Biochemistry
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: silverr@ccf.org

    Phone: 216.445.9650

  • Portrait of Jonathan Smith

    Jonathan D. Smith , PhD

    Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: smithj4@ccf.org

    Phone: 216.444.2248

  • Portrait of George Stark

    George R. Stark , PhD

    Member
    Molecular Oncology Program
    Case Comprehensive Cancer Center
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: starkg@ccf.org

    Phone: 216.444.6062

  • Image of headshot of Giuseppe Strangi

    Giuseppe Strangi , PhD

    Professor and Ohio Research Scholar in Surfaces of Advanced Materials
    Department of Physics
    College of Arts and Sciences
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: gxs284@case.edu

    Phone: 216.368.6918

  • Portrait of Angela Ting

    Angela H. Ting, PhD

    Associate Professor
    Department of Molecular Medicine
    School of Medicine
    Assistant Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: tinga@ccf.org

    Phone: 216.444.0682

  • Portrait of Oliver Wessely

    Oliver Wessely, PhD

    Associate Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: wesselo@ccf.org

    Phone: 216.444.3050

  • Portrait of Hui Zhu

    Hui Zhu, MD

    Assistant Professor
    Department of Surgery
    School of Medicine
    Member
    GU Malignancies Program
    Case Comprehensive Cancer Center

    Email: zhuh@ccf.org

    Phone: 216.444.5600