GU Malignancies

Program Themes

  • Discover mechanisms of response and resistance in prostate and renal cancer
  • Develop novel biomarkers across GU malignancies
  • Ascertain the immunomodulatory environment and develop novel immunotherapeutic clinical trials 

Program Information

The overarching goal of the GU Malignancies Program is to explore fundamental biologic pathways of critical importance to the development and progression of prostate and renal cancer and to foster translational, investigator-initiated clinical trials to advance therapeutic options.

To provide additional structure and promote cohesion within the larger Program, investigators have been further organized around two scientific focus areas:

  • Prostate Cancer - includes genetic susceptibility and molecular basis, chemoprevention, molecular biomarkers of prognosis and therapeutic targeting of the IGF and PI3K/Akt/mTOR axis
  • Renal Cancer - includes molecular and clinical biomarkers of prognosis, response and resistance; immunomodulatory effects of treatment, and therapeutic targeting of angiogenesis and the PI3K/Akt/mTOR axis

Program Members

Tatiana V. Byzova, PhD
Assistant Professor, Molecular Cardiology

Steven C. Campbell, MD, PhD
Professor, Urology

Abhishek Chakraborty, MD
Assistant Professor, Cancer Biology

Jay P. Ciezki, MD
Associate Professor, Radiation Oncology

David Danielpour, PhD
Professor, General Medical Sciences (Oncology)

Claudia M. Diaz-Montero, PhD
Assistant Professor, Immunology

Joseph A. DiDonato, PhD
Assistant Professor, Cellular and Molecular Medicine

James H. Finke, PhD
Professor, Immunology

Jorge A. Garcia, MD
Assistant Professor, Solid Tumor Oncology

Timothy D. Gilligan, MD
Associate Professor, Solid Tumor Oncology

Magdalena M. Grabowska, PhD
Assistant Professor, Urology

Shilpa Gupta, MD
Staff, Solid Tumor Oncology

Ann Harris, PhD
Professor, Genetics and Genome Sciences

Hannelore Heemers, PhD
Associate Staff, Cancer Biology

Warren D.W. Heston, PhD
Professor, Cancer Biology

Christopher J. Hoimes, DO
Assistant Professor, Hematology and Oncology 

Tae Hyung Hwang, PhD
Assistant Professor, Quantitative Health Sciences

Eric A. Klein, MD
Professor, Urology

Byron Lee, MD, PhD
Associate Staff, Urology

Gregory T. MacLennan, MD
Professor, Pathology

Prateek Mendiratta, MD
Assistant Professor, Hematology and Oncology

Omar Y. Mian, MD, PhD
Assistant Professor, Translational Hematology and Oncology Research

Carvell Nguyen, MD, PhD
Assistant Professor, Surgery-Urology

Lee E. Ponsky, MD
Professor, Urology

Larisa Schwartzman, MD
Assistant Professor, Hematology and Oncology

Nima Sharifi, MD
Leader, GU Malignancies Program
Associate Professor, Cancer Biology

Sanjeev Shukla, PhD
Instructor, Urology

Robert H. Silverman, PhD
Professor, Cancer Biology

Jonathan D. Smith, PhD
Professor, Cellular and Molecular Medicine

George R. Stark, PhD
Professor, Molecular Genetics

Andrew J. Stephenson, MD
Associate Professor, Urology

Giuseppe Strangi, PhD
Professor, Physics

Angela Ting, MD
Associate Professor, Genomic Medicine Institute

Oliver Wessely, PhD
Associate Professor, Cellular and Molecular Medicine

Hui Zhu, MD
Assistant Professor, Urology