Program Themes
- Discover mechanisms of response and resistance in prostate and renal cancer
- Develop novel biomarkers across GU malignancies
- Ascertain the immunomodulatory environment and develop novel immunotherapeutic clinical trials
Program Information
The overarching goal of the GU Malignancies Program is to explore fundamental biologic pathways of critical importance to the development and progression of prostate and renal cancer and to foster translational, investigator-initiated clinical trials to advance therapeutic options.
To provide additional structure and promote cohesion within the larger Program, investigators have been further organized around two scientific focus areas:
- Prostate Cancer - includes genetic susceptibility and molecular basis, chemoprevention, molecular biomarkers of prognosis and therapeutic targeting of the IGF and PI3K/Akt/mTOR axis
- Renal Cancer - includes molecular and clinical biomarkers of prognosis, response and resistance; immunomodulatory effects of treatment, and therapeutic targeting of angiogenesis and the PI3K/Akt/mTOR axis
Program Members
Tatiana V. Byzova, PhD
Assistant ProfessorDepartment of Molecular MedicineSchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: byzovat@ccf.org
Phone: 216.445.4312
Steven C. Campbell, MD, PhD
ProfessorDepartment of SurgerySchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: campbes3@ccf.org
Phone: 216.444.5595
Abhishek A. Chakraborty, PhD
Assistant ProfessorDepartment of Molecular MedicineSchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: chakraa@ccf.org
Phone: 216.445.6620
Jay P. Ciezki, MD
ProfessorDepartment of MedicineSchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: ciezkij@ccf.org
Phone: 216.445.9465
Jennifer Cullen, PhD, MPH
James T. Pardee – Carl A. Gerstacker Professorship in Cancer ResearchSchool of MedicineAssociate ProfessorDepartment of Population and Quantitative Health SciencesSchool of MedicineAssociate Director for Cancer Population SciencesCase Comprehensive Cancer CenterEmail: jxc1650@case.edu
Phone: 216.368.1965
- David Schwartz Photography
David Danielpour, PhD
ProfessorCase Comprehensive Cancer CenterAssociate ProfessorDepartment of UrologySchool of MedicineAssociate ProfessorDepartment of PharmacologySchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: dxd49@case.edu
Phone: 216.368.5670
Claudia M. Diaz-Montero, PhD
Adjunct Assistant ProfessorDepartment of Molecular MedicineSchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: diazc@ccf.org
Joseph A. DiDonato, PhD
Assistant ProfessorDepartment of Molecular MedicineSchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: didonaj@ccf.org
Phone: 216.444.8178
James H. Finke, PhD
ProfessorDepartment of Molecular MedicineSchool of MedicineProfessorDepartment of PathologySchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: finkej@ccf.org
Phone: 216.444.5186
Jorge A. Garcia, MD
Assistant ProfessorDepartment of MedicineSchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: Jorge.Garcia@UHhospitals.org
Timothy D. Gilligan, MD
Associate ProfessorDepartment of MedicineSchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: gilligt@ccf.org
Phone: 216.444.0391
Magdalena M. Grabowska, PhD
Assistant ProfessorDepartment of UrologySchool of MedicineAssistant ProfessorDepartment of BiochemistrySchool of MedicineAssistant ProfessorDepartment of PharmacologySchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: mmg126@case.edu
Phone: 216.368.5736
Shilpa Gupta, MD
MemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: guptas5@ccf.org
Ann Harris, PhD
Vice Chair of ResearchDepartment of Genetics and Genome SciencesSchool of MedicineProfessorDepartment of Genetics and Genome SciencesSchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: ann.harris@case.edu
Phone: 216.368.6651
Hannelore Heemers, PhD
Adjunct Assistant ProfessorDepartment of Molecular MedicineSchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: heemerh@ccf.org
Phone: 216.445.7357
Warren D.W. Heston, PhD
Adjunct ProfessorDepartment of Molecular MedicineSchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: hestonw@ccf.org
Phone: 216.444.8181
Tae Hyun Hwang, PhD
Assistant ProfessorMolecular MedicineSchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: hwangt@ccf.org
Phone: 216.442.5565
Eric A. Klein, MD
ProfessorDepartment of SurgerySchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: kleine@ccf.org
Phone: 216.444.5601
Byron Lee, MD, PhD
Assistant ProfessorDepartment of SurgerySchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: leeb4@ccf.org
Gregory T. MacLennan, MD
ProfessorDepartment of PathologySchool of MedicineProfessorDepartment of UrologySchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: gregory.maclennan@UHhospitals.org
Phone: 216.844.7452
Prateek Mendiratta, MD
Assistant ProfessorDepartment of MedicineSchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterOmar Y. Mian , MD, PhD
Assistant ProfessorDepartment of MedicineSchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: miano@ccf.org
Phone: 216.445.3273
Carvell T. Nguyen, MD, PhD
Assistant ProfessorDepartment of SurgerySchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: cnguyen4@metrohealth.org
Phone: 216.778.7968
Lee E. Ponsky, MD
ProfessorDepartment of UrologySchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: lee.ponsky@UHhospitals.org
Phone: 216.844.4831
Larisa Schwartzman, MD
Assistant ProfessorDepartment of MedicineSchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: schwarl@ccf.org
Nima Sharifi, MD
ProfessorDepartment of Molecular MedicineSchool of MedicineCo-LeaderGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: sharifn@ccf.org
Phone: 216.445.9750
Jonathan Shoag, MD
Assistant ProfessorDepartment of UrologySchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: jxs218@case.edu
Robert H. Silverman , PhD
ProfessorDepartment of Molecular MedicineSchool of MedicineProfessorDepartment of BiochemistrySchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: silverr@ccf.org
Phone: 216.445.9650
Jonathan D. Smith , PhD
ProfessorDepartment of Molecular MedicineSchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: smithj4@ccf.org
Phone: 216.444.2248
George R. Stark , PhD
MemberMolecular Oncology ProgramCase Comprehensive Cancer CenterMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: starkg@ccf.org
Phone: 216.444.6062
Giuseppe Strangi , PhD
Professor and Ohio Research Scholar in Surfaces of Advanced MaterialsDepartment of PhysicsCollege of Arts and SciencesMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: gxs284@case.edu
Phone: 216.368.6918
Angela H. Ting, PhD
Associate ProfessorDepartment of Molecular MedicineSchool of MedicineAssistant ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: tinga@ccf.org
Phone: 216.444.0682
Oliver Wessely, PhD
Associate ProfessorDepartment of Molecular MedicineSchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: wesselo@ccf.org
Phone: 216.444.3050
Hui Zhu, MD
Assistant ProfessorDepartment of SurgerySchool of MedicineMemberGU Malignancies ProgramCase Comprehensive Cancer CenterEmail: zhuh@ccf.org
Phone: 216.444.5600