Program Themes
- Discover mechanisms of response and resistance in prostate and renal cancer
- Develop novel biomarkers across GU malignancies
- Ascertain the immunomodulatory environment and develop novel immunotherapeutic clinical trials
Program Information
The overarching goal of the GU Malignancies Program is to explore fundamental biologic pathways of critical importance to the development and progression of prostate and renal cancer and to foster translational, investigator-initiated clinical trials to advance therapeutic options.
To provide additional structure and promote cohesion within the larger Program, investigators have been further organized around two scientific focus areas:
- Prostate Cancer - includes genetic susceptibility and molecular basis, chemoprevention, molecular biomarkers of prognosis and therapeutic targeting of the IGF and PI3K/Akt/mTOR axis
- Renal Cancer - includes molecular and clinical biomarkers of prognosis, response and resistance; immunomodulatory effects of treatment, and therapeutic targeting of angiogenesis and the PI3K/Akt/mTOR axis
Program Members
Tatiana V. Byzova, PhD
Assistant Professor, Molecular Cardiology
byzovat@ccf.org
Steven C. Campbell, MD, PhD
Professor, Urology
campbes3@ccf.org
Abhishek Chakraborty, MD
Assistant Professor, Cancer Biology
chakraa@ccf.org
Jay P. Ciezki, MD
Associate Professor, Radiation Oncology
ciezkij@ccf.org
David Danielpour, PhD
Professor, General Medical Sciences (Oncology)
dxd49@case.edu
Claudia M. Diaz-Montero, PhD
Assistant Professor, Immunology
diazc2@ccf.org
Joseph A. DiDonato, PhD
Assistant Professor, Cellular and Molecular Medicine
didonaj@ccf.org
James H. Finke, PhD
Professor, Immunology
finkej@ccf.org
Jorge A. Garcia, MD
Assistant Professor, Solid Tumor Oncology
garciaj4@ccf.org
Timothy D. Gilligan, MD
Associate Professor, Solid Tumor Oncology
gilligt@ccf.org
Magdalena M. Grabowska, PhD
Assistant Professor, Urology
mmg126@case.edu
Shilpa Gupta, MD
Staff, Solid Tumor Oncology
guptas5@ccf.org
Ann Harris, PhD
Professor, Genetics and Genome Sciences
ann.harris@case.edu
Hannelore Heemers, PhD
Associate Staff, Cancer Biology
heemerh@ccf.org
Warren D.W. Heston, PhD
Professor, Cancer Biology
hestonw@ccf.org
Christopher J. Hoimes, DO
Assistant Professor, Hematology and Oncology
christopher.hoimes@case.edu
Tae Hyung Hwang, PhD
Assistant Professor, Quantitative Health Sciences
hwangt@ccf.org
Eric A. Klein, MD
Professor, Urology
kleine@ccf.org
Byron Lee, MD, PhD
Associate Staff, Urology
leeb4@ccf.org
Gregory T. MacLennan, MD
Professor, Pathology
gregory.maclennan@UHhospitals.org
Prateek Mendiratta, MD
Assistant Professor, Hematology and Oncology
prateek.mendiratta@UHhospitals.org
Omar Y. Mian, MD, PhD
Assistant Professor, Translational Hematology and Oncology Research
miano@ccf.org
Carvell Nguyen, MD, PhD
Assistant Professor, Surgery-Urology
cnguyen4@metrohealth.org
Lee E. Ponsky, MD
Professor, Urology
lee.ponsky@UHhospitals.org
Larisa Schwartzman, MD
Assistant Professor, Hematology and Oncology
schwarl@ccf.org
Nima Sharifi, MD
Leader, GU Malignancies Program
Associate Professor, Cancer Biology
sharifn@ccf.org
Sanjeev Shukla, PhD
Instructor, Urology
sanjeev.shukla@case.edu
Robert H. Silverman, PhD
Professor, Cancer Biology
silverr@ccf.org
Jonathan D. Smith, PhD
Professor, Cellular and Molecular Medicine
smithj4@ccf.org
George R. Stark, PhD
Professor, Molecular Genetics
starkg@ccf.org
Andrew J. Stephenson, MD
Associate Professor, Urology
stephea2@ccf.org
Giuseppe Strangi, PhD
Professor, Physics
gxs284@case.edu
Angela Ting, MD
Associate Professor, Genomic Medicine Institute
tinga@ccf.org
Oliver Wessely, PhD
Associate Professor, Cellular and Molecular Medicine
wesselo@ccf.org
Hui Zhu, MD
Assistant Professor, Urology
zhuh@ccf.org