Craniopharyngioma - Case 1

A 47 year-old woman developed headaches and blurred vision. On examination, she had pallor of the optic discs and a bitemporal hemianopsia.


Note the Compression into the Sphenoid Sinus     Show the Tumor     Show the Gadolinium Enhancement

Craniopharyngioma. (Left) T1-weighted sagittal MRI; (Right) T1-weighted with gadolinium sagittal MRI. Note the presence of a large suprasellar mass that enhances and is partially cystic. Surgical removal demonstrated a craniopharyngioma.

Craniopharyngiomas arise in the suprasellar region and are often calcified and cystic. They are slow growing tumors that occur in children and adults, and can become very large in size. In children, they are thought to occur as a result of impaired embryogenesis of structures in or near the infundibulum of the pituitary gland. In adults, they are believed to occur as a result of metaplasia of pituitary squamous epithelium. Similar to pituitary macroadenomas, they may present with endocrine dysfunction or focal neurological signs due to mass effect in the suprasellar region.


Revised 11/28/06.
Copyrighted 2006. David C Preston