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A 44 year-old woman developed amenorrhea and headaches. Her examination was normal. |
Pituitary Microadenoma. T1-weighted with gadolinium sagittal MRI scan. Note the mass
that enhances and fills the sella. This lesion measured 6 mm and is a pituitary microadenoma.
By definition, pituitary microadenomas are benign tumors of the
pituitary gland that measure less than 10 mm in diameter. They
generally come to medical attention due to signs and symptoms of
endocrine dysfunction from excessive hormonal production, though some may be
non-secretory, and thus, clinically silent. The most commonly secreted hormone is prolactin,
resulting in galactorrhea, amenorrhea, infertility and loss of
libido. Less commonly secreted hormones may include ACTH (resulting
in Cushing's disease), growth hormone (resulting in acromegaly), TSH (resulting in hyperthryoidism), and the gonadotropins (resulting in sexual dysfunction and infertility). |
Revised
11/29/06.
Copyrighted 2006. David C Preston