Karla Coburn, PhD

Instructor
Department of Anatomy
School of Medicine

Teaching Information

Teaching Interests

Histology, Oral Histology, Embryology

Courses Taught

ANAT 412 Histology and Ultrastructure
HWDP 142 GI System in Health & Disease
HEWB 123 Facial Growth

Awards and Honors

Honored Professor – Biomedicine Degree
2020
Federal University of State of Rio de Janeiro (UNIRIO)
Honored Professor (Patron) – Biomedicine Degree
2019
Federal University of State of Rio de Janeiro (UNIRIO)
Honored Professor – Biomedicine Degree
2018
Federal University of State of Rio de Janeiro (UNIRIO)
Honored Professor (Patron) – Dental Course
2015
Federal University of Espirito Santo (UFES)
Honored Professor – Dental Course
2014
Federal University of Espirito Santo (UFES)
Best Poster Award
2014
Brazilian Society of Oncological Surgery of Espírito Santo
Second Place Poster Award
2014
Brazilian Society of Oncological Surgery of Espírito Santo
First Place in Scientific Forum
2014
38th Annual Dentistry Meeting at the Federal University of Espirito Santo (JUNCO)
Third Place Poster Award
2014
38th Annual Dentistry Meeting at the Federal University of Espirito Santo (JUNCO)
Honorable Mention Poster Award
2013
Experimental Biology Society Federation (FeSBE)
Meeting for the Brazilian Society of Cell Biology Honorable Mention
2008
Experimental Biology Society Federation (FeSBE)
Best Scientific Poster Award
2006
9th Meeting for the UNESCO Chair of Developmental Biology

External Appointments

Adjunct Professor – Anatomy and Physiology
Lone Star College – University Park, Texas
2019
2020
Associate Professor - Morphological Sciences Department- Biomedical Sciences Institute (ICB)
Federal University of State of Rio de Janeiro (UNIRIO), Rio De Janeiro, Brazil
2015
2018
Associate Professor – Morphology Department – Health Sciences Center
Federal University of Espirito Santo (UFES)
2009
2015
Adjunct Professor – Morphology Department – Health Sciences Center (CCS)
Federal University of Espirito Santo (UFES)
2004
2015

Publications

Publication Date

Lima-Pansini L.F., Lima N.S.C., Guss N.O., Alves I.S.S., Gama-de-Souza L.N., Graceli J.B, Pacheco M.S., Coburn K.L.A. Analysis of estrogen effects on eruption of rat molars. Accepted for publication at International Journal of Odontostomatology, volume 13, Issue 4, 2019.

Sandoval N., Lima N., Bautz W., Gama-De-Souza L., Coburn K. 2018: Matrix Metalloproteinase 2: A Possible Role in Tooth Development and Eruption. ODOVTOS - Int. J. Dental Sc. 2019; 21 (1): 41-51.

Lima NS, Magalhães IR, Lima-Pansini LF, Gama-de-Souza LN, Pacheco MS, Coburn KL. Bone Cells and Mast Cells Express MMP-9 During Tooth Eruption In Vivo. J Orofac Sci 2018;10:127-33.

Lorenzoni DC, Pinheiro LP, Nascimento HS, Menegardo CS, Silva RG, Bautz WG, Henriques JF, Almeida-Coburn KL, da Gama-de-Souza, LN. Could formaldehyde induce mutagenic and cytotoxic effects in buccal epithelial cells during anatomy classes? Med Oral Patol Oral Cir Bucal. 2017;22(1): e58–e63. DOI: 10.4317/medoral.21492.

De Angeli L, Marques LC, Reid-Silva EM, Silva Pacheco M, Almeida Coburn KL, Bautz WG, Barros LA, Gama-de-Souza LN. Expressão da laminina 332 em vasos de carcinomas de células escamosas orais [Expression of laminin 332 in oral squamous cell carcinoma vessels]. Revista Brasileira de Odontologia [Brazilian Journal of Dentistry]. 2016;73(3): 198. DOI: 10.18363/rbo.v73n3.p.198.

Alves ISS, Coser PHP, Loureiro GJZ, da Gama LPN, Ribeiro FDSS, Bautz WG, Coburn KLA, da Silva Pacheco M, de Souza LNDG. Fibrosis and Mast Cells in Colorectal Lesions: Significance in Adenoma-Colorectal Cancer Sequence and Association with Diet. J Gastrointest Cancer. 2016;47(3):278-86. DOI:10.1007/s12029-016-9829-1.

Paiva SN, Braga CC, Almeida-Coburn KL, Bautz WG, de Barros LAP, da Gama-de-Souza LN. Oral lichen planus: clinical profile and determination of oral epithelial dysplasia. Int. J. Odontostomat. 2016;10(1):99-106. DOI: 10.4067/s0718-381x2016000100016.

Cavalcante WS, Hsieh R, Lourenço SV, De Souza LNG, Almeida-Coburn KL, Barros LAP. Neural and Vascular Invasions of Oral Squamous Cell Carcinomas. J Oral Hyg Health. 2015;3(5):1-8. DOI: 10.4172/2332-0702.1000187.

Reis AH*, Almeida-Coburn KL*, Louza MP*, Cerqueira DM, Aguiar DP, Silva-Cardoso L, Mendes FA, Andrade LR, Einicker-Lamas M, Atella GC, Brito JM, Abreu JG. Plasma membrane cholesterol depletion disrupts prechordal plate and affects early forebrain patterning. Dev Biol. 2012;365(2):350-62. DOI: 10.1016/j.ydbio.2012.03.003.
* indicates equal contributions

Zhang X, Abreu JG, Yokota C, MacDonald BT, Singh S, Coburn KLA, Cheong SM, Zhang MM, Ye QZ, Hang HC, Steen H, He X. Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation. Cell. 2012;149(7):1565-77. DOI: 10.1016/j.cell.2012.04.039.

Barros LAP, Gama De Souza LN, Lourenço Carlos Maia RM; Grão-Velloso TR, Baltz W, Almeida-Coburn KL, Santos Nery T. Analysis of the dysplastic character of precancerous lesions, lichen planus, papillomas, inflammatory fibrous hyperplasia and squamous cell carcinoma: clinicopathological profile. Med Oral Patol Oral Cir Bucal. 2010;1: 20-21.

Castillo HA, Cravo RM, Azambuja AP, Simões-Costa MS, Sura-Trueba S, Gonzalez J, Slonimsky E, Almeida K, Abreu JG, de Almeida MA, et al. Insights into the organization of dorsal spinal cord pathways from an evolutionarily conserved raldh2 intronic enhancer. Development. 2010;137(3), 507-18. DOI: 10.1242/dev.043257.

Zeng X, Huang H, Tamai K, Zhang X, Harada Y, Yokota C, Almeida K, Wang J, Doble B, Woodgett J, et al. Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, disheveled and axin functions. Development. 2008;135(2):367-75. DOI: 10.1242/dev.013540.

Abreu JG, Almeida KL. Reprogramação Celular: novas alternativas para terapia com células-tronco. [Cell Reprogramming: New Alternatives to Stem Cell Therapy]. Ciência Hoje [Science Today]. 2006;38(225):26-31.

Book Chapter:
Almeida KL, Abreu J, Yan CYI. Neural Induction. In: Ulrich H, editor. Perspectives of Stem Cells: From tools for studying mechanisms of neuronal differentiation towards therapy. Springer Netherlands; 2010. p. 1-10.

Education

Post Doc
Developmental Biology, Molecular Biology, Histology
Federal University of Rio de Janeiro
2009
PhD
Morphological Sciences
Federal University of Rio de Janeiro
2008
Master of Science
Morphological Sciences
Federal University of Rio de Janeiro
2006
Doctor of Dental Surgery
Federal University of Espirito Santo
2002