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The Center for Genetic Research Ethics and Law (CGREAL) at Case Western Reserve University (CWRU) was established in 2004 with two missions: to conduct transdisciplinary research on ethical and policy issues in the design and conduct of human genetic research, and to recruit new scholars and trainees to work on these issues.

To date, CGREAL has explored a range of ethical issues in the design and conduct of genetic family studies, genetic epidemiology, and genomic variation research. In the next five years, we will follow the trajectory of genomics into its “translational” phase, where expanded research needs and higher clinical aspirations are creating new ethical, legal, and social challenges for genomic researchers and society.