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Emina Huang, MD
ProfessorDepartment of SurgerySchool of MedicineEmail: huange2@ccf.org
Phone: 216.442.5097
My lab investigates interactions of intestinal epithelia and the surrounding microenvironment in promoting progression to cancer; colitis-derived tumor initiating cells, induced pluripotent stem cells.
Sudha K. Iyengar, PhD
Professor and Vice Chair for ResearchDepartment of Population and Quantitative Health SciencesSchool of MedicineProfessorDepartment of Genetics and Genome SciencesSchool of MedicineProfessorDepartment of Ophthalmology and Visual SciencesSchool of MedicineMemberCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterEmail: sudha.iyengar@case.edu
Phone: 216.368.4388
I research molecular and statistical genetic dissection of multifactorial diseases; common chronic diseases of the eye and the kidney; speech sound disorder.
Mark Jackson, PhD
ProfessorDepartment of PathologySchool of MedicineAssociate Director for Training and EducationCase Comprehensive Cancer CenterDirector, Cancer Biology Training ProgramMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: mark.w.jackson@case.edu
Phone: 216.368.1276
My area of investigation includes tumor microenvironment, tumor immunology, mestastasis, and cellular transformation.
Beata Jastrzebska, PhD
Assistant ProfessorDepartment of PharmacologySchool of MedicineMemberCleveland Center for Membrane & Structural BiologyEmail: bxj27@case.edu
Phone: 216.368.5683
My areas of research include signaling complexes of rhodopsin, rhodopsin oligomeric organization in signal transduction, Molecular bases of light-induced retinal degeneration, and mouse models of retinal degenerative diseases.
Fulai Jin, PhD
Associate ProfessorDepartment of Genetics and Genome SciencesSchool of MedicineAssociate ProfessorDepartment of Computer and Data SciencesCase School of EngineeringCo-LeaderCancer Genomics and Epigenomics ProgramCase Comprehensive Cancer CenterAssociate ProfessorDepartment of Population and Quantitative Health SciencesSchool of MedicineEmail: fulai.jin@case.edu
Phone: 216.368.1811
I study molecular mechanisms and gene regulatory functions of 3D genome architecture, computational and system biology tools for integrative analysis of genomic data, and single cell transcriptome/epigenome technologies in health and disease.
Ge Jin, PhD
MemberPopulation and Cancer Prevention ProgramCase Comprehensive Cancer CenterEmail: ge.jin@case.edu
Phone: 216.368.3791
We are investigating the effect of exosomes, a group of extracellular vesicles (EVs), from virus infected cells on cancer progression, inflammation and co-infection. We are utilizing the "EV-omics", including proteomics, RNAseq, lipidomics and metabolics to identify exosomes cargoes that contribute to diseases. We are also developing exosome therapeutic techniques in cancer treatment and regenerative medicine.
David Kang, PhD
ProfessorDepartment of PathologySchool of MedicineHoward T. Karsner Professor in PathologyEmail: dek94@case.edu
Phone: 216.368.0488
Dr. Kang’s research focuses on the molecular pathways underlying aberrant proteinopathy and neurotoxicity in Alzheimer’s disease (AD) and Related Dementias (ADRDs), including Frontotemporal dementia (FTD)-Amyotrophic lateral sclerosis (ALS) spectrum disorders and Lewy body disorders (LBD).
Hung-Ying Kao, PhD
ProfessorDepartment of BiochemistrySchool of MedicineDirector of Graduate ProgramsDepartment of BiochemistrySchool of MedicineMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: hung.kao@case.edu
Phone: 216.368.1150
Our lab is interested in the underlying mechanism and identifying anticancer targets of breast cancer.
Mihriban Karaayvaz, PhD
Assistant ProfessorCleveland Clinic Lerner College of MedicineLerner Research Institute, Cleveland ClinicSchool of MedicineMemberMolecular Oncology ProgramCase Comprehensive Cancer CenterEmail: karaaym@ccf.org
The Karaayvaz Lab’s main research focus is to understand the early events in breast cancer development in high-risk patients. We employ state-of-the-art single cell and imaging approaches to dissect molecular heterogeneity in pre-malignant and malignant lesions of the breast. Our goal is to leverage the knowledge gained from these studies and develop innovative strategies for breast cancer chemoprevention and treatment.
Gunnur Karakurt, PhD
Associate ProfessorSchool of MedicineEmail: gkk6@case.edu
Intimate partner violence is a complex problem that intersects issues from the biological level to larger societal issues intersecting individuals and families. We are interested in preventing and treating Intimate Partner Violence. Our lab aims to develop a decision-making model to improve treatment outcomes by identifying subgroups of the population who respond similarly to IPV treatments and identify which IPV treatments work best for each subgroup based on violence typology, population characteristics, and treatment options. We are also interested in understanding the interactions in which violent behaviors emerge and escalate, and how this is related to mental and physical health.