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Chris A. Flask, PhD

Associate Professor of Radiology, Secondary Appointments: Biomedical Engineering, and Pediatrics; Scientific Director, Case Center for Imaging Research 216.844.4963 (o)

Case Western Reserve University
Bolwell Bldg, Rm. B115
11100 Euclid Ave.
Cleveland, OH 44106


Research Interests

  • Quantitative Magnetic Resonance Imaging
  • MRI Physics and Pulse Sequence Design
  • Lung imaging: cystic fibrosis
  • Kidney imaging: polycystic kidney disease, sickle cell disease, diabetic nephropathy
  • Liver imaging: inflammation and fibrosis

  • PhD Biomedical Engineering, Case Western Reserve University, 2005
  • MS Chemical Engineering, Case Western Reserve University, 1999
  • BS Chemical Engineering, Case Western Reserve University, 1992
  • ISMRM Annual Meeting Program Committee, 2011-2014
  • Reviewer with Distinction – Magnetic Resonance in Medicine
  • Senior Author – Semi-Finalist for ISMRM Young Investigator Award, 2013
  • Chair – CWRU School of Medicine Core Steering Committee
  • Associate Faculty Representative: Department of Biomedical Engineering
  1. Preclinical MR fingerprinting (MRF) at 7 T: effective quantitative imaging for rodent disease models. NMR Biomed. 2015 Mar;28(3):384-94. doi: 10.1002/nbm.3262. Epub 2015 Feb 2. PMID: 25639694
  2. Lipid elimination with an echo-shifting N/2-ghost acquisition (LEENA) MRI. Magn Reson Med. 2015 Feb;73(2):711-7. doi: 10.1002/mrm.25177. Epub 2014 Mar 17.
  3. Arterial spin labeling-fast imaging with steady-state free precession (ASL-FISP): a rapid and quantitative perfusion technique for high-field MRI. NMR Biomed. 2014 Aug;27(8):996-1004. doi: 10.1002/nbm.3143. Epub 2014 Jun 3. PMID: 24891124
  4. Normalized t1 magnetic resonance imaging for assessment of regional lung function in adult cystic fibrosis patients - a cross-sectional study. PLoS One. 2013.
  5. Diffusion-prepared fast imaging with steady-state free precession (DP-FISP): a rapid diffusion MRI technique at 7 T. Magn Reson Med. 2012.
  6. Measuring in vivo tumor pHe with CEST-FISP MRI. Magn Reson Med. 2012.
  7. Use of diffusion tensor MRI to identify early changes in diabetic nephropathy. American  Journal of  Nephrology 2011.
  8. Body composition analysis of obesity and hepatic steatosis in mice by relaxation compensated fat fraction (RCFF) MRI. Journal of Magnetic Resonance Imaging. 2012.