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Nicole Steinmetz, PhD

Associate Professor, Biomedical Engineering; Secondary appointments: Radiology; Materials Science and Engineering, Macromolecular Science and Engineering 216.368.4377 (o)

Case Western Reserve University School of Medicine
Biomedical Research Building, Room 333
10900 Euclid Avenue
Cleveland, OH 44106

Research Interests

  • Medical research
  • Bio-inspired materials science
  • Plant virus-based nanoparticles
  • Nanomaterials
  • Drug delivery
  • MRI contrast agents
  • Targeted therapeutics
  • Immunotherapies
  • Breast, prostate, ovarian and colon cancer
  • Cardiovascular disease

  • AHA and NIH postdoctoral fellow, The Scripps Research Institute, La Jolla, CA, 2007-2010
  • Marie Curie EST fellow, PhD, Bionanotechnology, John Innes Centre, UK, 2004-2007
  • Diploma (equivalent to MS), Molecular Biotechnology, RWTH-Aachen University, Germany, 2004
  • Chair, Gordon Conference of Physical Virology, 2015
  • Session Chair, Protein and Viral Nanoparticle Track, FNANO, current
  • Editorial Board Member, Wiley Interdisciplinary Reviews (WIREs), current
  • Advisory Editorial Board Member, ACS journal, Molecular Pharmaceutics, current
  • Mt. Sinai Scholar, 2011
  • NIH/NIBIB Pathway to Independence Grant, 2009-2013
  • American Heart Association postdoctoral fellow, 2008-2009
  • Marie Curie EST fellow, 2004-2007
  1. Design rules for nanomedical engineering: from physical virology to the applications of virus-based materials in medicine. J Biol Phys. 2013 Mar;39(2):301-25. doi: 10.1007/s10867-013-9314-z. Epub 2013 Apr 19.
  2. Interior engineering of a viral nanoparticle and its tumor homing properties. Biomacromolecules. 2012 Dec 10;13(12):3990-4001. doi: 10.1021/bm301278f. Epub 2012 Nov 14.
  3. Infusion of imaging and therapeutic molecules into the plant virus-based carrier cowpea mosaic virus: cargo-loading and in vitro delivery. J Control Release. 2013 Dec 10;172(2):568-78. doi: 10.1016/j.jconrel.2013.04.023. Epub 2013 May 9.
  4. Increased tumor homing and tissue penetration of the filamentous plant viral nanoparticle potato virus X. Mol Pharm. 2013 Jan 7;10(1):33-42. doi: 10.1021/mp300240m. Epub 2012 Jul 9.
  5. Intravital Imaging of Human Prostate Cancer Using Viral Nanoparticles Targeted to Gastrin-Releasing Peptide Receptors. Small. 2011 Jun 20;7(12):1664-72. doi: 10.1002/smll.201000435. Epub 2011 Apr 26. *Cover article