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Raymond F. Muzic, Jr., PhD

Professor, Radiology; Secondary Appointments: Biomedical Engineering and Oncology 216.844.3543 (o)

Department of Radiology
Case Western Reserve University
Mail Stop: BSH 5056
11100 Euclid Avenue
Cleveland, OH 44106

Research Interests

  • Quantitative imaging, analysis and modeling, optimal experiment design
  • Metabolic imaging
  • Cancer imaging
  • Cardiovascular imaging

Dr. Muzic's research spans multiple therapeutic areas including cancer, cardiac, and diabetes research. His research works includes quantitative analysis of biomedical imaging data, physiologic modeling, optimal experiment design, assessment of new radiopharmaceuticals, imaging response to therapy, and in vivo quantification of receptor concentration. His work also includes creation and dissemination of COMKAT software for quantitative analysis of biomedical image data, and is used to support research and teaching.


Dr. Muzic is the Scientific Director of the Quantitative Imaging Laboratory. To learn more visit

  • PhD, Biomedical Engineering, Case Western Reserve University, 1991
  • MS, Biomedical Engineering, Case Western Reserve University, 1988
  • BS, Biomedical Engineering, Case Western Reserve University, 1987
  • Teacher of the Year, Radiologic Physics, University Hospitals Case Medical Center, 2010
  • Teacher of the Year, Non-interpretive skills, Department of Radiology, University Hospitals Case Medical Center, 2007
  • Engineer of the Year, IEEE Cleveland Section, 2001
  • Graduated with Highest Honors, Case Western Reserve University, 1987
  1. k-space sampling optimization for ultrashort TE imaging of cortical bone: applications in radiation therapy planning and MR-based PET attenuation correction. Med Phys. 2014 Oct;41(10):102301. doi: 10.1118/1.4894709.
  2. Dexamethasone-induced insulin resistance: kinetic modeling using novel PET radiopharmaceutical 6-deoxy-6-[(18)F]fluoro-D-glucose. Mol Imaging Biol. 2014 Oct;16(5):710-20. doi: 10.1007/s11307-014-0737-0.
  3. Optimized dynamic framing for PET-based myocardial blood flow estimation.Phys Med Biol. 2013 Aug 21;58(16):5783-801. doi: 10.1088/0031-9155/58/16/5783. Epub 2013 Aug 2.
  4. Simultaneous magnetic resonance angiography and perfusion (MRAP) measurement: Initial application in lower extremity skeletal muscle.J Magn Reson Imaging. 2013 Nov;38(5):1237-44. doi: 10.1002/jmri.24020. Epub 2013 Feb 6.
  5. Hyperglycemia-induced stimulation of glucose transport in skeletal muscle measured by PET-[18F]6FDG and [18F]2FDG.Physiol Meas. 2012 Oct;33(10):1661-73. Epub 2012 Sep 18.