Our Latest News

Case Comprehensive Cancer Center Director Elected Senior Member of the National Academy of Inventors

August 13, 2019

The National Academy of Inventors (NAI) has named 54 academic inventors to the Spring 2019 class of NAI Senior Members, including Stanton L. Gerson, MD, Director of the Case Comprehensive Cancer Center (Case CCC).

A New Pathway: Researchers Identify Potential Treatment Target for Crohn’s Disease

August 8, 2019

There is no cure for the more than 1.6 million people in the United States living with Crohn’s disease (CD) and its symptoms, including abdominal pain, intestinal distress and severe weight-loss. CD is a form of inflammatory bowel disease (IBD) in which the body’s own immune system attacks the gastrointestinal tract, and treatment is focused on controlling the symptoms of the disease in its acute phase and managing it in remission.

Case Western Reserve School of Medicine Scientist Receives Major Grant for Diagnosis of Alzheimer’s, Parkinson’s Via New Skin Test

August 2, 2019

Wenquan Zou, MD, PhD, an expert in prion and degenerative neurological diseases, has received a two-year grant for developing diagnostic tools for Alzheimer’s disease, Parkinson’s disease, and other related brain-based degenerative disorders via an innovative skin test that uses ultrasensitive technology. The new test is much less invasive than evaluating brain tissue, which is the only approach for making a definitive diagnosis today.

Researchers Discover New Combination Therapy to Treat Drug-Resistant Acute Lymphoblastic Leukemia

July 29, 2019

Acute lymphoblastic leukemia accounts for one in five adult leukemias, and is the most common pediatric cancer in the United States. While new immune therapies have helped improve survival rates, some patients are unresponsive to existing treatment regimens. In addition, drug-related toxicities and drug resistance are rampant for these patients, spurring an urgent need for new therapy options.

How do Interactions between Gut Bacteria and Fungi Exacerbate Crohn’s Disease?

July 25, 2019

Scientists have known that bacteria in the gut, along with environmental and genetic factors, contribute to the debilitating intestinal ailment of Crohn’s disease (CD). But in 2016, Mahmoud A Ghannoum, PhD, FAAM, FIDSA, professor and director of the Center for Medical Mycology at Case Western Reserve School of Medicine and University Hospitals Cleveland Medical Center, was the first to identify a specific fungus in humans that interacted with bacteria in the development of the disease.

New, High-Resolution Images Reveal Clues to Improve Anti-Nausea Drugs for Cancer Patients

July 19, 2019

A new study using a special type of electron microscope using samples cooled to extremely cold temperatures provides critical information for drug developers seeking to reduce nausea and vomiting side effects of cancer treatments.

Mosquito Surveillance Uncovers New Information about Malaria Transmission in Madagascar

July 11, 2019

Riley Tedrow, PhD, a medical entomologist at Case Western Reserve University School of Medicine, has uncovered new findings about malaria transmission in Madagascar. In a recent study published in PLoS Neglected Tropical Diseases, he also describes real-world application of an effective mosquito surveillance strategy using low cost traps and a recently reported tool that simultaneously tests each mosquito for its species, what it fed on, and the presence of malaria parasites.

Keeping Do-It-Yourself Gene Science Safe

July 9, 2019

While federal and professional regulatory systems monitor genetic-editing experiments in university and corporate labs, most research conducted outside of these settings lacks formal oversight.

Combining Antibiotics, Researchers Deliver One-Two Punch against Ubiquitous Bacterium

July 8, 2019

By combining two well-established antibiotics for the first time, a scientific team led by Case Western Reserve University School of Medicine and Louis Stokes Cleveland VA Medical Center has delivered a “double whammy” against the pervasive Pseudomonas aeruginosa, a potentially deadly form of bacteria that is a major source of hospital-based infections.

Drug to Treat Malaria Could Mitigate Hereditary Hearing Loss

June 11, 2019

The ability to hear depends on proteins to reach the outer membrane of sensory cells in the inner ear. But in certain types of hereditary hearing loss, mutations in the protein prevent it from reaching these membranes. Using a zebrafish model, researchers at Case Western Reserve University School of Medicine have found that an anti-malarial drug called artemisinin may help prevent hearing loss associated with this genetic disorder.

“Giving Kids Hope” Event Benefits Research on Genetic Disorders Affecting Children

June 3, 2019

Case Western Reserve University School of Medicine will host the fourth annual Giving Kids Hope benefit to help fund research in pediatric genetic disorders, on Saturday, June 8, at 6 p.m. The exciting evening will take place at the newly renovated Agora Theatre and Ballroom, and will be emceed by WKYC-TV Senior Health Correspondent Monica Robins, with Cash Explosion host David McCreary as entertainment auctioneer.

Cleveland Researchers Recruiting for Alzheimer’s Disease Clinical Trial

May 28, 2019

Case Western Reserve University School of Medicine and University Hospitals (UH) Cleveland Medical Center have enrolled their first participant in a new clinical research study evaluating the potential benefits of an investigational medicine for people with early onset Alzheimer’s disease.

Key Drug Target Shown Assembling in Real-Time

May 20, 2019

Over one-third of all FDA-approved drugs act on a specific family of proteins: G-protein coupled receptors (GPCRs). Drugs to treat high blood pressure, asthma, cancer, diabetes and myriad other conditions target GPCRs throughout the body—but a recent study shows what happens next. In results published in Cell, researchers outline the timeline of events, including precisely when and how different parts of a GPCR interacts with its G protein signaling partners.

Case Comprehensive Cancer Center Awarded Nearly $9 Million to Expand Access to Clinical Trials

May 16, 2019

Case Comprehensive Cancer Center has been selected, once again, as a Lead Academic Participating Site by the National Cancer Institute. The renewal comes with a six-year, $8.9 million grant that will enable the center to provide patients with additional access to clinical trials through the National Clinical Trials Network. In this renewal, NCI is committed to improving the resources provided for each patient to cover research costs at levels linked to the complexity of the clinical trial.

“The Race” 5K and 1-Mile Run Benefits Breast Cancer Research on Mother’s Day, May 12

April 30, 2019

The 16th annual family-friendly “The Race” will take place this Mother’s Day, Sunday, May 12, at Legacy Village in Lyndhurst. Registration begins at 7:30 a.m. and the 5K starts at 8:30 a.m., followed by the 1-mile run at 9:30 a.m.