Dr. Daniel Tisch has two decades’ experience as an epidemiologist, biostatistician, and data core director in field studies of parasitic diseases in the South Pacific and Africa. He has been active in the development of education and training in epidemiology, biostatistics, and databases in low-resource settings such as Papua New Guinea. His primary research focus is the monitoring and elimination of lymphatic filariasis, a debilitating disease transmitted to humans by mosquitoes. He is also actively involved in research on diagnostics and epidemiology of malaria, schistosomiasis, and integrated parasite control programs. He specializes in the application of modern epidemiologic and statistical techniques to the design and analysis of cluster randomized field trials and observational studies.
Epidemiology of lymphatic filariasis, malaria, and schistosomiasis. Parasite control and elimination. Design and evaluation of diagnostics, monitoring tools, and disease elimination strategies.
Awards and Honors
- Ome-Kaius, M, Kattenberg, JH, Zaloumis, S, Siba, M, Kiniboro, B, Jally, S, Razook, Z, Mantila, D, Sui, D, Ginny, J, Rosanas-Urgell, A, Karl, S, Obadia, T, Barry, A, Rogerson, SJ, Laman, M, Tisch, D, Felger, I, Kazura, JW, Mueller, I, Robinson, LJ. Differential impact of malaria control interventions on P. falciparum and P. vivax infections in young Papua New Guinean children. BMC Med 2019; 17 (1): 220. PubMed PMID:31813381 PubMed Central PMC6900859.
- Quah, YW, Waltmann, A, Karl, S, White, MT, Vahi, V, Darcy, A, Pitakaka, F, Whittaker, M, Tisch, DJ, Barry, A, Barnadas, C, Kazura, J, Mueller, I. Molecular epidemiology of residual Plasmodium vivax transmission in a paediatric cohort in Solomon Islands. Malar. J. 2019; 18 (1): 106. PubMed PMID:30922304 PubMed Central PMC6437916.
- Berg Soto, A, Xu, Z, Wood, P, Sanuku, N, Robinson, LJ, King, CL, Tisch, D, Susapu, M, Graves, PM. Combining different diagnostic studies of lymphatic filariasis for risk mapping in Papua New Guinea: a predictive model from microfilaraemia and antigenaemia prevalence surveys. Trop Med Health 2018; 46 : 41. PubMed PMID:30533996 PubMed Central PMC6280391.
- Howes, RE, Franchard, T, Rakotomanga, TA, Ramiranirina, B, Zikursh, M, Cramer, EY, Tisch, DJ, Kang, SY, Ramboarina, S, Ratsimbasoa, A, Zimmerman, PA. Risk Factors for Malaria Infection in Central Madagascar: Insights from a Cross-Sectional Population Survey. Am. J. Trop. Med. Hyg. 2018; 99 (4): 995-1002. PubMed PMID:30182923 PubMed Central PMC6159596.
- Guo, S, He, L, Tisch, DJ, Kazura, J, Mharakurwa, S, Mahanta, J, Herrera, S, Wang, B, Cui, L. Pilot testing of dipsticks as point-of-care assays for rapid diagnosis of poor-quality artemisinin drugs in endemic settings. Trop Med Health 2016; 44 : 15. PubMed PMID:27433134 PubMed Central PMC4940968.
- Small, ST, Reimer, LJ, Tisch, DJ, King, CL, Christensen, BM, Siba, PM, Kazura, JW, Serre, D, Zimmerman, PA. Population genomics of the filarial nematode parasite Wuchereria bancrofti from mosquitoes. Mol. Ecol. 2016; 25 (7): 1465-77. PubMed PMID:26850696 PubMed Central PMC4808423.
- Small, ST, Tisch, DJ, Zimmerman, PA. Molecular epidemiology, phylogeny and evolution of the filarial nematode Wuchereria bancrofti. Infect. Genet. Evol. 2014; 28 : 33-43. PubMed PMID:25176600 PubMed Central PMC4257870.
- Small, ST, Ramesh, A, Bun, K, Reimer, L, Thomsen, E, Baea, M, Bockarie, MJ, Siba, P, Kazura, JW, Tisch, DJ, Zimmerman, PA. Population genetics of the filarial worm wuchereria bancrofti in a post-treatment region of Papua New Guinea: insights into diversity and life history. PLoS Negl Trop Dis 2013; 7 (7): e2308. PubMed PMID:23875043 PubMed Central PMC3708868.
- Moormann, AM, Sumba, PO, Chelimo, K, Fang, H, Tisch, DJ, Dent, AE, John, CC, Long, CA, Vulule, J, Kazura, JW. Humoral and cellular immunity to Plasmodium falciparum merozoite surface protein 1 and protection from infection with blood-stage parasites. J. Infect. Dis. 2013; 208 (1): 149-58. PubMed PMID:23539744 PubMed Central PMC3666139.
- Dent, AE, Moormann, AM, Yohn, CT, Kimmel, RJ, Sumba, PO, Vulule, J, Long, CA, Narum, DL, Crabb, BS, Kazura, JW, Tisch, DJ. Broadly reactive antibodies specific for Plasmodium falciparum MSP-1(19) are associated with the protection of naturally exposed children against infection. Malar. J. 2012; 11 : 287. PubMed PMID:22909378 PubMed Central PMC3502150.
Metrics from Web of Science/publons and Scopus/SciVal:
- H-index: 21
- Total publications from CV: 48
- Total citations: 685
- Publications in top-tier journals: 41 %
- Collaborative publishing national/international: 33%/67%
- American Journal of Tropical Medicine and Hygiene, biostatistical editor
Contributions to science
- Epidemiology of lymphatic filariasis elimination
- Molecular epidemiology of lymphatic filariasis
- Epidemiology of malaria
- NIH/NIAID R01: Asymptomatic malaria gametocyte levels in Kenya: An observational survey
- Washington University in St. Louis: Objective B clinical trials of new regimens and dosing schedules to identify more effective therapies for filariasis and onchocerciasis
Student and mentee totals, over Case Western Reserve University career:
- Master’s: 150
- PhD: 2
- PhD graduates’ current careers:
- Makerere University, faculty
- Post-doctoral Training
Teaching and training, International:
- Course Director: Epidemiology and Biostatistics, (Papua New Guinea Institute for Medical Research, Goroka, Papua New Guinea)
- Faculty: Epidemiology of Infectious Disease (Papua New Guinea Institute for Medical Research)
- Course Director: Epidemiology and Biostatistics (Papua New Guinea Institute for Medical Research)
- Director: Field Training on Dengue Surveillance (Bahai, Brazil, Federal University of Bahia, Brazil)
- Director: Field Training on Dengue (Puerto Rico and Florida, CDC)
- Director: Field Survey Research Training (Key West Florida, CDC and Monroe, Florida Department of Health)