Abdus Sattar, PhD

Associate Professor
Department of Population and Quantitative Health Sciences
School of Medicine

Dr. Sattar is an expert in complex longitudinal studies. He is developing new biostatistical methods for the analysis of longitudinal and survival studies motivated by his own clinical study experiences. He has contributed to research on multiple chronic conditions by developing study designs and analytical methods. His research interests include random-effects survival models, joint modeling of outcomes, Bayesian semiparametric regression for high-dimensional longitudinal data, and dynamic treatment regimens (Q-learning).

Personal Web page:

http://sattar.case.edu

Teaching Information

Courses Taught

EPBI 430. Design and Analysis of High-Dimensional Data
EPBI 443. Multivariate and High-Dimensional Data Analysis
EPBI 485. Likelihood Theory and Applications
Categorical Data Analysis
Biostatistics Seminar
Computational Neuroimaging

Research Information

Research Interests

Statistical Methods:

  • Longitudinal data analysis
  • Frailty models for time-to-event data
  • Joint modeling of longitudinal and survival data
  • Semiparametric and nonparametric methods for longitudinal data
  • Statistical methods for gene expression and next generation sequencing data

Clinical Research:

  • Multiple chronic conditions

Awards and Honors

Travel Support
2012
ENAR Workshop for Junior Investigators
Bursary Service Award
2011
University of Alabama
International Educational Scholarship
2003
Texas A&M U
First Class First in B.S. Degree (Equivalent to Summa Cum Laude)
1996
Merit Scholarship
1995
Jahangirnagar University

Professional Memberships

American Statistical Association, invited sessions chair
International Biometric Society Eastern North American Region, invited sessions chair
Statistical Society of Canada
Bangladesh Statistical Association

Publications

Recent Publications

  • Dirajlal-Fargo, S, Albar, Z, Bowman, E, Labbato, D, Sattar, A, Karungi, C, Nazzinda, R, Funderburg, N, Kityo, C, Musiime, V, McComsey, GA. Increased monocyte and T-cell activation in treated HIV+ ugandan children: associations with gut alteration and HIV factors. AIDS 2020; : . PubMed PMID:32073452 .
  • Dirajlal-Fargo, S, Shan, L, Sattar, A, Kulkarni, M, Bowman, E, Funderburg, N, Nazzinda, R, Karungi, C, Kityo, C, Musiime, V, Mccomsey, GA. Micronutrients, Metabolic Complications and Inflammation in Ugandan Children with HIV. J. Pediatr. Gastroenterol. Nutr. 2020; : . PubMed PMID:31939864 .
  • Dirajlal-Fargo, S, Albar, Z, Bowman, E, Labbato, D, Sattar, A, Karungi, C, Longenecker, CT, Nazzinda, R, Funderburg, N, Kityo, C, Musiime, V, McComsey, GA. Subclinical Vascular Disease in Children with HIV in Uganda is Associated with Intestinal Barrier Dysfunction. Clin. Infect. Dis. 2019; : . PubMed PMID:31807748 .
  • Dirajlal-Fargo, S, Shan, L, Sattar, A, Bowman, E, Gabriel, J, Kulkarni, M, Funderburg, N, Nazzinda, R, Musiime, V, McComsey, GA. Insulin resistance and intestinal integrity in children with and without HIV infection in Uganda. HIV Med. 2020; 21 (2): 119-127. PubMed PMID:31642582 PubMed Central PMC6980894.
  • Dirajlal-Fargo, S, Yu, J, Kulkarni, M, Sattar, A, Funderburg, N, Barkoukis, H, Mccomsey, GA. Brief Report: Zinc Supplementation and Inflammation in Treated HIV. J. Acquir. Immune Defic. Syndr. 2019; 82 (3): 275-280. PubMed PMID:31609926 PubMed Central PMC6812547.
  • Winkelman, C, Sattar, A, Momotaz, H, Johnson, KD, Morris, P, Feeney, S, Levine, A. Early Therapeutic Mobility and Changes in Scores for Pain and Fatigue. Crit Care Nurse 2019; 39 (5): 30-36. PubMed PMID:31575592 PubMed Central PMC6849204.
  • Moses, J, Lambert-Jenkins, K, Momotaz, H, Sattar, A, Debanne, SM, Splawski, J, Sferra, TJ. Time to antibody detection and associated factors for presence of anti-drug antibodies in pediatric inflammatory bowel disease patients treated with anti-TNF therapy. Eur J Gastroenterol Hepatol 2019; 31 (10): 1228-1233. PubMed PMID:31498282 .
  • Horvat Davey, C, Perazzo, JD, Vest, M, Josephson, RA, Oliveira, VHF, Sattar, A, Webel, AR. The relationship of cardiorespiratory function, fatigue and depressive symptoms in PLHIV. AIDS Care 2019; : 1-5. PubMed PMID:31470737 PubMed Central PMC7048664.
  • Toly, VB, Sattar, A, Zauszniewski, JA. Maternal Factors Associated With the Healthcare Utilization of Technology-Dependent Infants Following NICU Discharge. J Perinat Neonatal Nurs ; 33 (3): 268-275. PubMed PMID:31335857 .
  • Dirajlal-Fargo, S, El-Kamari, V, Weiner, L, Shan, L, Sattar, A, Kulkarni, M, Funderburg, N, Nazzinda, R, Karungi, C, Kityo, C, Musiime, V, McComsey, GA. Altered intestinal permeability and fungal translocation in Ugandan children with HIV. Clin. Infect. Dis. 2019; : . PubMed PMID:31260509.
  • Darrah, RJ, Jacono, FJ, Joshi, N, Mitchell, AL, Sattar, A, Campanaro, CK, Litman, P, Frey, J, Nethery, DE, Barbato, ES, Hodges, CA, Corvol, H, Cutting, GR, Knowles, MR, Strug, LJ, Drumm, ML. AGTR2 absence or antagonism prevents cystic fibrosis pulmonary manifestations. J. Cyst. Fibros. 2018; : . PubMed PMID:29937318 .
  • Winkelman, C, Sattar, A, Momotaz, H, Johnson, KD, Morris, P, Rowbottom, JR, Thornton, JD, Feeney, S, Levine, A. Dose of Early Therapeutic Mobility: Does Frequency or Intensity Matter? Biol Res Nurs 2018; : 1099800418780492. PubMed PMID:29902939 .
  • Wright, KD, Moore-Schiltz, L, Sattar, A, Josephson, R, Moore, SM. Does Lifestyle Exercise After a Cardiac Event Improve Metabolic Syndrome Profile in Older Adults? J Cardiovasc Nurs ; 33 (3): E1-E9. PubMed PMID:29634648 PubMed Central PMC5922456.
  • Webel, AR, Moore, SM, Longenecker, CT, Currie, J, Horvat Davey, C, Perazzo, J, Sattar, A, Josephson, RA. Randomized Controlled Trial of the SystemCHANGE Intervention on Behaviors Related to Cardiovascular Risk in HIV+ Adults. J. Acquir. Immune Defic. Syndr. 2018; 78 (1): 23-33. PubMed PMID:29373392 PubMed Central PMC5889354.
  • Webel, AR, Perazzo, J, Longenecker, CT, Jenkins, T, Sattar, A, Rodriguez, M, Schreiner, N, Josephson, RA. The Influence of Exercise on Cardiovascular Health in Sedentary Adults With Human Immunodeficiency Virus. J Cardiovasc Nurs ; 33 (3): 239-247. PubMed PMID:29189426 PubMed Central PMC5893400.
  • Dirajlal-Fargo, S, El Kamari, V, Sattar, A, Alam, K, Funderburg, N, Labbato, D, Pirro, L, Longenecker, CT, Wilson, WH, McComsey, GA. Effect of statin on arginine metabolites in treated HIV-infection. Atherosclerosis 2017; 266 : 74-80. PubMed PMID:28992467 PubMed Central PMC5671899.
  • Sattar, A, Sinha, SK. Joint modeling of longitudinal and survival data with a covariate subject to a limit of detection. Stat Methods Med Res 2017; : 962280217729573. PubMed PMID:28956504 .
  • Dirajlal-Fargo, S, Sattar, A, Kulkarni, M, Funderburg, N, McComsey, GA. Soluble TWEAK may predict carotid atherosclerosis in treated HIV infection. HIV Clin Trials 2017; 18 (4): 156-163. PubMed PMID:28828963 .
  • Sattar, A. A Response to Predictors of Heart Disease Knowledge Among Older and Younger Asian Indian Adults. J Immigr Minor Health 2018; 20 (2): 261-262. PubMed PMID:28616761 .
  • Ascha, M, Kurlander, DE, Sattar, A, Gatherwright, J, Guyuron, B. In-Depth Review of Symptoms, Triggers, and Treatment of Occipital Migraine Headaches (Site IV). Plast. Reconstr. Surg. 2017; 139 (6): 1333e-1342e. PubMed PMID:28538577 .

Publishing impact 

Metrics from Web of Science/publons and Scopus/SciVal: 

  • H-index: 15 
  • Total publications: 83 
  • Total citations:  590 
  • Publications in top-tier journals: 13%
  • Collaborative publishing national/international: 75%/13%

Editorial roles:

  • Statistical Methods in Medical Research, editorial board and associate editor
  • Journal of Immigrant and Minority Health, associate editor

Education

Doctor of Philosophy
Biostatistics
University of Pittsburgh
2009
Master of Science
Mathematics
Texas A&M University
2004
Master of Science
Statistics
Texas A&M University
2003

Residencies, Internships and Fellowships

Learning Fellowship
2013
Mentor Fellowship
Case Western Reserve University
2012
Travel Fellowship, Short Course on Statistical Genetics and Genomics
University of Alabama
2011

Additional Information

Related Sites:

Department of Population and Quantitative Health Sciences

Contributions to science:

  • Biostatistical methods for longitude and survival data subject to complex issues of non-ignorable missing, limit of detection problem, and outliers
  • Semiparametric spline mixed models, joint modeling of longitudinal and survival data 
  • HIV/AIDS, cardiovascular diseases, premature infants’ health, technologically dependent children, adolescent, self-management, and multiple chronic conditions, and multiple sclerosis. 

Active grants:

  • NIH/NIDDK R01: Effects of GLP-1 receptor agonists on cardiometabolic alteration in HIV-associated lipohypertrophy
  • PCORI: Comparing the Effectiveness of Fatigue Management Programs for People with MS
  • NIH/NINR R15: Resourcefulness Intervention for Mothers of Technology-Dependent Children
  • NIH/NICHD K23: Cardiovascular disease and inflammation in Ugandan children with HIV
  • NIH/NINR 1 T32: Multiple Chronic Conditions Interdisciplinary Nurse Scientist Training
  • NIH/NINR 5 R21: Structure & Function of Dopaminergic Brain Networks following Postnatally-Occurring Hypoxic Insults 
  • NIH/NINR 5 P30: SMART Center II: Brain-Behavior Connections in Self-Management Science