Rafick-Pierre Sékaly, PhD

Department of Pathology
School of Medicine
Hematopoietic and Immune Cancer Biology Program
Case Comprehensive Cancer Center

Research Information

Research Interests

My group has been focused for the past 20 years on developing a better understanding of the human immune response to vaccines and to chronic viral infections with a specific focus on cancer and HIV infection. Over the past seven years, we have implemented the use of system biology approaches to monitor the diversity of memory T cell and to identify the mechanisms underlying the diversity of memory T cell subsets. Our group has also pioneered the application of systems biology approaches to the understanding of mechanisms of action of the licensed vaccines and adjuvants; lastly our group has also shown for the first time the diversity of the mechanism that lead to the establishment and persistence of different memory T cell subsets.