CONTACT INFORMATION
Phone: (216) 368-4067 |
Fax: (216) 368-4969 |
Email: sje@case.edu |
Office: Wickenden Building Room 203, 10900 Euclid Ave, Cleveland, OH 44106-7207 |
EDUCATION
Ph.D. in Physics Case Western Reserve University
B.A. in Physics Carleton College |
ACTIVE RESEARCH
Nanoscale Orthopedic Biomaterials
Fabricating nanophase collagen/mineral materials intended to mimic bone structure at the submicron scale. These materials are designed to interact in a natural way with the cells normally found in human bone providing short term load bearing capacity with mid to long term bioresorbability. |
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Submolecular Scale Physical Interactions
Mapping properties like static charge, dipole moments, and electronic polarizability onto measured three dimensional molecular structures. Developing techniques that utilize these enriched structural images in the creation of models intended to predict assembly of supramolecular structures as well as the mechanics of these structures.
POTENTIAL IMPACT
Our approach will yield insight into a host of biologically relevant problems ranging from enzyme-substrate interactions to design and synthesis of novel biomaterials to whole tissue mechanics.
SELECTED PUBLICATIONS
S.J. Eppell, B.N. Smith, H. Kahn, R. Ballarini, “Nano Measurements With Micro Devices: mechanical properties of hydrated collagen fibrils,” Journal of the Royal Society Interface, 3, No. 6, pp. 117-121 (2006).
B. A. Todd, J. Rammohan, S. J. Eppell, “Connecting Nanoscale Molecular Images of Proteins with their Genetic Sequences,” Biophysical Journal, 84, No. 6, 3982-3991 (2003)
FIELDS
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