CONTACT INFORMATION
| Phone: (216) 368-0187 |
| Fax: (216) 368-4969 |
| Email: young.kwon@case.edu |
Office: Wickenden 523, 10900 Euclid Avenue, Cleveland, OH 44106-7207
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EDUCATION
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Ph.D. in Chemical Engineering University of Southern California
M.S. Chemical Engineering University of Southern California
B.S. in Biologial Engineering Inha University, Korea |
ACTIVE RESEARCH
Cancer Nanomedicine
Investigating nanocarriers for cancer-targeted delivery of chemotheray agents; Controlled and localized release of co-delivered chemotherapy agents and enhancing molecules; In vivo imaging of the carriers to examine fates of the drugs in the body; develping a cancer vaccine to activate and control immine responses using nanocarriers |
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Gene Therapy
sthesizing semi-artifical viral and polymeric vectors; functionalizing gene carriers for in vivo imaging, specific targeting, and easy preparation
Cell Therapy and Stem Cell Engineering
preapring stem cells of higher purity at large scale using bioreactors; genetically modifying stem cells for cell therapy; labeling cells for monitoring their in vivo behavior.
POTENTIAL IMPACT
This highly multi-disciplinary research focuses on therapeutic applications of nanotechnology. New nanomedicine will enable us to find efective ways of understanding, diagnosing, preventing, and treating many challenging diseases such as cancer, and inherited and acquired genetic disorders.
SELECTED PUBLICATIONS
Young Jik Kwon, Edward James, Nilabh Shastri, Jean M. J. Fréchet. Efficient cytotoxic T lymphocyte-mediated immunization by in vivo dendritic cell targeting with acid-degradable polymeric particle carriers.
Proceedings of the National Academy of Sciences in USA, 102, 18264-18268 (2005) Young Jik Kwon, Gene Hung, W. French Anderson, Ching-An Peng, and Hong Yu. Determination of Infectious retrovirus concentration from colony-forming assay with quantitative analysis. Journal of Virology 77, 5712-5720 (2003)
FIELDS
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