IRB + Research Compliance
Research Study Compliance
For your convenience, below is information about the IRB. Forms and processes for IRB submission are online. An overview on regulatory binder preparation and maintenance can be found in a presentation delivered by Drs. Sara Douglas and Amy Lipson. Learn more >
Frances Payne Bolton School of Nursing research projects involving human subjects are required to obtain IRB approval from a "home" institution (in most cases, CWRU or UH) before the start of any research activities. Use the information below to learn about the purpose of IRBs and how to get started on your submission for IRB approval.
It is vital that IRB policies are followed, as violations may have serious consequences, including termination of research and disciplinary actions.
Institutional Review Boards are committees of scientific experts, employees, faculty members, and community representatives who are responsible for reviewing human subjects research conducted at a given institution. For students, please note that while a student may serve as the primary researcher, the IRB requires that a faculty advisor sign as the responsible/principle investigator with ultimate responsibility for human subject projection.
Submitting to the IRB
Investigators are responsible for submitting their studies to the appropriate IRBs for approval, as well as monitoring the progress of submissions and responding to IRB inquiries. Approval timeframes vary based upon IRB, type of submission, and nature of the research. Approval for an Initial Review Submission can be expected to take at least 4 weeks, with more accurate averages around 8-12 weeks.
While some research projects may not require IRB oversight, that decision can only be determined by the IRB.
IRB Frequently Asked Questions
Q: How do I submit to the IRB?
A: Submissions are completed electronically. The most common IRBs used by the School of Nursing, CWRU IRB and the UHCMC IRB, use an electronic program called iRIS. The programs are housed at different website, but contain similar processes.
Q: How do I obtain access to iRIS?
A: Both CWRU and UH iRIS programs are accessed with your CWRU username (e.g. abc123) and password.
CWRU iRIS - Access is activated by contacting the CWRU IRB directly via email or phone.
UH iRIS - Access is activated by an initial log-in to iRIS using your CWRU username and password. Once you have logged in, you must complete the "My Account Information" section on the left side under "My Assistant". Make sure the "Email Address" field is completed so you are able to receive any IRB correspondence.
Q: Do chart reviews need IRB approval?
A: Probably, Yes. Most Chart Review studies can fall under Expedited Review, and some may even be Exempt if they are not using any identifiable information. However, Chart Review applications still have to be submitted to the IRB, even when requesting exemption.
Q: Can Research Assistants and Students work on the IRB application and/or other submission forms?
A: Yes! While Research Assistants and Students should not submit forms for approval, they can help prepare applications and documents for submission.
Q: How long does it take to get IRB approval?
A: It depends on the study. Unfortunately, there are no guaranteed approval timeframes for IRB submission. Approval time generally depends on completeness of your application and the type of study. The best way to speed up the review process is to start early! To avoid delays during the review process, make sure the entire submission form has been completed and all required documents are attached. Provide timely responses to IRB correspondence and ask for assistance when needed.
Associate Dean for Research:
Assistant Dean for Research:
Assistant Dean for Research Administration:
Assistant Director of the Center for Research & Scholarship:
Sally Garrett Karyo