Akiko Maeda, M.D., Ph.D.


Akiko Maeda, M.D., Ph.D.
Assistant Professor
Case Western Reserve University
Department of Ophthalmology and Visual Sciences
2085 Adelbert Road, Institute of Pathology, Rm 115
Cleveland, Ohio 44106
Phone: (216) 368-0670 Fax: (216) 368-3171
Email: akiko.maeda@case.edu
Research Focus: Age-related macular degeneration (AMD)

Research Summary
I have engaged in a medical science research for 10 years to cure retinal degenerative diseases, because I have been very frustrated with a lack of treatment options for my patients with these retinal diseases. Neurodegenerative retinal diseases significantly affect quality of life for over 50 million people worldwide, including 4 million in the United States, and there is a drastic lack of therapies available to patients.

My research activity bridges between clinical and basic science application and consists of three main parts: (1) Studying the role of the visual retinoid cycle, which is a vitamin A recycling system in the eye. (2) Studying the pathogenic defects associated with disease-causing-mutations in retinal genes using transgenic mouse technology. (3) Development of new therapies for currently incurable retinal diseases. Pharmacologic applications, gene transfer therapy and cell-based therapy are tested on our animal models of ocular diseases. These studies involve biochemical, molecular biology, genetic manipulations and gene therapy approaches.

Lab Openings: A postdoctoral position is available to study retinal diseases using mouse models. We are seeking an energetic, highly motivated PhD, MD, or MD/PhD with solid publication record and experience in ophthalmic examinations, biochemistry, immunology, genetics, or neuroscience.