Silver Lab Personnel


Richard F. SilverRichard F. Silver, M.D.

Dr. Silver is a native of Washington, D.C. where received his doctoral degree from the George Washington University School of Medicine. He completed internship and residency training in Internal Medicine at the Columbia Presbyterian Medical Center in New York City and fellowship training in Pulmonary and Critical Care Medicine at the Johns Hopkins University in Baltimore, MD. Dr. Silver came to Cleveland in 1993 specifically to join the large group of tuberculosis researchers at CWRU and has been a member of the faculty of the Division of Pulmonary, Critical Care, and Sleep Medicine since 1995.

Dr. Silver's research has been sponsored by the Francis Family Foundation, the American Lung Association and American Thoracic Society, the National Heart Lung and Blood Institute of the NIH, and the U.S. Department of Veterans' Affairs Office of Research and Development. His findings have been published in the official journals of the American Association of Immunologists, the American Society for Microbiology, the Infectious Diseases Society of America, and the American Thoracic Society.

Contact information:

Richard F. Silver, M.D.
Division of Pulmonary, Critical Care and Sleep Medicine
CWRU School of Medicine
Biomedical Research Building, Rm. 327
Phone: (216) 368-1151
e-mail: rfs4@case.edu

Jessica WalrathJessica R. Jarvela (Walrath), M.S.

Jessica was born and raised in Cleveland and attended the University of Dayton where she received a BS in Biology in 2002. She joined Dr. Silver's laboratory in the fall of 2002 and has since taken on the roles of head laboratory science technician, research coordinator, and laboratory manager. In addition, Jessica serves as a research assistant for the CWRU Biosafety Level-3 facility located in the Biomedical Research Building.

While working in Dr. Silver's laboratory Jessica received her MS in Pathology from CWRU in 2008. Her thesis project investigated the the role of homing molecules in recruitment of CD4+ T-cells to the lung in recall responses to M. tuberculosis. This work received honorable mention at the 2007 Case Western Reserve Research Showcase, and was subsequently published in the American Journal of Respiratory Cellular and Molecular Biology (45: 24-30, 2011).

Contact information:

Jessica R. Jarvela (Walrath), M.S.
Division of Pulmonary, Critical Care and Sleep Medicine
CWRU School of Medicine
Biomedical Research Building, Rm. 347
Phone: (216) 368-0531
e-mail: jrw20@case.edu

Michelle MoyerMichelle Moyer, M.S.

Michelle is a native of Mentor, OH. She received her B.A. from the College of Wooster in Wooster, OH in 1994. as well as a Masters of Science degree in Biology from Case Western Reserve University in 1998. She has been involved in pulmonary research since 1994 and has had extensive experience in the use of animal models, particularly in the study of respiratory muscle function and responsiveness to phrenic nerve stimulation.

Since joining Dr. Silver’s lab in 2013, Michelle has taken primary responsibility for establishing a murine model of aerosol M. tuberculosis infection to assess the interaction between T-cell populations of the lung parenchyma and those of the airways. This work has led to a successful application for funding that will allow us to further clarify how lung airway cells accessible in humans via bronchoalveolar lavage do or do not reflect M. tuberculosis-specific immune responses elsewhere in the lung.

Contact information:

Michelle Moyer, M.S.
Division of Pulmonary, Critical Care and Sleep Medicine
CWRU School of Medicine
Biomedical Research Building, Rm. 347
Phone: (216) 368-0531
e-mail: mcm11@case.edu

Sara WeigelSara Weigel

The newest member of the laboratory, Sara, was raised in Poland, OH. She received B.A. and B.S. degrees (in Anthropology and Biology) from Youngstown State University in 2012. Her anthropology studies involved on-site excavation work in San Salvador Island in the Bahamas as well as in the Malloura Valley in Cyprus. Sara’s graduate studies in Anthropology at Kent State University involved comparison of the morphology of specific cerebral structures and neurons across various mammalian species. She also previously worked at Northeast Ohio Medical University researching the rapid evolution of body size in mice from Gough Island.

With an interest in returning to her roots in Biology, Sara joined the Silver lab in 2016. She has since been involved in both human and murine studies of local immune responses to M. tuberculosis within the lung, with a major focus on flow cytometry-based assessment of bronchoalveolar lavage cells in both species.

Contact information:

Sara Weigel, B.S.
Division of Pulmonary, Critical Care and Sleep Medicine
CWRU School of Medicine
Biomedical Research Building, Rm. 347
Phone: (216) 368-0531
e-mail: sxw699@case.edu

 


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