Medicine's Jonathan Stamler discusses research on enzyme that controls weight gain, cholesterol levels

No more dieting, just turn off the fat? Body has a switch to control weight gain, finds research. Here's how it works

The Economic Times: Jonathan Stamler, professor at the School of Medicine, discussed his research findings that highlight a promising new method for delivering oxygen to tissues damaged by disease by coupling nitric oxide—which dilates blood vessels—with the oxygen carrying molecule hemoglobin. Stamler, said nitric oxide normally suppresses fat production, and targeting a specific enzyme acting as a “fat switch” could lead to first-in-class therapies for obesity, cardiovascular disease and liver protection. Human trials are possible within 18 months, he noted.