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neurology

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Study using stem cells created from ALS patients identifies potential new target for treatment
CLEVELAND—Amyotrophic lateral sclerosis (ALS), known as Lou Gehrig’s disease, is an incurable neurological disorder affecting motor neurons—nerve cells in the brain and spinal cord that control voluntary muscle movement and breathing. Many ALS clinical trials, including those testing promising drug...
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Case Western Reserve University School of Medicine launches Institute for Glial Sciences
New center will target glial cells to treat neurological diseases Case Western Reserve University has established an Institute for Glial Sciences to advance research of glial cells and their critical role in the health and diseases of the nervous systems, including multiple sclerosis, Alzheimer’s, ...
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Medicine’s David Birnkrant’s work included in shortlist of neurology publications highlights
David Birnkrant, professor emeritus of pediatrics at the School of Medicine, co-edited and co-authored a collection of articles on “Specialty Care for the Patient with Duchenne Muscular Dystrophy” in 2018. The collection recently was included on a shortlist of highlights from 75 years of neurology p...
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Unraveling the origins of Alzheimer’s disease
Researchers find new hints that could explain how the disease spreads in human brains Case Western Reserve University researchers studying human prions—misfolded proteins that cause lethal and incurable diseases—have, for the first time, identified surface features responsible for the replication o...
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Medicine’s Heidi Moawad interviews neurologist for migraine podcast
Heidi Moawad, clinical assistant professor of medicine, interviewed Nina Riggins, a neurologist and researcher at the University of California Headache Center, for a podcast titled “Innovations in Migraine Research: 6 Questions.” They discussed current treatments for migraines and headaches—specif...
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Case Western Reserve researchers to examine the role of skin prions in fatal neurodegenerative human prion disease
$2.9M NIH grant focuses on transmission and diagnostic testing Affecting both people and animals, prion diseases are degenerative brain disorders that can debilitate or kill their victims. The most common form of prion disease affecting humans is sporadic Creutzfeldt-Jakob disease (sCJD). There are ...
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CWRU researchers conduct study of serotonin and epileptic seizures
A team of researchers from Case Western Reserve University and several other institutions published “Serum serotonin levels in patients with epileptic seizures” in Epilepsia. The aim of the study was to investigate epileptic seizure-induced changes in serum serotonin levels and whether there are pot...
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Case Western Reserve University School of Medicine researchers create first artificial human prion
Finding may shed added light on, offer treatment hope for brain-wasting diseases Case Western Reserve University School of Medicine researchers have synthesized the first artificial human prion, a dramatic development in efforts to combat a devastating form of brain disease that has so far eluded tr...
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Neurology’s Nuria Lacuey-Lecumberri wins pilot award for research in Sudden Unexpected Death in Epilepsy
Nuria Lacuey-Lecumberri, assistant professor of neurology, was named the recipient of the National Institute of Neurological Disorders and Stroke (NINDS) UCB Center for Sudden Unexpected Death in Epilepsy (SUDEP) Research Pilot award. This pilot program awards grants to national and international r...
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Unraveling how a brain works, block by high-tech block
Case Western Reserve University researchers modernizing cognitive skills testing to detect deficits, problem-solving strategies and more Psychologists have long used building blocks to assess cognitive skills. But researchers at Case Western Reserve University are embedding the blocks with technolog...