Jean F. Welter, MD, MSc, PhD

Center Associate Director
Research Associate Professor
Department of Biology
College of Arts and Sciences
Project Lead, TR&D-2
Bioreactor Core Facility
Skeletal Research Center

Interests: Tissue-engineering and cell-based therapies, bioreactor design, mechanobiology, bone transplantation, imaging, fluorescence spectroscopy, drug delivery.

View Dr. Welter's CV


Zhong, Y.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Glucose Availability Affects Extracellular Matrix Synthesis During Chondrogenesis In Vitro. Tissue Eng Part A. 2021 Jan 26. doi: 10.1089/ten.TEA.2020.0144. Online ahead of print. PMID: 33499734 

Somoza, R.A. and Welter, J.F.: Isolation of Chondrocytes from Human Cartilage and Cultures in Monolayer and 3D. Methods Mol Biol. 2021;2245:1-12. doi: 10.1007/978-1-0716-1119-7_1. PMID: 33315191 

Mansour, J.M.; Motavalli, M.; Bensusan, J.; Li, M.; Margevicius, S.; and Welter, J.F.: The nonlinear relationship between speed of sound and compression in articular cartilage: Measurements and modeling. J Mech Behav Biomed Mater. 2020 Oct;110:103923. doi: 10.1016/j.jmbbm.2020.103923. PMID: 32952604 

Dai, Y.; Xu, W.; Somoza, R.A.; Welter, J.F.; Caplan, A.I.; Liu, C.C.: An Integrated Multi-Function Heterogeneous Biochemical Circuit for High-Resolution Electrochemistry-Based Genetic Analysis. Angew Chem Int Ed Engl. 2020 Nov 9;59(46):20545-20551. doi: 10.1002/anie.202010648. PMID: 32835412 

Motavalli, M.; Jones, C.; Berilla, J.A.; Li, M.; Schluchter, M.D.; Mansour, J.M.; and Welter, J.F.: Apparatus and method for rapid detection of acoustic anisotropy in cartilage. Journal of Medical and Biological Engineering, 2020, 40:419–427. 

Dai, Y.; Somoza, R.A.; Wang, L.; Welter, J.F.; Li, Y.; Caplan, A.I.; and Liu, C.C.: Exploring the Trans-Cleavage Activity of CRISPR Cas12a (cpf1) for the Development of a Universal Electrochemical Biosensor. Angew Chem Int Ed Engl. 2019 Sep 30. doi: 10.1002/anie.201910772. [Epub ahead of print] 

Larson, B.L.; Yu, S.N.; Park, H.; Estes, B.T.; Moutos, F.T.; Bloomquist, C.J.; Wu, P.B.; Welter, J.F.; Langer, R.; Guilak, F.; and Freed, L.E.: Cartilaginous and osteochondral tissue formation by human mesenchymal stem cells on three-dimensionally woven scaffolds. Journal of Tissue Engineering and Regenerative Medicine. 2019 doi: 10.1002/anie.2019107722019 

Mansour, J.M.; Motavalli, M.; Dennis, J.E.; Kean, T.J.; Caplan, A.I.; Berilla, J.A.; and Welter, J.F.: Rapid detection of shear-induced damage in tissue engineered cartilage using ultrasound. Tissue engineering, part C, 24(8):443-456, 2018, PMID: 29999475, doi: 10.1089/ten.TEC.2017.0513. 

Zhong, Y.; Motavalli, M.; Caplan, A.I.; Welter, J.F.; and Baskaran, H.: Dynamics of intrinsic glucose uptake kinetics in human mesenchymal stem cells during chondrogenesis. Annals of Biomedical Engineering, 46(11):1896-1910, 2018, PMID: 29948374, DOI: 10.1007/s10439-018-2067-x

Wang, K-C.; Egelhoff, T.T.; Caplan, A.I.; Welter, J.F.; Baskaran, H.: ROCK Inhibition promotes development of chondrogenic tissue by improved mass transport, Tissue Engineering Part A, 2018, PMID: 29397789, DOI: 10.1089/ten.TEA.2017.0438 (Epub ahead of print)</p
Verbus, E.A.; Kenyon, J.D.; Sergeeva, O.; Awadallah, A.; Yuan, L.; Welter, J.F.; Caplan, A.I.; Schluchter, M.D.; Khalil, A.M.; and Lee, Z.: Expression of miR-145-5p during chondrogenesis of mesenchymal stem cells 2017 (Submitted to Stem Cells and Translational Medicine)

Mansour, J.M.; Motavalli, M.; Dennis, J.E.; Caplan, A.I.; Berilla, J.A.; and Welter, J.F.: Rapid detection of shear-induced damage in tissue engineered cartilage using ultrasound. (Submitted)

Chou, C.L.; Rivera, A.L.; Williams, V.; Welter, J.F.; Mansour, J.M.; Drazba, J.A.; Sakai, T.; and Baskaran, H.: Micrometer scale guidance of mesenchymal stem cells to form structurally oriented large-scale tissue engineered cartilage. Acta Biomater. 2017 doi: 10.1016/j.actbio.2017.07.016. [Epub ahead of print]

Mishra, R.; Sefcik, R.S.; Bishop, T.J.; Montelone, S.M.; Crouser, N.; Welter, J.F.; Caplan, A.I.; and Dean, D.: Growth factor dose tuning for bone progenitor cell proliferation and differentiation on resorbable poly(propylene fumarate) scaffolds. Tissue Engineering Part C Methods. 2016 22(9):904-913. 

Mansour, J.; Lee, Z.; and Welter, J.: Nondestructive techniques to evaluate the characteristics and development of engineered cartilage. (Invited review). Annals of Biomedical Engineering 2016 44(3):733-49.