Department of Biomedical Engineering
Overview   |  Neural prostheses, neural rehabilitation engineering, and neuromodulation  |   Neural Dynamics and Neurophysiology   |   Neural Regeneration  |   Neural and brain machine interfaces   |  Neural Computation and Control


Stimulating the Future of Medicine

Neural engineering and rehabilitation research applies neuroscience and engineering methods to analyze central and peripheral nervous system function and to design clinical solutions to neurological disorders or injury. Through the application of basic science and engineering techniques, neural engineers develop methods to record from and exert control over the nervous system and associated organ systems. Primary faculty, associated faculty, research associates, and students work in three national centers of education and research in neural engineering and rehabilitation. Our research teams collaborate with four local major medical facilities: MetroHealth Medical Center, University Hospitals Case Medical Center, Cleveland Clinic, and The Louis Stokes Cleveland VA Medical Center. Neural engineering facilities allow researchers to take ideas from basic science through experimental testing and to clinical deployment. Neural engineering research teams are funded by commercial partnerships and grants, including those from the State of Ohio, National Institutes of Health, and other federal sources - in excess of $26 million. Below are a few examples of the ongoing research and applications in neural engineering and rehabilitation.

Neural prostheses, neural rehabilitation engineering, and neuromodulation
Technologies for treating and managing consequences of stroke, spinal cord injury, epilepsy, genito-urinary function, pain, and multiple sclerosis; robot-assisted rehabilitation; deep brain stimulation for treating movement disorders

Neural Dynamics and Neurophysiology
Synchronization and control of neural activity in-vivo and in-vitro, spinal neural circuits, and stochastic resonance in neural networks, analysis and control of epilepsy

Neural Regeneration
Engineer materials and devices to facilitate the growth of neurons for specific applications such as the regeneration of peripheral nerve in case of injury or surgical resection, the regeneration of the spinal cord tissue for spinal cord injury and the regeneration of retinal tissue.

Neural and brain machine interfaces
Bio-inspired materials, cellular-level neural connection, EEG and microelectrodes for cortical control of assistive technologies, interfacing techniques with the peripheral nervous system

Neural Computation and Control
Computational neuroscience; simulation of nerve electrodes, musculo-skeletal systems, and biomechanics; advanced control algorithms

Technology designed to alter or modulate nerve activity by delivering electrical or pharmaceutical agents directly to a target area.
Neuromodulation is applied to nerves either in the peripheral or central nervous system

Bioelectric Medicine
Bioelectronic medicine combines molecular medicine, bioengineering, and neuroscience to discover and develop nerve stimulating and sensing technologies to regulate biological processes and treat disease. It is focused on the autonomic nervous system.

Case Affiliated Laboratories and Centers